Embryonic development and organogenesis of Chinese giant salamander, Andrias davidianus

The morphology and organogenesis of Chinese giant salamander, Andrias davidianus, in its different developmental periods and stages are described in detail, which provides an intact criterion for distinguishing different stages of its developmental process. Based on the external morphological and internal histological features, six periods including 20 stages of organogenesis of Chinese giant salamander are established, which are cleavage period, blastula period, gastrula period, neurula period, organogenesis stage and hatching stage. Generally, the embryonic development of Chinese giant salamander is consistent with those of Eastern newt, Cynops orientalis, and Black spots frog, R. nigromaculata. However, they have some differences in the early cleavage process and the development of digestive system. The cleavage of Chinese giant salamander, A. davidianus is not a discoidal division type, which is different from other species reported. And the first three cleavages being meridional and a retardant development of its digestive system without halter and sucker existing are the evident features of the embryonic development of Chinese giant salamander.     

Magnetic resonance imaging based volumetry:a primary approach to unravelling the brain

Magnetic resonance(MR)imaging based volumetry is recognized as an important technique for studying the brain.In this review,two principle volumetric methods using high resolution MR images were introduced,namely the Cavalieri method and the voxel based morphometry(VBM).The Cavalieri method represents a manual technique that allows the volume of brain structures to be estimated efficiently with no systematic error or sampling bias,whereby the VBM represents an automated image analysis which involves the use of statistical parametric mapping of the MR imaging data.Both methods have been refined and applied extensively in recent neuro- science research.The present paper aims to describe the development of methodologies and also to update the knowledge of their applica- tions in studying the normal and diseased brain.     

P systems based multi-objective optimization algorithm

Based on P systems, this paper proposes a new multi-objective optimization algorithm (PMOA). Similar to P systems, PMOA has a cell-like structure. The structure is dynamic and its membranes merge and divide at different stages. The key rule of a membrane is the communication rule which is derived from P systems. Mutation rules are important for the algorithm, which has different ranges of mutation in different membranes. The cooperation of the two rules contributes to the diversity of the population, the conquest of the muhimodality of objective function and the convergence of algorithm. Moreover, the unique structure divides the whole population into several sub populations, which decreases the computational complexity. Almost a dozen popular algorithms are compared using several test problems. Simulation results illustrate that the PMOA has the best performance. Its solutions are closer to the true Pareto-optimal front     

Daily variation of carbon flux in soils of Populus euphratica forests in the middle and lower reaches of the Tarim River

In order to lucubrate the daily variation of respiration in soils of Populus euphratica forests and analyze its relationship with environmental factors in the middle and lower reaches of the Tarim River, the LI-8100 instrument of soil CO2 flux system was used to measure the parameters of soil carbon flux and air temperature 10 cm above ground surface along the profiles of Usyman, Archy River, Yengisu and Karday, and the relationships between the soil carbon flux and the soil moisture content were analyzed. The nonlinear regression analysis was carried out with the software SPSS13.0. We observed that: (1) soil respiration began to be restrained when the air temperature was up to 30℃10 cm above the ground surface; (2) the rates of soil respiration under the forests of Populus euphratica were significantly different at various moisture contents, the soil carbon flux was high along the Usyman profile, which has a high soil moisture content, and it was low along the profiles of Archy River, Yengisu and Karday, which has a low soil moisture content; (3) the exponential model can be used to explain the relationship between soil respiration and air temperature 10 cm above the ground surface. The average Q10 values along the profiles of Usyman, Archy River, Yengisu and Karday are 0. 61, 0.16, 0. 22 and 0. 35 respectively, much lower than the average of the world; (4) there is a positive correlation between the soil carbon flux and the soil moisture content.     

Impact of dissolved humic acid on the bioavailability of acenaphthene and chrysene assessed by membrane-based passive samplers

Dissolved organic carbon (DOC) is known to reduce the bioavailability of hydrophobic organic compounds (HOCs) in aqueous environments. This reduction occurs as a result of adsorption to DOC, apparently reducing the freely dissolved concentration of HOCs. In the present study, triolein-embedded cellulose acetate membrane (TECAM) and Japanese medaka (Oryzias latipes) were used to measure the uptake of acenaphthene and chrysene in the presence of commercial humic acid (HA) at different concentrations (0―15 mg C·L-1) under controlled laboratory conditions. Apparent uptake rate constants for PAHs in TECAM and medaka were compared and DOC-water partition coefficients (KDOCs) of two PAHs were calculated with different sampling methods by model fit. Results showed that HA present in water significantly reduced the uptake of PAHs in TECAM and medaka. The obtained values of log KDOC of acenaphthene and chrysene measured by TECAM were 4.63 and 5.83, respectively, whereas biologically determined values were 4.52 and 5.76, respectively. These log KDOC values were comparable to earlier published KDOCs toward commercial HA, thereby indicating that TECAM accumulated only the freely dissolved fraction of chemicals and uptake PAHs in a manner similar to that of fish. All these results suggested that the TECAM method can provide a good means for assessing the impact of DOC on bioavailability of PAHs in the aqueous environment.     

Research on the Bit Computation Model for Time Variable Channel Bandwidth

For the encoding bit-rate problem in H.264 wireless video communication,this paper analyzes the bit-rate computation model and the Mean Square Error distortion model,establishes the relation between the quantization parameter of the encoding bit-rate and the intra frame refresh rate of the macro block,and put forward a new ideal about the coding rate on the basis of general binomial computation model theory. Furthermore,this method not only can adaptively adjust the bit allocation and quantization parameter and prevents buffer from overflowing downward or upward under given network bandwidth,but also can apply the rate-distortion to optimize the solution method,control the encoding bits accurately and optimizes the allocation between the intra and inter frame encoding macro block.     

Investigation of Highly Designable Dented Structures in HP Model with Hydrogen Bond Energy

Some highly designable protein structures have dented on the surface of their native structures, and are not full compactly folded. According to hydrophobic-polar （HP） model the most designable structures are full compactly folded. To investigate the designability of the dented structures, we introduce the hydrogen bond energy in the secondary structures by using the secondary-structure-favored HP model proposed by Ou-yang etc. The result shows that the average designability increases with the strength of the hydrogen bond. The designabilities of the structures with same dented shape increase exponentially with the number of secondary structure sites. The dented structures can have the highest designabilities for a certain value of hydrogen bond energy density.     

The mechanism of HIT/DLR prosthetic hand

A multi-sensory five-fingered prosthetic hand has been designed on the basis of underactuated mechanism and coupling principle. The hand is much similar to the adult hand. Three motors actuate the thumb, the index finger and the other three fingers each. The hand comprises 13 joints. Actuated by a motor, the thumb can move along a conic surface, which is superior in appearance. Driven by another motor with springs as transmission elements, the mid finger, ring finger and little finger can envelop objects with complex shape. The sensory system and the appearance design are introduced. It was verified by experiments that the hand has strong capacity of self adaptation and can accomplish accurate and powerful grasp for objects with complex shape.     

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

Epigenetic silencing in cancer cells is mediated by at least two distinct histone modifications, polycomb-based histone H3 lysine 27 trimethylation (H3K27triM) and H3K9 dimethylation. The relationship between DNA hypermethylation and these histone modifications is not completely understood. Using chromatin immunoprecipitation microarrays (ChIP-chip) in prostate cancer cells compared to normal prostate, we found that up to 5% of promoters (16% CpG islands and 84% non-CpG islands) were enriched with H3K27triM. These genes were silenced specifically in prostate cancer, and those CpG islands affected showed low levels of DNA methylation. Downregulation of the EZH2 histone methyltransferase restored expression of the H3K27triM target genes alone or in synergy with histone deacetylase inhibition, without affecting promoter DNA methylation, and with no effect on the expression of genes silenced by DNA hypermethylation. These data establish EZH2-mediated H3K27triM as a mechanism of tumor-suppressor gene silencing in cancer that is potentially independent of promoter DNA methylation.     

7号信令系统定时服务器设计

在电信领域，尤其在７号信令系统应用中，定时器有决定性的重要影响．以ＴＵＰ为对象，剖析７号信令系统定时特点，分析定时服务器的服务对象和设计需求．基于ＵＮＩＸ和ＶＭＥｅｘｅｃ实时操作系统平台，扩展了标准的ＵＮＩＸ定时服务，提供了一个实时、高分辨率定时处理机制，并从设计方案、实现算法及性能等方面进行了讨论