Differential effects of prostaglandins and isoproterenol on cAMP content and Na,K pump activity in rat submandibular acini

Summary The -adrenergic agonist isoproterenol and prostaglandins E₁ and E₂ (but not F₂) increased the cAMP content of rat submandibular acini in vitro, but only isoproterenol enhanced ouabain-sensitive⁸⁶Rb (K) uptake. These findings suggest that cAMP is not involved in the activation of the Na, K pump in salivary cells.     

用爆炸波起爆癸烷云雾的两种模式

用垂直激波管研究了400μm癸烷液滴与空气混合物的爆炸波起爆。每种混合物有两个极限起爆能值,即高值Ecu,和低值Ecl。当起爆能的值高于Ecu时,观察到100%发生爆轰;而当其低于Ecl时,就不会发生爆轰。有趣的是,当起爆能水平在Ecu和Ecl之间时观察到对应于不同的起爆能水平有不同的起爆行为。如实验结果所表明的,爆轰的激发不仅是由于直接起爆,而且也由于“爆燃”到爆轰的转变。     

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid

Cellulose is the most abundant renewable carbon resource on earth and is an indispensable raw material for the wood, paper, and textile industries. A model system to study the mechanism of cellulose biogenesis is the bacterium Acetobacter xylinum which produces pure cellulose as an extracellular product. It was from this organism that in vitro preparations which possessed high levels of cellulose synthase activity were first obtained in both membranous and soluble forms. We recently demonstrated that this activity is subject to a complex multi-component regulatory system, in which the synthase is directly affected by an unusual cyclic nucleotide activator enzymatically formed from GTP, and indirectly by a Ca (2+) -sensitive phosphodiesterase which degrades the activator. The cellulose synthase activator (CSA) has now been identified as bis-(3' 5')-cyclic diguanylic acid (5'G3'p5'G3'p) on the basis of mass spectroscopic data, nuclear magnetic resonance analysis and comparison with chemically synthesized material. We also report here on intermediary steps in the synthesis and degradation of this novel circular dinucleotide, which have been integrated into a model for the regulation of cellulose synthesis.     

液压蓄能式风力机组并网转速解耦优化控制

针对在风速、同步发电机负载变化情况下,液压蓄能式风力机组并网转速控制问题,提出一种新型并网转速控制方法——解耦广义预测优化控制方法（Decoupled Generalized Predictive Optimization Control, DGPOC）.首先,DGPOC利用基于广义预测的前馈解耦方法解除变量马达摆角和蓄能器比例阀开度之间的耦合关系,进而调节蓄能器比例阀,依靠蓄能器吸收波动流量,同步调节变量马达摆角实现恒转速控制,解决因风速、同步发电机负载变化引起的变量马达转速波动问题; 其次,将蓄能器比例阀的能量损耗作为性能约束项,加入到优化目标函数中,求取最优控制量,从而提高液压蓄能式风力机组风能利用率; 最后,利用建立的MATLAB-AMESim联合仿真实验平台验证DGPOC方法的有效性.实验结果表明： DGPOC方法不仅可以实现变量马达摆角和蓄能器比例阀开度两个变量的解耦,提升变量马达转速控制的快速性及鲁棒性,而且能够降低系统的能量损耗.