316L不锈钢表面纳米化残余应力对材料性能的影响

高速旋转丝表面纳米化是一种新型的表面纳米化方法,本文对316L不锈钢表面进行纳米化处理,测定残余应力在材料内部的分布.通过分析、对比实验数据,表面纳米化处理方法,能够在材料内部引入大量残余压应力,提升材料的力学性能.     

浅谈既有建筑物加层方法选择及存在问题

随着我国当前人口增长速度加快、国内用地日益紧张,我国开始加强了对既有建筑加层改造研究与探讨的重视。文章简要介绍了常用的一些加层方法及加层后建筑较加层前所发生的变化,阐述了国内外当前发展状况及研究现状,探讨了当前在加层研究中存在的问题。     

工业源挥发性有机物治理功能材料研究进展

挥发性有机物(volatile organic compounds,VOCs)是大气中一类重要的污染物质,即使在低浓度下也会对人类的健康造成威胁。对VOCs的治理刻不容缓,而VOCs治理关键功能材料性能的优劣是整个VOCs治理技术的核心。文章总结了近年来用于吸附法、光催化法以及催化燃烧法治理VOCs的功能材料的最新科研成果,希望以此能够为将来VOCs治理材料的设计与研发提供一定的参考。     

Study on the fusion emotion classification of multiple characteristics based on attention mechanism

The current research on emotional classification uses many methods that combine the attention mechanism with neural networks.However,the effect is unsatisfactory when dealing with complex text.An emotional classification model is proposed,which combines multi-head attention(MHA)with improved structured-self attention(SSA).The model makes several different linear transformations of input by introducing MHA mechanism and can extract more comprehensive high-level phrase representation features from the word embedded vector.Meanwhile,it can realize the parallelization calculation and ensure the training speed of the model.The improved SSA structure uses matrices to represent different parts of a sentence to extract local key information,to ensure that the degree of dependence between words is not affected by time and sentence length,and generate the overall semantics of the sentence.Experiment results show that the current model effectively obtains global structural information and improves classification accuracy.     

基于物体关系描述的单目语义SLAM方法

外界环境的语义感知和自身位置的准确估计是移动机器人自主导航和作业的关键。提出了一种基于单目相机的语义SLAM(simultaneous localization and mapping)方法,在轨迹估计的同时完成三维目标检测。提取物体自身语义、尺寸、颜色分布及其邻域拓扑结构等多元信息作为描述子,实现帧间物体的准确关联。在后端对相机位姿、地图点和物体路标进行联合优化,并自适应调整代价函数中各误差项的权重系数,以提高各状态变量的估计精度和鲁棒性。实验结果表明,所提出的算法在地图构建方面具有较高的精度。     

可逆计算原理与实验进展

计算能耗高和散热问题使传统计算芯片的集成度和运算能力的提升遇到瓶颈.大规模量子计算探索的关键是比特的相干叠加性和可逆性.因此,可逆计算既作为一种可能从根本上解决计算耗能高和散热问题的方案,又作为一种兼容量子计算的方案,近年来在理论上和实验上得到了深入的研究.本文介绍了可逆计算的基本原理,总结了目前基于微机械、传统微电子和超导领域的可逆计算实验研究进展,分析了超导器件实现可逆计算的独特优势,并着重对其中两种器件的工作原理进行了论述.     

MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

Disruption of signaling pathways such as those mediated by sonic hedgehog (Shh) or platelet-derived growth factor (Pdgf) causes craniofacial abnormalities, including cleft palate. The role that microRNAs play in modulating palatogenesis, however, is completely unknown. We show that, in zebrafish, the microRNA Mirn140 negatively regulates Pdgf signaling during palatal development, and we provide a mechanism for how disruption of Pdgf signaling causes palatal clefting. The pdgf receptor alpha (pdgfra) 3' UTR contained a Mirn140 binding site functioning in the negative regulation of Pdgfra protein levels in vivo. pdgfra mutants and Mirn140-injected embryos shared a range of facial defects, including clefting of the crest-derived cartilages that develop in the roof of the larval mouth. Concomitantly, the oral ectoderm beneath where these cartilages develop lost pitx2 and shha expression. Mirn140 modulated Pdgf-mediated attraction of cranial neural crest cells to the oral ectoderm, where crest-derived signals were necessary for oral ectodermal gene expression. Mirn140 loss of function elevated Pdgfra protein levels, altered palatal shape and caused neural crest cells to accumulate around the optic stalk, a source of the ligand Pdgfaa. These results suggest that the conserved regulatory interactions of mirn140 and pdgfra define an ancient mechanism of palatogenesis, and they provide candidate genes for cleft palate.     

基于自注意力机制的科技术语自动提取技术研究

科技术语提取是科技术语自动处理的重要环节,对后续的机器翻译、信息检索、QA问答等任务有重要意义.传统的人工科技术语提取方法耗费大量的人力成本.而一种自动提取科技术语方法是将术语提取转化为序列标注问题,通过监督学习方法训练出标注模型,但是面临缺乏大规模科技术语标注语料库的问题.文章引入远程监督的方法来产生大规模训练标注语...     

The emerging link between O-GlcNAcylation and neurological disorders

O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is involved in the regulation of many cellular cascades and neurological diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and stroke. In the brain, the expression of O-GlcNAcylation is notably heightened, as is that of O-linked N-acetylglucosaminyltransferase (OGT) and β-N-acetylglucosaminidase (OGA), the presence of which is prominent in many regions of neurological importance. Most importantly, O-GlcNAcylation is believed to contribute to the normal functioning of neurons; conversely, its dysregulation participates in the pathogenesis of neurological disorders. In neurodegenerative diseases, O-GlcNAcylation of the brain’s key proteins, such as tau and amyloid-β, interacts with their phosphorylation, thereby triggering the formation of neurofibrillary tangles and amyloid plaques. An increase of O-GlcNAcylation by pharmacological intervention prevents neuronal loss. Additionally, O-GlcNAcylation is stress sensitive, and its elevation is cytoprotective. Increased O-GlcNAcylation ameliorated brain damage in victims of both trauma-hemorrhage and stroke. In this review, we summarize the current understanding of O-GlcNAcylation’s physiological and pathological roles in the nervous system and provide a foundation for development of a therapeutic strategy for neurological disorders.     

过江隧道穿越既有铁路相互影响研究

过江隧道穿越既有铁路的相互影响是一个难点.依托重庆长江隧道穿越襄渝铁路工程进行研究,研究结果表明：过江隧道施工对既有铁路两个方向地表沉降的影响都很小,最大值为2.549 mm,故受影响的既有铁路附近地层不需做特殊加固处理,但要加强监控;既有铁路对过江隧道结构安全性及洞周位移影响也较小,在列车荷载作用下结构最小安全系数为6.8,过江隧道结构仍是偏于安全的,故隧道结构可不作加固处理,只需加强监控.研究成果为保证既有铁路的正常运营及过江隧道的结构安全性提供了理论基础,并可为相似工程提供参考.