The effect of D-6-methyl-8-[β-isopropylaminoethyl] ergoline-I on the lactation in nursing rats

D-6-Methyl-8-[-isopropylaminoethyl] ergoline-I [VÚFB-10726], beginning from the dose of 0.05 mg/kg p.o., suppresses lactation through the inhibition of prolactin secretion in nursing rats.     

Sur l'inversion de l'action hypertensive de la prostaglandine F2α, chez le rat

Summary In normal rats, prostaglandin F₂ is a potent vasoconstrictor. The corresponding systemic hypertension is progressively attenuated by tachyphylaxis, revealing a longlasting fall of blood pressure. Tachyphylaxis is accelerated by previous injection of arachidonic acid and bradykinin. The vasodepressive activity of PGF₂ is inhibited by indomethacin.

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Nous remercions vivement le docteurPike (Upjohn, Kalamazoo) qui nous a fourni gracieusement ces prostaglandines.     

Influence of cyclic nucleotides on protein synthesis in vascular smooth muscle

Summary The incorporation of leucice-¹⁴C into protein in bovine mesenteric arteries was augmented by cyclic GMP (10^–3 M) and decreased by cyclic AMP (10^–3 M). There was no effect of 5 AMP (10^–3 M). The phosphodiesterase inhibiting drugs theophylline (10^–3 M) and papaverine (5×10^–5 g/ml) both decreased the leucine-¹⁴C incorporation.We are indebted to Mrs.Lena Burlin for hear assistance. Finacial support has been provided by the Swedish State Medical Research Council (No. 04X-101X-4498).     

Ecdysone 20-hydroxylase from the midgut of the tobacco hornworm (Manduca sexta L.)

Summary An ecdysone 20-hydroxylase enzyme system that converts -ecdysone to 20-hydroxyecdysone was prepared from the midgut of the tobacco hornworm prepupa. This partially purified enzyme is NADPH dependent and is localized in the mitochondrial fraction of the midgut tissue.     

Effect of 723-1723-1723-1on ethanol withdrawal in mice

Summary ⁹ (10 mg/kg, i.p.) administered to mice immediately after withdrawal from a 3-day exposure to ethanol vapor was found to intensify withdrawal reactions. No effect was seen when ⁹ was administered chronically during the exposure to ethanol.     

RNA synthesis in α-amanitin-poisoned rats: Prevention of recovery by inhibition of protein synthesis

Summary The treatment with cycloheximide of rats previously poisoned with -amanitin hinders the recovery of RNA synthesis observed in the liver of rats treated with -amanitin alone. The recovery of RNA synthesis can be ascribed to the capability of poisoned rats to synthesize new RNA-polymerase II.Acknowledgments: We thank ProfessorT. Wieland for the generous gift of -amanitin. This work was supported by grants from C.N.R., Rome, and by Pallotti's legacy for Cancer Research.     

泰国中-新生代热带植物木化石研究

泰国东北部柯叻府及邻区中-新生代木化石非常丰富并保存有完好的解剖构造,是探究热带植被历史、古气候演化以及古环境变迁等问题的重要实证材料.最近的野外调查和专题研究确认该地区中-新生代木化石11科19属约50个种或种级分类单元,分别隶属于裸子植物和被子植物两大分类群,其中有5科7属20种(包括未定种)为前人在泰国未曾报道的类型.当前木材化石群揭示出在中生代后期,泰国东北部热带针叶树植被以南洋杉科为主;在中新世-更新世时期,该地区主要发育落叶和常绿阔叶树植被,代表热带气候环境.     

Fe/Cr(001)超晶格层间耦合和自旋极化的第一性原理计算

采用基于密度泛函理论的平面波赝势法对Fe／Cr（001）起晶格的层间耦合和自旋极化进行了系统地研究．结果表明：理想Fe／Cr超晶格的层间耦合随反铁磁Cr层层数的增加呈短周期性振荡；在较稳定的结构中，整个Cr层都以较大的磁矩被极化，且极化程度受铁磁层原子数的影响较大．     

A carbon- and oxygen-isotope record of recent environ- mental change from Qinghai Lake, NE Tibetan Plateau

An understanding of natural climatic variability is essential for evaluating anthropogenic impacts on recent and future climate[1—3]. Due to the lack of lengthy instrumental records, such an understanding must be gained from natural archives of climate change. Palaeolimnological indicators of past lake levels may provide a sensitive record of changes in effective precipitation in closed basins. This approach is particularly relevant on the Tibetan Plateau, where instrumental records are very…