中国现代时期管理思想的提炼

抗战胜利到中共十一届三中全会召开期间,是中国现代管理思想提炼的时期.代表着中国共产党领导集体智慧的毛泽东思想是中国古往今来最系统、全面、深刻的管理思想,它既有马克思列宁主义的精神,又有中华文化的灵魂,古为今用,洋为中用,集古今优秀管理思想之大成.其代表人物有毛泽东、周恩来、刘少奇和朱德等.     

实时定量PCR检测B细胞恶性肿瘤中BCL11A基因的表达水平

目的:建立B细胞淋巴瘤/白血病BCL11A基因的定量检测方法,并分析其在B细胞恶性肿瘤中的表达水平。方法:利用实时定量RT-PCR分析B细胞淋巴瘤(18例)、B细胞性慢性淋巴细胞白血病(B-CLL,8例)、T细胞性急性淋巴细胞白血病(T-ALL,8例)和正常对照(15例)外周血单个核细胞(PBMC)中BCL11A基因的表达水平,以甘油醛-3-磷酸脱氢酶(GAPDH)基因作为内对照。结果:B-CLL组和B细胞淋巴瘤组患者PBMC中BCL11A表达水平均明显高于正常对照(P=0.000)和T-ALL组(P=0.000);T-ALL组和正常对照组BCL11A表达水平无显著差别(P=0.084);B-CLL组和B细胞淋巴瘤组BCL11A表达水平无显著差别(P=0.776)。在B细胞淋巴瘤不同的病例中,BCL11A表达水平有较大差异,其中最小值为0.04,最大值为9.70,中位值为1.00。结论:成功建立BCL11A基因的定量检测方法。     

预应力CFRP布加固钢筋混凝土梁疲劳性能试验研究

为了研究预应力CFRP布加固钢筋混凝土梁的疲劳性能,进行了4根CFRP布加固的钢筋混凝土和1根对比梁的试验研究.试验中考虑的变量为碳纤维应力强度比、疲劳荷载幅和CFRP布粘贴层数.试验梁采用双点对称等幅、等频率加载.试验结果表明:未加固的对比梁受疲劳荷载作用时,裂缝少而宽;非预应力CFRP布加固梁,裂缝多而密,裂缝高度...     

北斗一号卫星信号高灵敏度捕获方法

研究在复杂环境下弱北斗一号卫星信号的捕获方法.利用北斗一号卫星在同一频率上发射两个波束和帧头与卷尾组成已知连续信息序列的特点,可以对两个波束做长时间相干联合捕获.从增加捕获信号功率和减小非相干累加损失两个方面提高捕获灵敏度.仿真和实测结果表明,联合捕获方法可以捕获低于—133 dBm的信号,性能优于单波束串行搜索捕获方法.     

红外/毫米波复合制导信息处理方法及MPSoC实现

针对共口径红外/毫米波复合制导应用需求,提出一种基于自回归(AR)谱估计和扩展卡尔曼滤波的信息融合处理新方法,基于此方法构建了实现红外/毫米波复合制导信息处理的多处理器片上系统(multiprocessor SoC,MPSoC),该系统采用主/从流水线结构,解决了基于此系统框架的多核通信、系统同步等问题.所提多处理器片上系统在单片FPGA上实现,FPGA实测结果表明,目标融合预测轨迹和真实轨迹基本重合,误差不超过10-2 rad,航向角融合精度远高于毫米波雷达和红外的精度,取得了比较好的融合效果;在100MHz的时钟下,整个红外/毫米波复合制导的信号处理的处理时间不超过2ms,满足复合制导对系统的实时性要求.     

WNXD数据库存储策略的研究和实现

针对NativeXML数据存储性能不高、支持查询和更新效率低等不足,提出一种新的半结构化信息存储模型WNXD。引入动态倒排技术和数据映像机制,将记录和分页的存储模式相结合,建立3种结构化索引,用不同方法解决了结构化和动态增长的矛盾。创建了实用的存储模型,提供了从整体到局部,从元素、属性到具体值的全面覆盖访问策略,底层的数据存取,尤其是内容混杂的各类形式异构数据的有效性和完整性存取,得到了最大程度保证,查询次数减小了I/O,提高了系统处理性能。     

高速铁路运行引发的低频振动的隔振分析

针对传统隔振方法对低频振动无法取得较好效果的问题,分析了波阻块( WIB)和蜂窝形波阻块( HWIB)对高速铁路引发的低频振动的隔振效果.首先建立了列车-路基的数值计算模型,将列车荷载简化为沿路基向前的移动荷载列,并采用基于拉格朗日算法的有限差分软件计算了埋设WIB和HWIB前后场地土的振动情况,最后与空沟的隔振效果进...     

一株产纤维素酶和植酸酶的米曲霉的诱变筛选和固体发酵

通过紫外诱变和微波辐射米曲霉菌株,筛选出高产纤维素酶和植酸酶米曲霉菌株ZQH48,并进行了固体发酵条件的优化.优化后的培养基配方为:菌渣:麸皮=1:1,氯化铵12%,蛋白胨2%,硫酸镁0.07%,氯化钠0.5%,磷酸二氢钾0.02%,固水比为1:1;最佳培养温度35℃.优化后纤维素酶活力可达161.55 U/g,较原始...     

Evaluating the reliability of microsatellite genotyping from low-quality DNA templates with a polynomial distribution model

Molecular studies using trace DNA, such as from museum specimens, ancient or forensic samples and samples obtained noninvasively, often have a common problem of low quality of DNA templates. Amplification errors, such as allelic dropout and false allele, may arise during polymerase chain reaction (PCR) using such samples. A mathematical model which treats homozygotes and heterozygotes discriminately has been developed to measure sample quality and compute the confidence level of using multipletube approaches. We use plucked hair samples collected from 26 individual Sichuan snub-nosed monkeys (Rhinopithecus roxel- lana) to test the model. In this case, a confidence level of 99% can be achieved by three positive PCRs. If the sample quality is very poor and requires many PCR replicates, an alternative multiplestep genotyping method is recommended. This model enables researchers to optimize experimental protocols through pilot studies and obtain reliable genetic information using noninvasive sampling method.     

Aero-optical wavefront measurement technique based on BOS and its applications

A collimated light beam will be refracted if it propagates through a flow-field with index-of-refraction variations,and its wavefront will be distorted.If we measure the deflection angle of the light beam,the gradient of the wavefront can be obtained using the Malus law,and the wavefront aberration can be computed with a reconstruction algorithm.Two characteristics of background oriented schlieren(BOS) are conducive to wavefront aberration measurement:BOS can be used to measure the deflection angle of a light beam by measuring the displacement field between the reference image and the experiment image.Moreover,in a BOS system of Schlieren mode,only the ray perpendicular to the background image can be captured with a camera.This is helpful to measure wavefront aberrations that occur after a planar wavefront has passed through the flow-field.Based on these characteristics of BOS of Schlieren mode,a new wavefront measurement technique,which is called the BOS-based wavefront technique(BOS-WT),is proposed in this paper.It works by constructing the relationship between the displacement of the background image and the aero-optical wavefront gradient and uses the Southwell wavefront reconstruction algorithm.A BOS-WT system was assembled,and its temporal resolution was found to be 6 ns,and its temporal-correlation resolution reached 0.2 μs.A BOS-WT can measure the time-correlation transient wavefront quantitatively.It is simple and easy to operate.In this paper,we also present a study of the aero-optical performance of supersonic mixing layer based on our BOS-WT transient wavefronts at an interval of 5 μs.The results showed the wavefront was transient and distorted after it had passed through the mixing layer.Through the analysis of the data at the 5 μs interval,the temporal evolution of wavefront can be obtained.