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71.
72.
基于功能-行为-结构映射的机构系统概念设计模型,通过与功能相关联物理行为的综合,实现功能到结构的转换;通过分析执行动作形式,定义了有效工作时段的动作形式;在确定工作原理的条件下,建立了构造功能与有效工作时段动作映射矩阵的方法.根据专家经验,对能实现一个功能的所有有效工作时段动作进行评价,建立了从整个工艺动作过程的动作方案,集中寻求最优化有效工作时段动作方案的评价规则、数学模型和求解方法,并给出实例. 相似文献
73.
Doerwald L van Genesen ST Onnekink C Marín-Vinader L de Lange F de Jong WW Lubsen NH 《Cellular and molecular life sciences : CMLS》2006,63(6):735-743
The mechanism of the translational thermotolerance provided by the small heat shock proteins (sHsps) αB-crystallin or Hsp27
is unknown. We show here that Hsp27, but not αB-crystallin, increased the pool of mobile stress granule-associated enhanced
green fluorescent protein (EGFP)-eukaryotic translation initiation factor (eIF)4E in heat-shocked cells, as determined by
fluorescence recovery after photobleaching. Hsp27 also partially prevented the sharp decrease in the pool of mobile cytoplasmic
EGFP-eIF4G. sHsps did not prevent the phosphorylation of eIF2α by a heat shock, but promoted dephosphorylation during recovery.
Expression of the C-terminal fragment of GADD34, which causes constitutive dephosphorylation of eIF2α, fully compensated for
the stimulatory effect of αB-crystallin on protein synthesis in heat-shocked cells, but only partially for that of Hsp27.
Our data show that sHsps do not prevent the inhibition of protein synthesis upon heat shock, but restore translation more
rapidly by promoting the dephosphorylation of eIF2α and, in the case of Hsp27, the availability of eIF4E and eIF4G.
Received 9 December 2005; received after revision 16 January 2006; accepted 23 January 2006 相似文献
74.
During the field work of the 1998~1999's and 1999~2000's Chinese National Antarctic Research Expedition (CHNARE) in the Grove Mountains, east Antarctica, some Cenozoic sedimentary debris are found in two terminal moraine banks over the blue ice near Harding Mount in the center of this region. All the debris are of characteristics of glaciogenic diamicton and belong to the products of the glacial movements of the East Antarctic Ice Sheet. In this paper, the authors make a detailed study on the sedimentary environments of the sedimentary debris through petrologic, sedimentological, mineralogical, and geo-chemical methods. Characteristics of their sedimentary textures and structures, grain size distributions, quartz grains' surface textures and features, together with their geo-chemical compositions all show that these sedimentary rocks are a kind of subglacial lodgement tills which are deposited in the ice sheet frontal area by reactions of glacial movements and glaciogenic melt water. Their palaeoenvironmental implications in revealing the retreat history of East Antarctic Ice Sheet are discussed. The authors draw the conclusion from current study that the glacial frontal of the East Antarctica Ice Sheet might have been retreated to this area during the Pliocene Epoch, which represents a warm climate event accompanied by a large-scale ice sheet retreat in Antarctica at that time. 相似文献
75.
A study on knowledge transfer in a mutli-agent organization is performed by applying the basic principle in physics such as the kinetic theory.Based on the theoretical analysis of the knowledge accumulation process and knowledge transfer attributes,a special type of knowledge field(KF)is introduced and the knowledge diffusion equation(KDE)is developed.The evolution of knowledge potential is modeled by lattice kinetic equation and verified by numerical experiments.The new equation-based modeling developed in this paper is meaningful to simulate and predict the knowledge transfer process in firms.The development of the lattice kinetic model(LKM)for knowledge transfer can contribute to the knowledge management theory,and the managers can also simulate the knowledge accumulation process by using the LKM. 相似文献
76.
在无线传感网络中,路由选择是高效使用网络、延长全网络寿命的关键之一.为了提高网络效率和节省网络整体能耗,提出了一种路由选择优化算法,该算法利用没连接到的邻居节点进行数据路由选择,以减少从源节点到目的节点的跳数,进而达到提高网络效率和节省能耗的目的.通过仿真实验对比分析了改进前后的实际效果,实验结果表明改进后的路由选择优化算法减少了ZigBee节点间路由的跳数和延迟,提高了路由效率,节省网络整体能耗. 相似文献
77.
78.
色彩通过其独特的图像、功能和情感成为历史和地区特色的象征。对色彩无意义的使用所导致的视觉压力和低质量生活,阻碍了高质量设计的产生,降低了客户的满意度。虽然色彩有助于以相对较小的成本提高工业竞争力,但没有色彩标准就无法控制其有效性和经济性。为了最大程度地减少色彩的使用数量,色彩应以恰如其分的方式表现出来,并反映基于标准化色彩语言的决策。另外,由于与人类情感息息相关,色彩标准应该是可变并且主观的。因此,色彩标准包含了为改善环境对色彩定量和衡量的全部过程,但在体现各地区环境、个性以及特色方面,色彩标准的掌握尚存在不足之处。 相似文献
79.
Nanofabrication strategies are becoming increasingly expensive and equipment-intensive, and consequently less accessible to researchers. As an alternative, scanning probe lithography has become a popular means of preparing nanoscale structures, in part owing to its relatively low cost and high resolution, and a registration accuracy that exceeds most existing technologies. However, increasing the throughput of cantilever-based scanning probe systems while maintaining their resolution and registration advantages has from the outset been a significant challenge. Even with impressive recent advances in cantilever array design, such arrays tend to be highly specialized for a given application, expensive, and often difficult to implement. It is therefore difficult to imagine commercially viable production methods based on scanning probe systems that rely on conventional cantilevers. Here we describe a low-cost and scalable cantilever-free tip-based nanopatterning method that uses an array of hard silicon tips mounted onto an elastomeric backing. This method-which we term hard-tip, soft-spring lithography-overcomes the throughput problems of cantilever-based scanning probe systems and the resolution limits imposed by the use of elastomeric stamps and tips: it is capable of delivering materials or energy to a surface to create arbitrary patterns of features with sub-50-nm resolution over centimetre-scale areas. We argue that hard-tip, soft-spring lithography is a versatile nanolithography strategy that should be widely adopted by academic and industrial researchers for rapid prototyping applications. 相似文献
80.