不确定性决策中完全信息获得的事前分析

明确了规范决策分析中信息的概念,介绍了信息获得与否的价值判断法。然后主要针对不确定性决策完全信息获得的事前分析进行了讨论,给出了单状态完全信息获得的概念和一个实际分析例子;同时对完全信息与风险态度的关系进行了简单的分析。     

可编程的VXI总线消息基接口芯片设计与实现

本文介绍了用大规模可编程逻辑器件设计和实现ＶＸＩ总线消息基接口芯片。该接口芯片具有中断ＲＯＲＡ、Ａ１６／Ｄ１６、Ａ２４／Ｄ３２及块传输能力,传输速率高达２０ＭＢ／ｓ。由于采用可重配置可编程逻辑器件,故很易实现ＶＸＩ总线Ａ３２／Ｄ３２的能力。     

White noise estimation for discrete-time systems with random delay and packet dropout

This paper is concerned with the optimal and suboptimal deconvolution problems for discrete-time systems with random delayed observations. When the random delay is known online, i.e., time stamped, the random delayed system is reconstructed as an equivalent delay-free one by using measurement reorganization technique, and then an optimal input white noise estimator is presented based on the stochastic Kahnan filtering theory. However, tb_e optimal white-noise estimator is timevarying, stochastic, and doesn＇t converge to a steady state in general. Then an alternative suboptimal input white-noise estimator with deterministic gains is developed under a new criteria. The estimator gain and its respective error covariance-matrix information are derived based on a new suboptimal state estimator. It can be shown that the suboptimal input white-noise estimator converges to a steady-state one under appropriate assumptions.     

休闲视角下哈大齐城市群体育社团发展研究

运用文献资料、问卷调查、访谈、数理统计和逻辑分析等调查方法,对哈大齐城市群体育社团的发展概况、形成时间、注册情况、体育社团负责人情况、办公场所及活动场地设施情况、组织活动、经费来源渠道等方面的现状进行了详细的调查研究.在此基础上分析哈大齐城市群体育社团发展的优势以及面临的困难和需要解决的问题,并借鉴国内外社团发展经验,提出相应的意见和建议,为体育社团在黑龙江省更好地发展提供理论参考依据.     

浅谈水泥稳定碎石基层的质量控制

通过对基层的设计、试验、施工等各个环节的控制，提高水泥稳定碎石基层的强度，控制其裂缝的产生，从而保证工程质量。     

瞬变电磁法在一四井煤矿采空区探测中的应用

采用瞬变电磁法(TEM)在河南省新密市境内探查一四井煤矿采空区积水分布情况、断层等构造的含导水性情况及二1煤底板的富水性情况,为矿井防治水工作的合理实施提供依据.     

超高性能混凝土组合桥面板集群化短焊钉抗疲劳特性

进行4个单钉和2个群钉疲劳推出试验,将短焊钉疲劳寿命与国内外规范中的焊钉S-N曲线进行比较,并结合塑性损伤有限元模型展开分析。结果表明：短焊钉疲劳破坏表现为根部剪断和周围超高性能混凝土（UHPC）局部压溃;集群化短焊钉疲劳寿命较单钉减少26.9%,在疲劳加载过程中抗剪刚度退化显著快于单钉,当加载次数达到疲劳寿命的12.0%附近时,抗剪刚度比减小至16%左右;AASHTO规范有较大的安全储备,相比之下日本规范（JSCE）与试验结果最为接近,安全富余较少。此外,疲劳荷载下集群化短焊钉根部循环应变幅大于单钉,而且周边UHPC的塑性损伤累积分布更大。     

基于烟花算法的基站群协作计算卸载模型研究

车联网、AR、AI等计算密集、时延敏感型应用迅速发展,而移动设备因自身计算能力相对不足,执行此类应用任务时会因高时延而严重影响用户体验甚至无法满足用户需求。针对此问题,提出综合考虑时延与成本的多用户、多MEC (mobile edge computing)服务器的基站群协作计算卸载模型。并提出基于凸优化的改进烟花算法（improved fireworks algorithm based on convex optimization, CVX-FWA）来对模型进行求解,对用户任务进行合理的卸载与资源分配。仿真结果表明,提出的计算卸载方案有效降低了任务总时延成本值,实现计算卸载资源的整体优化配置。     

BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β

Reduced hepatic expression levels of bromodomain-containing protein 7 (BRD7) have been suggested to play a role in the development of glucose intolerance in obesity. However, the molecular mechanism by which BRD7 regulates glucose metabolism has remained unclear. Here, we show that BRD7 increases phosphorylation of glycogen synthase kinase 3β (GSK3β) in response to activation of the insulin receptor-signaling pathway shortly after insulin stimulation and the nutrient-sensing pathway after feeding. BRD7 mediates phosphorylation of GSK3β at the Serine 9 residue and this effect on GSK3β occurs even in the absence of AKT activity. Using both in vitro and in vivo models, we further demonstrate that BRD7 mediates phosphorylation of ribosomal protein S6 kinase (S6K) and leads to increased phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) and, therefore, relieves its inhibition of the eukaryotic translation initiation factor 4E (eIF4E). However, the increase in phosphorylation of 4E-BP1 with BRD7 overexpression is blunted in the absence of AKT activity. In addition, using liver-specific BRD7 knockout (LBKO) mice, we show that BRD7 is required for mTORC1 activity on its downstream molecules. These findings show a novel basis for understanding the molecular dynamics of glucose metabolism and suggest the unique function of BRD7 in the regulation of glucose homeostasis.