The Huntington's disease candidate region exhibits many different haplotypes.

Analysis of 78 Huntington's disease (HD) chromosomes with multi-allele markers revealed 26 different haplotypes, suggesting a variety of independent HD mutations. The most frequent haplotype, accounting for about one third of disease chromosomes, suggests that the disease gene is between D4S182 and D4S180. However, the paucity of an expected class of chromosomes that can be related to this major haplotype by assuming single crossovers may reflect the operation of other mechanisms in creating haplotype diversity. Some of these mechanisms sustain alternative scenarios that do not require a multiple mutational origin for HD and/or its positioning between D4S182 and D4S180.     

双核铕－邻甲基苯甲酸－邻菲罗啉三元配合物的晶体结构

双核铕－邻甲基苯甲酸－邻菲罗啉三元配合物的晶体结构王瑞芬，王明昭，金林培，蔡冠梁（北京师范大学化学系，１００８７５，北京；解放军防化指挥工程学院，１０２２０５，北京；第一作者，４４岁，女，副教授）关键词铕；三元配合物；晶体结构分类号Ｏ７４１．６；Ｏ６...