Effekt des 6-hydroxydopamin auf Hauthomotransplantation der Mäuse

Summary As is known, 6-HD destroys the sympathetic trunc when given to new-born mice. In these mice (weighing 18 g) skin homo-transplantations were made and it was found that the homografts strikingly survived.     

Untersuchung antileukämischer Substanzen an der Hühnerleukose

Summary In leukosis of chickens caused by administration of 1-m-Tolylsemicarbazide (Maretin-Bayer) Butzolidin caused a reduction of the number of leucocytes to normal values. This action might be attributed to a cytostatic effect of Butazolidin.     

Detection of regulatory variation in mouse genes

Functional polymorphism in genes can be classified as coding variation, altering the amino-acid sequence of the encoded protein, or regulatory variation, affecting the level or pattern of expression of the gene. Coding variation can be recognized directly from DNA sequence, and consequently its frequency and characteristics have been extensively described. By contrast, virtually nothing is known about the extent to which gene regulation varies in populations. Yet it is likely that regulatory variants are important in modulating gene function: alterations in gene regulation have been proposed to influence disease susceptibility and to have been the primary substrate for the evolution of species. Here, we report a systematic study to assess the extent of cis-acting regulatory variation in 69 genes across four inbred mouse strains. We find that at least four of these genes show allelic differences in expression level of 1.5-fold or greater, and that some of these differences are tissue specific. The results show that the impact of regulatory variants can be detected at a significant frequency in a genomic survey and suggest that such variation may have important consequences for organismal phenotype and evolution. The results indicate that larger-scale surveys in both mouse and human could identify a substantial number of genes with common regulatory variation.     

自我治疗:动物的生存特技

<正>鸟类、蜜蜂、蜥蜴、大象与黑猩猩等都拥有这样的生存技能——自我治疗。它们总会吃些植物来杀灭体内的寄生虫、细菌或病毒,以此缓解症状、预防疾病,或者纯粹是为了帮助消化。有些大脑只有图钉帽一样大的物种,都会不可思议地在需要的时候专门找来特定的植物吃下去,或用其他特殊方式对其加以利用。遛狗时你有看到过狗吃草吗?不用感到惊讶,那是一种自我治疗。狗如果吃草,那说明它可能肚     

Champsodontidae (Pisces: Trachinoidei) in the Eastern Mediterranean: how many species are there?

ABSTRACT

Three marine fish species of the Indo-Pacific genus Champsodon were reported as invasive species in the Eastern Mediterranean between 2009 and 2012; Champsodon nudivittis, C. vorax, and C. capensis. These are presumed to invade through the Suez Canal, but only C. nudivittis is known from the Red Sea, so the presence of C. vorax and C. capensis is surprising. To test the validity of the taxonomic identification of these two species, this study combined traditional morphology, genetic barcoding, and photography investigation. Our results demonstrate that only one species, C. nudivittis, has migrated into the Eastern Mediterranean.