Control of cell growth: Rag GTPases in activation of TORC1

The target of rapamycin (TOR) is a central regulator controlling cell growth. TOR is highly conserved from yeast to mammals, and is deregulated in human cancers and diabetes. TOR complex 1 (TORC1) integrates signals from growth factors, cellular energy status, stress, and amino acids to control cell growth, mitochondrial metabolism, and lipid biosynthesis. The mechanisms of growth factors and cellular energy status in regulating TORC1 have been well established, whereas the mechanism by which amino acid induces TORC1 remains largely unknown. Recent studies revealed that Rag GTPases play a central role in the regulation of TORC1 activation in response to amino acids. In this review, we will discuss the recent progress in our understanding of Rag GTPase-regulated TORC1 activation in response to amino acids. Particular focus will be given to the function of Rag GTPases in TORC1 activation and how Rag GTPases are regulated by amino acids.     

哈尔滨市城市水资源与可持续利用

本文在分析市区水资源的基础上,着探讨了水资源开发利用存在的问题及解决途径。     

关于共轭空间X~*中有界闭凸集的端点

本文首先给出一个反例,说明共轭空间X中有界闭凸集可以无端点,从而指出了《最优控制系统的微分方程理论》一文引理3的错误,并指出此引理结论成立的条件。     

Image Retrieval Based on Objects＇ Spatial Orientation Relationships

A new concept of characteristic scanning radial (CSR) is proposed for the segmented image on the basis of two shape-speciiic points oi its shape-objects. Subsequently, two characteristic attribute sequences (CAS) of relative distance and relative direction are derived to represent the spatial orientation relationships among objects of the image. A novel image retrieval algorithm is presented using these two CASs. The proposed retrieval approach not only satisfies the transformational invariance, but also attains the quantitative comparison of matching. Experiments identify the effectiveness and efficiency of the algorithm adequately.     

高师化学系毕业生质量评价指标体系建立的基本原则和评价模式

本文探讨了高师化学系毕业生质量评价的基本原则,提出了采用T值分级法的综合评价模式,并例证了这种模式优于现行的一般测评方法。     

论我国民事主体的多元结构

民法作为法律体系中的重要法律部门,对规范市场经济的运作具有极其重要的作用。随着改革开放的不断深入,特别是对82年宪法的修正,把社会主义市场经济成份中私有制经济和个体经济提高至与公有制经济平等的法律地位,这一深刻的变革将促使不同经济成份之间以及同一经济成份不同经营者之间的横向经济联系,从而使得我国传统民事主体范围已被突破,而必然呈现多元化。     

多样本球性检验的似然比统计量的渐近分布

设Λ是检验多样本球性的修改似然比准则,本文给出了在某些接近于原假设的各择假设下Λ的非零分布的渐近展开式.     

井下架线电机车防追尾机

本文介绍了井下架线电机车防追尾原理及行车信号发讯机与行车信号收讯机的电路原理。     

钛基氧化物涂层金属阳极放氧放氯活化能的测定

本文测量了钛基锡锑钴电极、贵金属(钯、铂、铱)掺杂的锡锑钴电极,以及钌钛系列氧化物涂层电极的放氯放氧活化能的数据。从活化能的角度比较了一定电势下各类电极的催化活性。得出了锡锑钴系列电极在某些电化学性能方面优于钌钛系列阳极的结论。为开发、使用锡锑钴系列阳极提供了一定的动力学参数。     

共沉淀法制备Fe3O4超微粒过程中Fe^2＋离子氧化的影响

利用化学共沉淀方法制备Fe3O4超微粒样品，用透射电子显微镜（TEM）及X－ray衍射仪分别对样品的形貌，粒度及成份进行测试和分析，讨论了制备样品过程中Fe^2 离子的氧化对样品的影响。