好稿外流外稿选优

“好稿外流”造成学报稿原匮乏的情况，在市属高校不同程度地存在着；与此同时，“外稿”却与日俱增，补充了学报的文稿，也带来了用稿的矛盾。解决这个矛盾的正确办法是既不反对好稿外流，又要做了外稿选优的工作，以保证学报的稿源和质量     

钻井环空固液两相流压降模型理论分析

针对直井钻进过程中环空内岩屑运移的特点，对环空中固液两相流动压降进行了理论分析。采用因次分析的方法综合考虑了影响压降的诸多因素，导出了固相摩阻系数与傅劳德数之间的关系，提出了总摩阻系数的理论计算公式，修正了过去计算环空压降时忽略固相引起的压降，为准确进行水力优化设计提供了参考依据。     

葡萄糖氧化酶发酵动力学的研究

利用恒化器研究了葡萄糖氧化酶（ＧＯＤ）发酵动力学，建立了较为合理的恒化培养系统。对采集的数据用计算机进行回归，求得最大比生长速率μｍａｘ＝０．２２５ｈ－１、饱和常数Ｋｓ＝８．９１ｇ／Ｌ、基质得率系数ＹＧｍａｘ＝０．４９ｇ／ｇ以及维持系数ｍ＝０．０２ｇ／ｇ·ｈ。并研究了ｐＨ、ＤＯ、ＮＨ２－Ｎ、葡萄糖酸、细胞产率，酶比活及体积产酶速率等参数随比生长速率变化的规律。在Ｄ＝０．１３１ｈ－１下体积产酶速率（ＤＥ）达最大值，为３．４６×１６．６７μｍｏｌ／ｓ·Ｌ·ｈ，是分批发酵最大体积产酶速率（１．５３×１６．６７μｍｏｌ／ｓ·Ｌ·ｈ）的２．２６倍。     

Determination on ^87Sr/^86Sr ratio and stratigraphic dating of single-grain foraminifera

Information on palaeoocean and palaeoclimate can be recorded in foraminifera, and formation ages of the fo- raminifera are nevertheless essential for such study of pa- laeoenvironment. The growth rate of seamount ferroman- ganese crusts is normally very l…     

《汽车服务工程》 本科专业课程结构研究与设置

本文旨在分析《汽车服务工程》培养目标、素质标准、能力要求的基础上,对该专业的课程结构及其特点进行了研究。以基础素质教育、工程技术教育和人文社科教育三大类课程构成《汽车服务工程》专业课程体系,明确工科基础特点,扩大专业知识范围,工程技术与人文社科融合为基点设置课程,以实现“厚基础,宽专业”的高素质应用型人才培养模式的基本要求。     

利用体系结构的建模方法支持测试设计的重用

将体系结构的建模方法应用于测试设计,测试设计和软件设计自上至下同步进行.利用基于体系结构的建模方法将软件设计规范和测试设计规范紧密结合,形成统一的模型描述框架,从而构建层次化的测试设计模型,同时给出了测试用例之间关系的精确定义.结论是:基于体系结构的建模方法能够大大提高软件开发过程中各工作产品的可测试性和测试用例的可维护性,能够有效地支持测试设计的重用.     

Effect of New O-Superfamily Conotoxin on Voltage-Activated Currents of Hippocampal Neurons

The effects of a new O-superfamily conotoxin, SO3, on sodium current (INa), transient A-type potassium currents (IA), and delayed rectified potassium currents (IK), were examined in cultured rat hippocampal neurons using the whole-cell patch clamp technique. Addition of SO3 caused a concentration-dependent, rapidly developing, and reversible inhibition of voltage-activated currents. The IC50 values for the blockage of INa, IA, and IK were calculated as 0.49, 33.9, and 7.6 μmol/L, respectively. The determined Hill coefficients were 1.7, 0.6, and 1.2, respectively. These results indicate that SO3 can selectively inhibit neuronal sodium and potassium currents.     

我国农业在物联网模式下发展探索

近十年,国外发达国家的物联网技术已经在农业方面得到广泛应用。而我国农业物联网技术还属于起步阶段,那么如何借鉴发达国家的农业物联网发展模式经验,构建适合我国农业物联网应用平台,建立农业物联网产品标准化体系,研发完善农业物联网核心技术产品,用多元化的技术成果指导传统农业向现代化农业转变,将是我国农业物联网发展的关键点。     

Developing anti-neoplastic biotherapeutics against eIF4F

Biotherapeutics have revolutionized modern medicine by providing medicines that would not have been possible with small molecules. With respect to cancer therapies, this represents the current sector of the pharmaceutical industry having the largest therapeutic impact, as exemplified by the development of recombinant antibodies and cell-based therapies. In cancer, one of the most common regulatory alterations is the perturbation of translational control. Among these, changes in eukaryotic initiation factor 4F (eIF4F) are associated with tumor initiation, progression, and drug resistance in a number of settings. This, coupled with the fact that systemic suppression of eIF4F appears well tolerated, indicates that therapeutic agents targeting eIF4F hold much therapeutic potential. Here, we discuss opportunities offered by biologicals for this purpose.     

Optimal policy with a total order quantity commitment contract in the presence of a spot market

In this paper,the optimal policy is considered when the buyer faces two supply sources:one is the contract supplier from which the buyer orders over a specific contract period(say,a year) at a pre-agreed price,and the other is the spot market.However,when ordering from the contract supplier,the buyer must fulfill a pre-determined total order quantity,or the so-called definite total order quantity commitment,over the whole contract period.In other words,the commitment secures the buyer a fixed price but obliges him/her a total order quantity over the contract period.Although the spot market gives the buyer more flexibility in terms of order quantities,its prices are volatile.Such a combination of contract and spot procurements is often observed in practice.Within the contract period,there are multiple sub-periods,during each of which the buyer reviews the inventory,issues an individual order,and uses the on-hand inventory to meet the random demand.Thus,in each(ordering) period,the buyer will weigh between the current known spot price(by procuring from the spot market) and a lower future price(by waiting while consuming the remaining commitment).An optimal dual ordering policy is characterized for each period,depending on the on-hand inventory level,the spot price,and the remaining commitment quantity.The optimal policy in each period is also shown to be independent of the contract price.Through a numerical study,the inventory cost is demonstrated to be(1) insensitive to the contract price when the total commitment quantity is lower than the total expected demand over the contract period and(2) non-increasing in the variability of spot prices.