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301.
Summary RIA of ecdysones are made on nymphal extracts ofPisaura mirabilis during the intermoulting cycle. The hormone level is low during exuviation and the greatest part of the intermoulting period but increases notably before and after ecdysis. The main hormonal peak or pre-ecdysial peak is due to -ecdysone, characterized by combined TLC/RIA.Acknowledgment. We wish to thank Dr M. Hirn for his help during the manipulations and J. Britton who has translated the text into English. 相似文献
302.
303.
M. D. Adams J. T. Earnhardt B. R. Martin L. S. Harris W. L. Dewey R. K. Razdan 《Cellular and molecular life sciences : CMLS》1977,33(9):1204-1205
Summary Abnormal-8-tetrahydrocannabidiol (ABN-8-THC) failed to elicit central nervous system and cardiovascular effects in laboratory animals. Abnormal-cannabidiol (ABN-CBD) was also devoid of overt behavioral effects but produced marked hypotension with only slight bradycardia in anesthesized dogs.Acknowledgment. This work was supported by NIDA (grant No. DA-00574-01 and DA-00490) and Virginia Heart Society (grant No. RR-05697) 相似文献
304.
R. K. Raina D. Njoroge J. N. Ng'ang'a B. V. Telang 《Cellular and molecular life sciences : CMLS》1977,33(11):1499-1500
Summary
Naja mossambica pallida venom administered i.v. (300 /kg) produces an initial brief fall in blood pressure, due to a direct myocardial depressant effect, and a sustained fall due to central depressant effect.This study was supported by University of Nairobi research grants (670–376). We also thank Mr E. Njogu for photographic assistance. 相似文献
305.
H. -J. Hess J. S. Bindra J. W. Constantine W. Elger O. Loge E. Schillinger W. Losert 《Cellular and molecular life sciences : CMLS》1977,33(8):1076-1077
Summary N-methanesulfonyl 16-phenoxy--tetranor PGE2 is a prostaglandin analog which is markedly more tissue selective than PGE2. This compound is 10–30 times more potent than PGE2 in animal models which are considered relevant to antifertility effects in humans. In pharmacological tests which are believed to be predictive for side effects in humans, the compound has potency either equal to or less than that of PGE2. 相似文献
306.
307.
Molecular analysis of spontaneous somatic mutants. 总被引:17,自引:0,他引:17
Eukaryotic structural gene mutations occurring spontaneously in a mouse myeloma cell line offer the opportunity to study somatic mutation in animal cells at the molecular level. Studies on the myeloma protein and on mRNA have enabled us to characterise four such mutants representing four different mutation mechanisms. The results may have some bearing on the origin of antibody diversity. 相似文献
308.
309.
Migratory birds and homing pigeons can apparently obtain directional information from the Earth's magnetic field. The effect is difficult to detect, and discussion of the possible process of magnetic field detection by birds seems so far to have foundered on the simple fact that the orientational effect of the Earth's magnetic field on a single electron spin associated with a molecule of animal tissue would be of the order 10(-8) eV--almost certainly too small to be detectable biologically. Here I direct attention to a process which would overcome this basic problem, and which also seems to provide an explanation of all the main features of published data. It is a mechanism in principle only, however, and is discussed here in no more detail than is necessary to clarify the basic ideas and to provide a basis for further investigation. 相似文献
310.
An effect which appeared to be pulsating aurora was observed to be associated with explosive releases of barium vapour near 250 km altitude, but only when the explosions were in the path of precipitating electrons associated with the visible aurora. 相似文献