全文获取类型
收费全文 | 1201篇 |
免费 | 25篇 |
国内免费 | 135篇 |
专业分类
系统科学 | 49篇 |
丛书文集 | 18篇 |
教育与普及 | 27篇 |
理论与方法论 | 7篇 |
现状及发展 | 7篇 |
研究方法 | 5篇 |
综合类 | 1248篇 |
出版年
2024年 | 4篇 |
2023年 | 14篇 |
2022年 | 14篇 |
2021年 | 17篇 |
2020年 | 13篇 |
2019年 | 9篇 |
2018年 | 10篇 |
2017年 | 14篇 |
2016年 | 14篇 |
2015年 | 39篇 |
2014年 | 47篇 |
2013年 | 62篇 |
2012年 | 64篇 |
2011年 | 66篇 |
2010年 | 51篇 |
2009年 | 59篇 |
2008年 | 76篇 |
2007年 | 75篇 |
2006年 | 66篇 |
2005年 | 56篇 |
2004年 | 43篇 |
2003年 | 58篇 |
2002年 | 67篇 |
2001年 | 56篇 |
2000年 | 35篇 |
1999年 | 50篇 |
1998年 | 48篇 |
1997年 | 27篇 |
1996年 | 30篇 |
1995年 | 29篇 |
1994年 | 38篇 |
1993年 | 21篇 |
1992年 | 11篇 |
1991年 | 22篇 |
1990年 | 12篇 |
1989年 | 22篇 |
1988年 | 9篇 |
1987年 | 4篇 |
1986年 | 6篇 |
1985年 | 1篇 |
1984年 | 2篇 |
排序方式: 共有1361条查询结果,搜索用时 15 毫秒
91.
本文研究了虎纹蛙产卵前后血浆性激素变化,得到如下结果;雄性虎纹蛙在交配期血浆睾酮的含量较非交配期高,提示间质细胞分泌的激素与精子的形成相关。雌性虎纹蛙在产卵前血浆雌二醇含量较产卵后高,说明卵泡分泌的激素可能影响其他性征的发育。 相似文献
92.
93.
An efficient culture medium producing a bacterial elastase with high yields was developed further following preliminary studies by means of response surface method. Central composite design (CCD) and response surface methodology were applied to optimize the medium constituents. A central composite design was used to explain the combined effect of three medium constituents, viz, glucose, K(2)HPO(4), MgSO(4).7H(2)O. The strain produced more elastase in the completely optimized medium, as compared with the partially optimized medium. The fitted model of the second model, as per RSM, showed that glucose was 7.4 g/100 ml, casein 1.13 g/100 ml, corn steep flour 0.616 g/100 ml, K(2)HPO(4) 0.206 g/100 ml and MgSO(4).7H(2)O 0.034 g/100 ml. The fermentation kinetics of these two culture media in the flask experiments were analyzed. It was found that the highest elastase productivity occurred at 54 hours. Higher glucose concentration had inhibitory effect on elastase production. At the same time, we observed that the glucose consumption rate was slow in the completely optimized medium, which can explain the lag period of the highest elastase production. Some metal ions and surfactant additives also affected elastase production and cell growth. 相似文献
94.
Reverse engineering in the manufacturing field is a process in which the digitized data are obtained from an existing object model or a part of it, and then the CAD model is reconstructed. This paper presents an RBF neural network approach to modify and fit the digitized data. The centers for the RBF are selected by using the orthogonal least squares learning algorithm. A mathematically known surface is used for generating a number of samples for training the networks. The trained networks then generated a number of new points which were compared with the calculating points from the equations. Moreover, a series of practice digitizing curves are used to test the approach. The results showed that this approach is effective in modifying and fitting digitized data and generating data points to reconstruct the surface model. 相似文献
95.
Glycine binding primes NMDA receptor internalization 总被引:18,自引:0,他引:18
NMDA (N-methyl-d-aspartate) receptors (NMDARs) are a principal subtype of excitatory ligand-gated ion channel with prominent roles in physiological and disease processes in the central nervous system. Recognition that glycine potentiates NMDAR-mediated currents as well as being a requisite co-agonist of the NMDAR subtype of 'glutamate' receptor profoundly changed our understanding of chemical synaptic communication in the central nervous system. The binding of both glycine and glutamate is necessary to cause opening of the NMDAR conductance pore. Although binding of either agonist alone is insufficient to cause current flow through the channel, we report here that stimulation of the glycine site initiates signalling through the NMDAR complex, priming the receptors for clathrin-dependent endocytosis. Glycine binding alone does not cause the receptor to be endocytosed; this requires both glycine and glutamate site activation of NMDARs. The priming effect of glycine is mimicked by the NMDAR glycine site agonist d-serine, and is blocked by competitive glycine site antagonists. Synaptic as well as extrasynaptic NMDARs are primed for internalization by glycine site stimulation. Our results demonstrate transmembrane signal transduction through activating the glycine site of NMDARs, and elucidate a model for modulating cell-cell communication in the central nervous system. 相似文献
96.
Grove Mountains (GRV)99027: A new Martian meteorite 总被引:10,自引:0,他引:10
LINYangting WANGDaode MIAOBingkui OUYANGZiyuan LIUXiaohan JUYitai 《科学通报(英文版)》2003,48(16):1771-1774
We report the petrography, mineral chemistry and oxygen isotopic composition of GRV 99027, a new Martian meteorite recently collected during the 16th Chinese Antarctic Research Expedition. This meteorite consists of two textural regions. The interstitial region is characterized by the presence of plagioclase and phosphate, and higher FeO contents of olivine and orthopyroxene, in comparison with the poikilitic region. All of the observations are similar to the three known Martian lherzolites. We classify GRV 99027 as the fourth sample of Martian lherzolite. 相似文献
97.
全面介绍新时期应用型人才培养模式中实践教学体系的构建与发展,并对实践教学体系构建中的指导思想、课程实验、课程设计、实习实训、毕业论文、技能训练与电子竞赛等方面进行了详细阐述. 相似文献
98.
新时期植物学野外实习的困惑与对策 总被引:2,自引:0,他引:2
野外实习是植物学教学的重要实践环节,实习的方法、手段和内容已经形成了固定模式,但随着形势的发展,新的问题被提出,如国家、地方对实习地的法律保护,实习经费的不足,山林的承包和封山育林政策,学生的吃苦耐劳及团队精神欠缺等,都对实习工作形成了制约。为适应新形势,保证实习工作的质量,提出了充分利用当地野生植物资源,适当减少集中实习的学时,多途径筹措实习经费,加强植物保护方面的法律知识学习,增强学生自然保护和尊重他人劳动的意识,严明纪律、严格管理等举措,并建议修订已有的野外实习工作规范。 相似文献
99.
100.