Effect of prostaglandin F2α on the secretion of pancreatic juice induced by secretin and by dopamine

Zusammenfassung Die Wirksamkeit von Prostaglandin F₂ (PGF₂) auf die exokrine Pankreassekretion wurde an einem mit Blut perfundiereten Pankreas-Präparat des Hundes untersucht. PGF₂ (100 g) hemmte die durch Sekretin stimuliete, aber nicht die durch Dopamin stimulierte Sekretion.     

A new intracellular medium for prolonged viability of noradrenergic storage vesicles from rat brain

Summary The biochemical lifetime of noradrenergic storage vesicles from rat brain is greatly extended in a medium based upon the membrane impermeable anion D-tartrate. Examination of the MgATP-dependent accumulation of (–)-³H-norepinephrine suggests that this medium may more closely approximate the intracellular environment of the storage vesicle, and may better support electrochemical gradients existing across the vesicle membrane.Acknowledgments. This work was supported by grant NS 15374 (NIH) of the United States Public Heath Service.