Estimation of Partially Linear Panel Data Models with Cross-Sectional Dependence

Journal of Systems Science and Complexity - This paper studies the estimation of the partially linear panel data models, allowing for cross-sectional dependence through a common factors structure....     

富硒螺旋藻对肝叶切除大鼠肝细胞的抗氧化作用

目的:探讨富硒螺旋藻(Se-SP)对大鼠肝叶切除术后肝细胞的抗氧化效应。方法:采用W istar大鼠复制67%肝切除模型,3个不同剂量组的大鼠于术前连续7 d按每天每公斤体质量灌胃150 mg(H)、50 mg(M)、15 mg(L)的Se-SP,另设生理盐水(P)和假手术(F)对照组。在手术前(0h)及术后12 h和48 h等不同时间点取大鼠肝细胞,检测肝细胞中硒(Se)、脂质过氧化产物丙二醛(MDA)浓度以及谷胱甘肽过氧化物酶(GPx)和超氧化物歧化酶(SOD)活性。结果:与P、F组相比,H、M组肝细胞中Se、GPx和SOD水平均明显升高(P<0.05),MDA水平则明显降低(P<0.05);Se水平与GPx活性呈明显正相关(R2=0.75,P<0.05)而与MDA呈明显负相关(R2=0.70,P<0.05)。结论:Se-SP对肝切除大鼠肝细胞具有良好的抗氧化保护效应,对GPx活性具有明显上调作用。     

GPS软件接收机中C/A码信号捕获的圆周相关算法

采用圆周相关算法实现全球卫星定位系统(GPS)C/A码信号的捕获. 该算法用快速傅立叶变换将输入数据和本地产生的数据变换到频率域, 在频率域进行二者的圆周相关处理, 对相关结果反变换并找到其最大绝对值, 将该值与预先设定的门限值比较, 如果大于门限值, 则信号捕获成功. 圆周相关算法可实现快速获取GPS C/A码信号, 且灵敏度较高.     

基于模型预测控制的轮式移动机器人轨迹规划

针对轮式移动机器人(Wheeled Mobile Robot-WMR)自身欠驱动的特点,并考虑到实际工作时的各种约束和限制,提出了一种基于模型预测控制(Model Predictive Control -MPC)的多约束轨迹规划方法。可以对车体自身的运动学约束、物理约束以及避障等约束进行集中有效的处理,可以生成符合车体自身模型特点并满足各种约束的可行轨迹,充分保证了轮式移动机器人自主行驶的可行性,安全性,高效性。仿真结果充分验证了该方法的有效性。     

基于改进PID神经网络算法的AUV垂直面控制

针对一类小型低速自主水下航行器(AUV)的垂直面运动控制问题,设计了一种改进的PID神经网络控制器,实现对水下航行器在垂直面内深度和俯仰角的全局控制。利用REMUS水下航行器模型搭建了Simulink下AUV垂直面仿真控制系统,仿真结果表明,改进的控制方法克服了原方法中饱和区过大的问题,具有良好的动态性能同时能够适应不同的学习速率和网络初始权重,对水下航行器的工程实际应用具有一定参考价值。     

The Differentiated Effect of Administrative Policy in China's Housing Market——Based on the Heterogeneous Households Multi-Agent Model

Since 2010, Chinese government has introduced a series of administrative policies to limit speculation in the housing market to stabilize price fluctuations and keep the housing market in a healthy state of development. In order to investigate whether administrative policy can play its due role, this paper constructs a comprehensive bottom-up housing market heterogeneous households multiagent model(HHMAM) to undertake research on the differentiated effect of administrative policy in different cities. The empirical studies find that: 1) Administrative policy that increases interest rates will cause housing prices to continue to decline in the long term, but they will resume a rising trend after reaching the lowest point; 2) If the government cancels a property-purchasing limitation, housing prices will continue to rise; and 3) investors tend to invest in 1~(st)-tier cities due to the high demand and greater likelihood of appreciation in these cities.     

雨水管道程序计算与绘图一体化

目前设计部门大多仍采用查图、查表的方法进行雨水管道的水力计算。这种传统的设计计算方法是凭经验进行的方法,费时费力、计算精度不高,不利于设计方案的优化。基于解决传统方法的缺点。应用计算机进行雨水管道的设计计算,并结合绘图软件将计算结果直接标注于图形中。实现程序计算与绘图一体化。     

Application of meshless method to electromagnetic NDT

0 Introduction Finite element methods have been successfully pliedfor solving different kinds of problemsinelectrom netic NDT. The domain under study is divided into mesh of element inthis method.For complicated geom tries or in variable geometry problemsthe mesh present high computational cost due to the reevaluation of e newgeometry. Meshless methods are nowproven as a robust te nique to study field problems in which large geometri deformations areto be modeled,since such methods av the on…     

Vapor-deposited CsPbI3 solar cells demonstrate an efficiency of 16％

Hybrid organic-inorganic perovskite solar cells (PSCs) have made rapid progress in efficiency from 3.8％ to 25.5％ in the past decade [1-3].The hybrid perovskite ...     

Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.