B对冷轧IF钢板焊接疲劳性能的影响

对比研究了B对Ti添加和Ti、Nb复合添加的冷轧IF钢板经电阻焊接前后的显微组织和疲劳性能的影响·结果表明,B可以细化这两种IF钢的退火组织和焊接热影响区组织,改善晶界结合强度,提高焊接疲劳强度·疲劳断口分析结果表明,IF钢焊后表现为沿晶断裂特征,B可使IF钢断裂特征得以改善,由沿晶断裂转变成穿晶断裂     

光纤布拉格光栅监测系统在现场监测混凝土挡土墙早期性能中的应用(英文)

应用光纤布拉格光栅温度传感器和应变传感器现场监测了混凝土挡土墙浇注早期的变形和温度变化情况。由于光纤布拉格光栅同时感应温度和变形,需要用布拉格光栅温度传感器对应变传感器进行温度补偿。监测结果表明,光纤布拉格光栅监测系统适用于混凝土早期性能的现场监测,通过与普通传感器监测结果对比,光纤传感器的结果更稳定,准确,且该监测系统可继续对混凝土结构的中长期性能进行实时监测。     

消费者TV家庭冲动购物的激励因素

以TV家庭购物和冲动购买为研究基础，分析冲动购物的激励因素，通过检验设定的问题来确定其影响力。分析有一次以上TV家庭购物的303名消费者的调查资料，得出：（1）分析产品激励因素对专卖商品和流行商品的影响，结果表明，激励冲动购物只对流行商品有影响。（2）在促销激励因素中，提供赠品的激励和扩大信用卡打折期限的激励对冲动购物都有一定影响，后者影响更大。（3）价格激励因素中，大幅度降低商品价值的激励比合理的价值激励对冲动购物影响更大。（4）情境激励因素特性表明，引导销售激励比限量销售激励影响更大。（5）消费者TV家庭购物视听关联特性表明，看TV时间长比与有伴看电视对消费者冲动购物影响更大。     

The Fitzpatrick-Neville-Type Algorithm for Multivariate Vector-Valued Osculatory Rational Interpolation

In this paper,the authors first apply the Fitzpatrick algorithm to multivariate vectorvalued osculatory rational interpolation.Then based on the Fitzpatrick algorithm and the properties of an Hermite interpolation basis,the authors present a Fitzpatrick-Neville-type algorithm for multivariate vector-valued osculatory rational interpolation.It may be used to compute the values of multivariate vector-valued osculatory rational interpolants at some points directly without computing the interpolation function explicitly.     

Variability modeling to develop flexible service-oriented applications

To cope with requirement changes flexibly and rapidly, the existing component-based paradigm is being evolved into a service-oriented computing paradigm. The main characteristic of the service-oriented computing paradigm is that service-oriented applications are developed as loosely coupled services that reflect business concerns. This paradigm also promotes business agility, facilitating quick reactions to business changes. Therefore, to enhance and support the benefits of the service-oriented computing paradigm, we must consider How to improve flexibility and reusability during the development of service-oriented applications. We propose the variability modeling approach to specify and control the common and distinguishing characteristics of service-oriented applications. That is, the key concepts of product-line technology can be used to make service-oriented applications more flexible and reusable. This paper describes variability modeling at two levels; the composition level and the specification level. At the composition level, we describe the variability of composition and the flow of domain services that fulfill business processes. At the specification level, we present a domain service that is an abstract service with variability. The use of our systematic variability modeling approach can greatly increase the flexibility, applicability, and reusability of service-oriented applications.     

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

The efficacy and safety of biological molecules in cancer therapy, such as peptides and small interfering RNAs (siRNAs), could be markedly increased if high concentrations could be achieved and amplified selectively in tumour tissues versus normal tissues after intravenous administration. This has not been achievable so far in humans. We hypothesized that a poxvirus, which evolved for blood-borne systemic spread in mammals, could be engineered for cancer-selective replication and used as a vehicle for the intravenous delivery and expression of transgenes in tumours. JX-594 is an oncolytic poxvirus engineered for replication, transgene expression and amplification in cancer cells harbouring activation of the epidermal growth factor receptor (EGFR)/Ras pathway, followed by cell lysis and anticancer immunity. Here we show in a clinical trial that JX-594 selectively infects, replicates and expresses transgene products in cancer tissue after intravenous infusion, in a dose-related fashion. Normal tissues were not affected clinically. This platform technology opens up the possibility of multifunctional products that selectively express high concentrations of several complementary therapeutic and imaging molecules in metastatic solid tumours in humans.     

小议供应链中的“牛鞭效应”

阐述了牛鞭效应的含义,指出了牛鞭效应的危害,分析了产生牛鞭效应的原因．提出了减缓牛鞭效应的办法。     

Dislocation multi-junctions and strain hardening

At the microscopic scale, the strength of a crystal derives from the motion, multiplication and interaction of distinctive line defects called dislocations. First proposed theoretically in 1934 (refs 1-3) to explain low magnitudes of crystal strength observed experimentally, the existence of dislocations was confirmed two decades later. Much of the research in dislocation physics has since focused on dislocation interactions and their role in strain hardening, a common phenomenon in which continued deformation increases a crystal's strength. The existing theory relates strain hardening to pair-wise dislocation reactions in which two intersecting dislocations form junctions that tie the dislocations together. Here we report that interactions among three dislocations result in the formation of unusual elements of dislocation network topology, termed 'multi-junctions'. We first predict the existence of multi-junctions using dislocation dynamics and atomistic simulations and then confirm their existence by transmission electron microscopy experiments in single-crystal molybdenum. In large-scale dislocation dynamics simulations, multi-junctions present very strong, nearly indestructible, obstacles to dislocation motion and furnish new sources for dislocation multiplication, thereby playing an essential role in the evolution of dislocation microstructure and strength of deforming crystals. Simulation analyses conclude that multi-junctions are responsible for the strong orientation dependence of strain hardening in body-centred cubic crystals.