用于无线传感器网络的比例公平队列调度算法

提出了一种适用于无线传感器网络的比例公平队列调度算法,该算法以不同业务类别的平均分组到达率为依据,通过为不同业务类别分配服务配额,在加权轮询调度(WRR)算法的基础上可实现比例公平的平均公组传输时和平均分组丢弃率.由于所提算法仅以不同业务类别的平均分组到达率为依据,无需执行加时间戳、根据时间戳排队等复杂操作,所以更适用于资源受限的无线传感器网络率搭建的实际环境测试发现,当以平均分均传输时延为评价参数时,所提算法可实现比例公平分组传输时延,当所有队列都发生丢弃且以平均分组丢弃率为评价参数时,可实现比例公平的平均分组丢弃率.     

Helium solubility in olivine and implications for high 3He/4He in ocean island basalts

High 3He/4He ratios found in ocean island basalts are the main evidence for the existence of an undegassed mantle reservoir. However, models of helium isotope evolution depend critically on the chemical behaviour of helium during mantle melting. It is generally assumed that helium is strongly enriched in mantle melts relative to uranium and thorium, yet estimates of helium partitioning in mantle minerals have produced conflicting results. Here we present experimental measurements of helium solubility in olivine at atmospheric pressure. Natural and synthetic olivines were equilibrated with a 50% helium atmosphere and analysed by crushing in vacuo followed by melting, and yield a minimum olivine-melt partition coefficient of 0.0025 +/- 0.0005 (s.d.) and a maximum of 0.0060 +/- 0.0007 (s.d.). The results indicate that helium might be more compatible than uranium and thorium during mantle melting and that high 3He/4He ratios can be preserved in depleted residues of melting. A depleted source for high 3He/4He ocean island basalts would resolve the apparent discrepancy in the relative helium concentrations of ocean island and mid-ocean-ridge basalts.     

碱卤晶体赋色仪的设计及运行

提供了激光质量的碱卤色心晶体加质着色用热管仪的设计要点和运行结果。其特点是:1)设计了特殊的‘灯芯’结构,使碱金属的蒸发冷凝区和加色区分开,从而色心的类型、浓度可以精密地加以控制;2)经过予抛光的晶体,经过加色和随后的聚集等过程,可直接装入激光器;3)一次装炉可供多次着色,并能连续操作,可方便地,经济地用来生产激光质量的着色晶体;4)利用DWT-702精密温度控制仪对炉温实现了精密调节,可较为细致地研究加色温度对色心类型、浓度及均匀性的影响。     

多核编程模型运行时环境的自适应性研究

针对多核编程模型运行时环境易造成处理器核资源竞争加剧以及可扩展性较差等弊端,基于动态反馈控制思想,将资源分配、运行时控制、任务执行视为有机整体,提出了自适应协同调度模型ACSM.ACSM采用集中式与分布式相结合的协同机制,动态调节处理器核资源在不同应用负载间及其内部的分配与管理.ACSM的优势在于充分体现了多核编程模型良好的可编程性和可移植性,消除了传统多核运行时环境显式指定核数的弊端,增强了处理器核资源分配的高效性和自适应性.实验结果表明,ACSM在提高多核编程模型易用性的同时,减少了系统处理器核资源的不良竞争,提升了系统的整体性能和资源利用率.与仅依赖多核编程模型运行时环境的调度算法相比,ACSM使应用程序的运行时间缩短了近50%,并且随着应用程序数量的增加效果更加显著.     

组蛋白去乙酰化酶SIRT1:血管性疾病新的潜在治疗靶点

老化是血管性疾病的主要危险因素之一.在老化过程中,内皮功能失调、基质金属蛋白酶调控失常、炎症分子表达增加、氧化应激增加和端粒长度缩短等因素引起了管腔扩张、内膜中层厚度改变等血管结构和僵硬度增加等功能的改变.这些改变使得冠状动脉粥样硬化性心脏病、原发性高血压、脑卒中等与年龄相关的血管性疾病易于发生.因此,抑制年龄相关的分子表达可能是干预血管性疾病的有效途径.哺乳动物SIRT1是一种NAD+依赖的组蛋白去乙酰化酶.近年来,对于SIRT1在血管性疾病中的作用受到广泛关注.本文结合我们的研究,阐述了SIRT1在血管老化及相关疾病中的作用,并提出SIRT1可能成为治疗动脉粥样硬化等年龄相关血管性疾病的潜在靶点.     

传感器网络基于邻居信息量化的能量平衡路由

针对地理位置路由中数据包的平均传输能耗随时间推移急剧增加的问题,设计并实现了一种基于两跳邻居信息量化的能量平衡路由协议(TNEB).节点通过Hello报文获得两跳范围内的邻居节点信息,TNEB根据两跳邻居信息确定一个贪婪转发候选节点集合.依据邻居节点的数据流拥塞度和能量平衡度,从候选节点集合中选择最佳的邻居节点完成数据包的转发.测试结果表明,在平均邻居节点数为15的网络拓扑上,TNEB算法的平均能耗比Greedy-2和GPSR算法分别降低了26.7％和48.8％,端到端延迟分别减少了19.9％和31.8％.     

Flagellar motility is required for the viability of the bloodstream trypanosome

The 9 + 2 microtubule axoneme of flagella and cilia represents one of the most iconic structures built by eukaryotic cells and organisms. Both unity and diversity are present among cilia and flagella on the evolutionary as well as the developmental scale. Some cilia are motile, whereas others function as sensory organelles and can variously possess 9 + 2 and 9 + 0 axonemes and other associated structures. How such unity and diversity are reflected in molecular repertoires is unclear. The flagellated protozoan parasite Trypanosoma brucei is endemic in sub-Saharan Africa, causing devastating disease in humans and other animals. There is little hope of a vaccine for African sleeping sickness and a desperate need for modern drug therapies. Here we present a detailed proteomic analysis of the trypanosome flagellum. RNA interference (RNAi)-based interrogation of this proteome provides functional insights into human ciliary diseases and establishes that flagellar function is essential to the bloodstream-form trypanosome. We show that RNAi-mediated ablation of various proteins identified in the trypanosome flagellar proteome leads to a rapid and marked failure of cytokinesis in bloodstream-form (but not procyclic insect-form) trypanosomes, suggesting that impairment of flagellar function may provide a method of disease control. A postgenomic meta-analysis, comparing the evolutionarily ancient trypanosome with other eukaryotes including humans, identifies numerous trypanosome-specific flagellar proteins, suggesting new avenues for selective intervention.