Nicotinamide administration alters the activities of hepatic microsomal mixed function oxidases

Summary Systemic action of nicotinamide significantly alters the activities of hepatic drug metabolizing enzymes. Male rats injected with nicotinamide have reduced levels of cytochrome P450, demethylases and aniline hydroxylase. The changes appear to be sex-dependent since in the case of female rats activities of p-nitroanisole-o-demethylase and aniline hydroxylase are enhanced whereas cytochrome P450 content remains unaltered.Authors gratefully acknowledge the encouragement given by Professor A.S. Paintal during the course of this investigation. One of us (J.K.B.) is grateful to the Council of Scientific and Industrial Research, New Delhi, for the award of a research fellowship.     

Calcium sensitivity of succinate and pyruvate dehydrogenases in the denervated amphibian skeletal muscle

Zusammenfassung Es wird nachgewiesen, dass die Aktivität von Succinat Dehydrogenase und von Pyruvat Dehydrogenase in Extrakten normaler und denervierter Muskulatur durch Ca⁺⁺ im pH-Bereich von 5,8 bis 7,8 in verschiedenem Ausmass erhöht bzw. erniedrigt wird.     

Resistance in some wild and cultivated grasses to the phytotoxicity of a systemic fungicide

Zusammenfassung Auf den Blättern einiger Gräser (Aegilops, Triticum, Secale, Hordeum undAvena) wurde der Grad der durch das systemische Fungizid Calixin verursachten Chlorosis näher untersucht.