某高校大学生复发性口腔溃疡诱发因素调查研究

目的:调查研究某高校大学生复发性口腔溃疡的诱发因素,为大学生预防复发性口腔溃疡提出建议.方法:采用自编问卷进行调查,多阶段分层随机抽样抽取样本;发放问卷1 045份,回收有效问卷987份;使用EpiData软件建立数据库,使用SPSS16.0进行数据处理和统计分析,研究复发性口腔溃疡与各因素的关系.结果:研究发现抽烟(P=0.003)、免疫力下降因素(P=0.000)、心理因素(P=0.022)、饮食类型(P=0.000)、内分泌(P=0.000)、食用烧烤(P=0.000)、消化系统慢性疾病(P=0.000)和口腔卫生(P=0.013)与复发性口腔溃疡的发生有统计学意义.结论:抽烟、免疫力下降因素、心理因素、饮食类型、内分泌、食用烧烤、消化系统慢性疾病和口腔卫生等是复发性口腔溃疡的诱发因素.     

高校廉政文化建设的理论与实践

高校廉政文化是社会主义廉政文化的重要组成部分,反映了当代中国先进文化的价值取向.加强高校廉政文化建设是践行"三个代表"重要思想的具体体现,是净化高校发展环境的迫切需要,同时也是培养高素质人才的内在要求.当前,高校加强廉政文化建设,主要应立足于建设廉政精神文化、廉政制度文化和廉政物质文化.     

一种基于密度的数据流检测算法SWKLOF

总结目前数据流在线检测算法的优缺点,提出了一种新的数据流在线检测算法—SWKLOF。该算法采用滑动时间窗口对数据流进行封装,用k-距离进行剪枝,剔除大部分正常数据,对剩余疑似异常数据采用局部离群因子LOF(local outlier factor)进一步精确筛选。理论分析和实验结果表明该算法降低了时间复杂度,提高了检测准确性。     

牛蒡子炮制前后质量标志物的网络药理学研究

研究牛蒡子炮制前后质量标志物的药效作用靶点,构建“成分-靶点-疾病”作用网络,解释牛蒡子炮制机理。 通过PharmMapper数据库筛选牛蒡子炮制前后6个质量标志物成分的潜在作用靶点,通过STRING数据库构建靶点蛋白相互作用网络;采用Cytoscape软件构建“成分-靶点-疾病”网络图。牛蒡子炮制前后质量标志物成分可通过多靶点作用,在抗肿瘤、抗炎、心脏损伤保护、抗高血压等方面发挥作用,且各个成分的相关作用靶点相互交联,共同发挥多靶点药效作用。通过网络药理学方法揭示了牛蒡子炮制前后质量标志物的主要药效作用,为进一步深入揭示其炮制机理提供了科学依据。     

城市老旧小区老年人户外活动休息点分布量化研究

为解决城市老旧小区内老年人户外活动休息点建设中易受主观因素影响,且未能真实反映老年人群体需求,无法快速评估和预测休息点的分布问题,通过跟踪记录与问卷访谈的方法,研究了南京市鼓楼区9个老旧小区老年人户外步行活动的特征,提出最优步行距离的概念及其计算方法用于描述特定老年人群体户外活动的水平,对老年人群体的户外活动步行距离进行量化,并以此为基础建立社区老年人户外活动休息点的分布模型,对9个小区休息点的理想分布进行计算,结果表明,该模型有利于客观地评价城市老旧小区中老年人户外活动休息空间的建设状况,有利于快速发现建成小区中休息点分布的不足,有利于直观预测规划设计中的老年人户外休息空间配置水平。     

The new sideway of CNTF signal transduction pathway

The action of ciliary neurotrophic factor (CNTF) on intercellular free Ca²⁺ concentrations [Ca²⁺]_i induced by glutamate (Glu) in primary cultured hippocampal neurons were detected with Fura2/AM, a Ca²⁺-sensitive fluorophore, and the morphological influence of G-protein on it was objected. Glu could induce rapid increase of [Ca²⁺]_i in hippocampal neurons. CNTF had no significant action on [Ca²⁺]_i in resting hippocampal neurons. However, after incubation of CNTF for 5 min, the increase of [Ca²⁺]_i in hippocampal neurons rapidly induced by Glu was inhibited. Pretussis toxin (PTX)-sensitive G protein could block the action. These results indicate that a new non-genomic rapid sideway might exist in the upper stream of CNTF signal transduction pathway, which was related to Ca²⁺ signal transduction. Keywords:     

Geochronology of the Hannan intrusive complex to adjoin the Qinling orogen and its rapid cooling reason

The geochronological works for the Hannan intrusive complex, cosisting of the gabbro-quartz dio-rite-plagiogranite bodies, in the north border of the Yangtze craton block, adjoining the Qinling orogen, are reported, because its age and genesis are of great importance to research of the tectonic evalutional history for the Qinling orogen and of the rifted processes for the Late Proterozoic supercontinent Rodinia. A good isochron of t=(837±26) Ma (2σ), corresponding to INd=0.51165±2(2σ), εNd(t)=+1.9, MSWD1.02, was difined by the Nd isotopic analytical results for the 21 whole-rock samples from the varied lithological complex bodies, but for the Rb-Sr isotopic aralytical data there is no isochron. The 40Ar/39Ar plateau age of the biotite, sorted from plagiogranites, is (796±20) Ma(2σ), and yet for the Rb-Sr isotopic data of the plagiogranite whole-rock samples (WR) and the sorted biotite (Bio), plagioclase (Plag) and apatite (Apt) mineral samples from the plagiogranitewhole-rock samples, an isochron of t=(824.86±3.8) Ma (2σ) with ISr=0.70393±14(2σ), MSWD2.44 is given. The U-Pb isotopic results for the single zircon, sorted from pla-giogranite samples, yielded an upper and a lower intercept ages of -876 Ma and -273 Ma. The Nd isotope data of complex indicate that it is probably the products of crystallization differentiation from the magma with 3333Nd>0 when the rapid uplift in 837-800 Ma took place in the northern border of the Yangtze craton block.     

Determination of interface (surface) dilatation rheological properties

This note establishes a new method that can measure interface dilatation elastic module (e) and dilatation viscosity (d) of all surfactants based on the surface pressure relaxation process. The wide applicability was proved with the stability of foam as an example.     

颗粒增强不锈钢基复合材料冲蚀磨损性能研究

在MMG－200高温氧化-冲刷腐蚀磨损试验机上,考察了Al     

一个用于有机物生物活(毒)性研究的新拓扑指数

提出一个新的拓扑指数Yx,即隐氢图中的所有相邻边的一阶分子连接性指数的乘积之和占分子中有效碳原子的分率,用Yx研究取代苯,甲基苯、卤代苯、卤代烃、氯苯、含氮杂环化合物和直链伯醇的生物活（毒）性,建立相应的相关方程（r=0.9203-0.9914),计算出部分取代苯类化合物对发光菌（Photobacterium phosphoreum)、呆鲦鱼（Piumephales promelass)、大型蚤（Daphnia magua strau)、酵母菌（Saccharomyces cerevisiae)和绿藻Green algae的毒性数据,新的拓扑指数易于计算,有较高的结构区分能力,新方法计算方便,物理意义明确。