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771.
拓展高校学报双向展示功能探析   总被引:2,自引:0,他引:2  
随着高等教育和期刊业的改革和发展,高校学报面临着前所未有的机遇和挑战,学报是反映本校教学科研成果的窗口功能定位受到了较大的冲击。学报界有种共识:办学报的目的应该是“提高”而不仅仅是“反映”。因此,应使学报在更好地为本校教学科研服务的同时,也要为整个社会服务,努力拓展学报的双向展示功能:争取校内优稿,提高展示功能的深度;大胆开放办刊,提高展示功能的力度。  相似文献   
772.
CTS及M-CTS与Men+的配位   总被引:1,自引:0,他引:1  
进行了CTS的降解,研究了CTS及M-CTS与Men+的配位.用光谱分析CTS及M-CTS与Men+的配位结果,提出CTS及M—CTS的配位规律.即不同分子量CTS的配位能力,低分子量大于高分子量;不同基团的配位能力:-NH2>>—OH>—C=O不同金属离子与相同分子量的CTS配位,基本遵循与游离氨配位规律.  相似文献   
773.
Hu K  Carroll J  Fedorovich S  Rickman C  Sukhodub A  Davletov B 《Nature》2002,415(6872):646-650
Release of neurotransmitter occurs when synaptic vesicles fuse with the plasma membrane. This neuronal exocytosis is triggered by calcium and requires three SNARE (soluble-N-ethylmaleimide-sensitive factor attachment protein receptors) proteins: synaptobrevin (also known as VAMP) on the synaptic vesicle, and syntaxin and SNAP-25 on the plasma membrane. Neuronal SNARE proteins form a parallel four-helix bundle that is thought to drive the fusion of opposing membranes. As formation of this SNARE complex in solution does not require calcium, it is not clear what function calcium has in triggering SNARE-mediated membrane fusion. We now demonstrate that whereas syntaxin and SNAP-25 in target membranes are freely available for SNARE complex formation, availability of synaptobrevin on synaptic vesicles is very limited. Calcium at micromolar concentrations triggers SNARE complex formation and fusion between synaptic vesicles and reconstituted target membranes. Although calcium does promote interaction of SNARE proteins between opposing membranes, it does not act by releasing synaptobrevin from synaptic vesicle restriction. Rather, our data suggest a mechanism in which calcium-triggered membrane apposition enables syntaxin and SNAP-25 to engage synaptobrevin, leading to membrane fusion.  相似文献   
774.
Integration of telomere sequences with the draft human genome sequence   总被引:15,自引:0,他引:15  
Riethman HC  Xiang Z  Paul S  Morse E  Hu XL  Flint J  Chi HC  Grady DL  Moyzis RK 《Nature》2001,409(6822):948-951
Telomeres are the ends of linear eukaryotic chromosomes. To ensure that no large stretches of uncharacterized DNA remain between the ends of the human working draft sequence and the ends of each chromosome, we would need to connect the sequences of the telomeres to the working draft sequence. But telomeres have an unusual DNA sequence composition and organization that makes them particularly difficult to isolate and analyse. Here we use specialized linear yeast artificial chromosome clones, each carrying a large telomere-terminal fragment of human DNA, to integrate most human telomeres with the working draft sequence. Subtelomeric sequence structure appears to vary widely, mainly as a result of large differences in subtelomeric repeat sequence abundance and organization at individual telomeres. Many subtelomeric regions appear to be gene-rich, matching both known and unknown expressed genes. This indicates that human subtelomeric regions are not simply buffers of nonfunctional 'junk DNA' next to the molecular telomere, but are instead functional parts of the expressed genome.  相似文献   
775.
由于分布式应用的独特性,使得分布式应用程序的调试远比单机应用程序的调试复杂得多。文中对分布式应用程序提出一种“先单机单机程调试,次单机多进程调试,最后再多机远程调试”的调试策略,给出在PowerBuilder开发环境下的实施方法,并对分布式PB应用程序的常用调试工具、技术和调试中应注意的问题进行探讨。所述策略和方法知开发《广西变通高校计算机等级考试管理系统MCT》网络版中得到成功使用,证明是正确可行的。  相似文献   
776.
通过对塔里木盆地前震旦-石炭纪构造演化与地层组合特征的分析研究,将该盆地构造和地层系统划分为2大组合系统5个构造-地层组合.前震旦系为混合片麻岩、浅变质岩组成的地台基底,震旦纪发生板内裂陷形成坳拉槽,早寒武世-奥陶纪和石炭纪是盆地两次大的海侵期,沉积了富含烃类的碳酸盐岩建造,志留-泥盆纪为克拉通边缘隆升阶段,发育浅海相碎屑岩及碳酸盐岩建造.  相似文献   
777.
一种小额支付协议的研究与设计   总被引:4,自引:0,他引:4  
分析了PayWord这种小额支付协议,针对PayWord的一些关于交易原子性的局限性,提出了一种新的支付协议--CertWord,此协议沿用PayWord协议的Payword链来表示货币,充分利用交易证书对交易信息进行签名,并记录交易步骤的状态,从流程上保证交易的原子性。  相似文献   
778.
针对《谈高职院校生源短缺的原因与对策》中描述的 1 4条 ,列举了高职院校在办学规模、专业设置、教育教学改革等方面的成绩 ,从而阐述了与《对策》不同的看法  相似文献   
779.
Bacterial strain PYX-6 that utilizes anthracene,phenanthrene, or pyrene for carbon and energy sources for growth was isolated from a non-polluted lake (Tianchi Lake) in Xinjiang Uygur Autonomous Region of China. Its morphology, physiological and biochemical properties, cell wall pattern and G C mol% content of DNA molecules were characterized. The 16S rRNA gene of strain PYX-6 was sequenced and analyzed for similarities to related bacterial species. Results indicated that strain PYX-6 is a member of the Genus Saccharothrix, and the strain was named Saccha-rothrix sp. PYX-6. When pyrene was the sole carbon source in cultural medium, the strain PYX-6 assimilated pyrene for growth and 0.005% of yeast extract stimulated pyrene degradation and assimilation. The optimal pH of cultural medium and the optimal shaking frequency during cultivation were 6-8 and 200 r/m, respectively. It was found that the disappearance of pyrene in medium occurred before significant growth of strain PYX-6 took place. Phthalic acid, benzylacetic acid, and benzylpropenoic acid were detected as catabolic intermediates during pyrene degradation with mass spectroscopy and this result indicated that Saccharothrix sp.PYX-6 adopted a pathway that is different from the pathway of the previously reported pyrene-degrading Mycobacterium sp. PYR-1.  相似文献   
780.
By mixing various concentrations of poly (ethylene glycol), a series of poly(3,4-ethylenedioxythiophene)-poly(styeenesuffonate) composite thin films were prepared.The electrical conductivity of the PEDOT-PSS/PEG thin films was measured by the four-pcobe method. Experimental results showed that the inclusion of poly(ethylene glycol) influenced the electrical conductivity of PEDOT-PSS film significantly. With the increase of PEG concentrations, the electrical conductivity sharply increased to reach a maximum and then slowly decreased down. Furthermore, the PEG molecular weight and environment temperature also played important roles on the electrical conductivity of PEDOT-PSS/PEG thin films. A good linear relationship was found between in σDC and T^-1/2 within the entire temperature range detected.  相似文献   
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