关于决策支持系统的再认识

本文回顾了决策支持系统(DSS)的发展,指出了所面临的挑战,分析了决策问题的结构,探讨了DSS的定义,着重研究了DSS的进化与进化的DSS,提出了若干新的见解,有助于对DSS的再认识。     

k-半分层空间的注记

本文讨论k-半分层空间与一些其它广义度量空间之间的关系,我们证明了下列定理: (1) k-半分层空间是σ-空间。 (2) Frèchet的k-半分层空间是分层空间。 (3) ortho-紧的k-半分层空间具有σ-闭包保持k-网。 (1)和(2)分别地改进了Heath、Hodel和Lutzer,Foged的结果。(3) 部份地回答了高国士的一个问题。     

Ipr1 gene mediates innate immunity to tuberculosis

An estimated eight million people are infected each year with the pathogen Mycobacterium tuberculosis, and more than two million die annually. Yet only about 10% of those infected develop tuberculosis. Genetic variation within host populations is known to be significant in humans and animals, but the nature of genetic control of host resistance to tuberculosis remains poorly understood. Previously we mapped a new genetic locus on mouse chromosome 1, designated sst1 (for supersusceptibility to tuberculosis 1). Here we show that this locus mediates innate immunity in sst1 congenic mouse strains and identify a candidate gene, Intracellular pathogen resistance 1 (Ipr1), within the sst1 locus. The Ipr1 gene is upregulated in the sst1 resistant macrophages after activation and infection, but it is not expressed in the sst1 susceptible macrophages. Expression of the Ipr1 transgene in the sst1 susceptible macrophages limits the multiplication not only of M. tuberculosis but also of Listeria monocytogenes and switches a cell death pathway of the infected macrophages from necrosis to apoptosis. Our data indicate that the Ipr1 gene product might have a previously undocumented function in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death and pathogenesis.     

非光滑离散Minimax问题的优性充分条件

本文在引入非光滑Lipschitz函数的广义凸性基础上给出了非光滑离散minimax问题的Fritz—Jomn与Kuhn—Tucker充分条件.特别地,也就给出了Lipschitz规划的Fritz—John与Kuhn—Tucker充分条件.本文结论包含或推广了光滑非线性规划与非光滑Lipschitz规划的一系列结论.     

Cooperative Mechanism of Supply Chain Under Asymmetric Information

Abstract: The cooperative mechanism is one main issue in the decentralized supply chain system, especially in an asym-metric information structure. We analyze the non-cooperative game behavior of a 2-echelon distribution supply chain,compare the results with the system optimal solution, and give the supplier dominated cooperative mechanisms. We alsoanalyze the validity of our contract under the asymmetric retailers' holding cost information and give some useful conclu-sions.     

向列相液晶中相位光栅光束耦合特性

为了研究向列相液晶中相位光栅光束耦合特性,从理论上分析了相位光栅的光束耦合和衍射规律,采用掺杂C60垂直排列的向列相液晶(5CB),厚度为20μm的样品,进行二波耦合(TBC)实验,研究动态衍射和光束放大特性。结果表明:相位光栅的衍射强度分布呈现明显不对称。根据取向光折变效应表面电荷调制机制和电场作用下的Carr-Helfrich效应对此现象给出定性解释,认为非对称光强分布来自于样品中产生的非对称相位光栅。液晶中非正弦调制的空间电荷场产生了非对称相位光栅。     

鱼类Ⅱ型抗冻蛋白-冰-水复合体系的理论模拟研究

对鱼类Ⅱ型抗冻蛋白冰晶组成的复合体系在真空条件下进行理论模拟计算的基础上,构建出鱼类Ⅱ型抗冻蛋白冰溶剂(水)的三元复合体系.经过350 ps的动态模拟,研究了溶剂化效应对蛋白冰相互作用体系的影响.通过分子力学及半经验量子力学的计算,进一步研究蛋白与冰晶的相互作用性质,结果表明溶剂化效应具有不容被忽视的重要作用.     

清除血浆中LDL用生物活性短肽SDE的合成研究

高脂血症是引起心脑血管疾病的主要原因之一。Ser-Asp-Glu 三肽(SDE)在对血浆中低密度脂蛋白(LDL)的识别及特异性吸附起关键性作用。本实验采用 DCC/HOBt 液相法,合成三肽(SDE)。重点研究反应温度、反应时间和原料配比对 SDE 产率的影响。结果表明本实验成功合成出SDE 三肽。     

拟幂零等价算子Weyl定理的稳定性

线性算子的谱理论,特别是Hilbert空间上Browder定理和Weyl定理在紧摄动下的稳定性问题是目前研究的热点,本文利用拟幂零等价算子的定义及其之间的关系,研究了它们的Browder定理和Weyl定理在紧摄动下的稳定性,并得出它们的稳定性是等价的.