Lymphatic metastasis of tumour; persistent transport of cells

Summary A model of lymphatic metastasis established by injecting Walker rat carcinoma cells into the rat footpad was used to study the output of tumour cells from the footpad. The lymphatic efferent from the footpad was cannulated in a group of rats with advanced neoplasm; it was shown that the output of tumou cells was continuou over periods up to 90 min and ranged from 10²–10⁵ cells/min.Acknowledgment. This work was supported by a grant from the National Cancer Institute of Canada to C.R.F. and I.C. We are grateful to Mrs W. Kao and Mr I. Etches for meticulous technical help and to the Photographic Section, Department of Pathology for illustrations. Dr V.S. Gupta of Veterinary Physiology, University of Saskatchewan supplied the tumour for transplantation.     

Mitogenic effect of sodium phenobarbital and rat liver arginase activity

Résumé Au cours de la régénération du foie normal des rats, on a constaté une augmentation — statistiquement significative — de l'activité arginasique dans la phase prémitotique. Chez des animaux traités par le phénobarbital, l'activité arginasique augmente encore davantage dans la phase prémitotique du foie régénéré.     

ATPase activity of two rabbit laryngeal muscles

Zusammenfassung Die Myofibrillen- und Myosin-ATPase-Aktivität des schnellen «roten» M. thyroarytenoideus von Kaninchen ist höher als die ATPase-Aktivität des «weissen» M. extensor digitorum longus und wesentlich höher als die ATPase-Aktivität des «roten» M. soleus. Daraus folgt, dass in Abhängigkeit besonderer funktioneller Ansprüche auch rote Muskeln schnell sein können.