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121.
Supercoiled DNA folded by non-histone proteins in cultured mammalian cells.   总被引:2,自引:0,他引:2  
T Ide  M Nakane  K Anzai  T Ando 《Nature》1975,258(5534):445-447
  相似文献   
122.
123.
This paper considers a problem of optimal preventive maintenance and replacement schedule of equipment devoted to extracting resources from known deposits. Typical examples are oil drills, mine shovels, etc. At most one replacement of the existing machinery by a new one is allowed. The problem is formulated as an optimal control problem subject to the state constraint that the remaining deposit at any given time is nonnegative. We show that the optimal preventive maintenance, production rates, and the replacement and salvage times of the existing machinery and the new one, if required, can be obtained by solving sequentially a series of free-end-point optimal control problems. Moreover, an algorithm based on this result is developed and used to solve two illustrative examples.  相似文献   
124.
Traditional econometrics has long employed "points" to measure time series data. In real life situations, however, it suffers the loss of volatility information, since many variables are bounded by intervals in a given period. To address this issue, this paper provides a new methodology for interval time series analysis. The concept of "interval stochastic process" is formally defined as a counterpart of "stochastic process" in point-based econometrics. The authors introduce the concepts of interval stationarity, interval statistics (including interval mean, interval variance, etc.) and propose an interval linear model to investigate the dynamic relationships between interval processes. A new interval-based optimization approach for estimation is proposed, and corresponding evaluation criteria are derived. To demonstrate that the new interval method provides valid results, an empirical example on the sterling-dollar exchange rate is presented.  相似文献   
125.
Engineering and research teams often develop new products and technologies by referring to inventions described in patent databases. Efficient patent analysis builds R&D knowledge, reduces new product development time, increases market success, and reduces potential patent infringement. Thus, it is beneficial to automatically and systematically extract information from patent documents in order to improve knowledge sharing and collaboration among R&D team members. In this research, patents are summarized using a combined ontology based and TF-IDF concept clustering approach. The ontology captures the general knowledge and core meaning of patents in a given domain. Then, the proposed methodology extracts, clusters, and integrates the content of a patent to derive a summary and a cluster tree diagram of key terms. Patents from the International Patent Classification (IPC) codes B25C, B25D, B25F (categories for power hand tools) and B24B, C09G and H011 (categories for chemical mechanical polishing) are used as case studies to evaluate the compression ratio, retention ratio, and classification accuracy of the summarization results. The evaluation uses statistics to represent the summary generation and its compression ratio, the ontology based keyword extraction retention ratio, and the summary classification accuracy. The results show that the ontology based approach yields about the same compression ratio as previous non-ontology based research but yields on average an 11% improvement for the retention ratio and a 14% improvement for classification accuracy.  相似文献   
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In this paper we study how organizational learning impacts organizational behavior, and howvendor support quality enhances product adoption and usage behavior.These constructs were verifiedusing Application Software Packages(ASP)-a prewritten, precoded, commercially available set ofprograms that eliminates the need for individuals or organizations to write their own softwareprograms for certain functions. The relationship between ASP usage, usage outcomes and useprocesses were also investigated. Two hundred and ninety-five Chinese, Indian, and Malayentrepreneurships were studied. It was found that usage outcome strongly determines usage, while useprocess has only an indirect relationship (via outcome) on usage. The impact of organizational learningand vendor service quality on usage, usage outcome, and use process were robust. Theoretical andpractical implications of the research are discussed.  相似文献   
128.
This paper proposes an interval method to explore the relationship between the exchange rate of Australian dollar against US dollar and the gold price,using weekly,monthly and quarterly data.With the interval method,interval sample data are formed to present the volatility of variables. The ILS approach is extended to multi-model estimation and the computational schemes are provided. The empirical evidence suggests that the ILS estimates well characterize how the exchange rate relates to the gold price,both in the long-run and short-run.The comparison between the interval and point methods indicates that the difference between the OLS and the ILS estimates is increasing from weekly data to quarterly data,since the lowest frequency point data lost the most information of volatility.  相似文献   
129.
Childbearing outside marriage in western Europe   总被引:1,自引:0,他引:1  
Across most European states in recent decades there have been significant increases in childbearing outside marriage. This article examines the extent to which women have their first child in one of four settings: prior to any partnership; in their first cohabiting partnership; in first marriage; and after a first partnership. Temporal changes in these behaviours and variation according to background characteristics of the women are also examined. For the women who had a child outside any partnership, we examine the extent to which they go on to form partnerships and how long after the birth this happens. For those who had their first child within a cohabiting union, we examine the extent to which they marry and how long after the birth this occurs. Finally, we investigate whether children born within cohabiting unions that do and do not convert into marriages are more or less likely than those born within marriage to see their parents separate.  相似文献   
130.
Patent documents are unique external sources of information that reveal the core technology underlying new inventions.Patents also serve as a strategic data source that can be mined to discover state-of-the-art technical development and subsequently help guide R&D investments.This research incorporates an ontology schema to extract and represent patent concepts.A clustering algorithm with non-exhaustive overlaps is proposed to overcome deficiencies with exhaustive clustering methods used in patent mining and technology discovery.The non-exhaustive clustering approach allows for the clustering of patent documents with overlapping technical findings and claims,a feature that enables the grouping of patents that define related key innovations.Legal advisors can use this approach to study potential cases of patent infringement or devise strategies to avoid litigation.The case study demonstrates the use of non-exhaustive overlaps algorithm by clustering US and Japan radio frequency identification (RFID) patents and by analyzing the legal implications of automated discovery of patent infringement.  相似文献   
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