Functional consequences of treating turkey liver fructose-1,6-bisphosphatase with penicillin G

Summary Treatment of turkey liver fructose-1,6-bisphosphatase with penicillin G progressively inactivated the enzyme and desensitized the enzyme toward high substrate inhibition. The treatment also led to reduced sensitivity to AMP inhibition and the loss of cooperative interaction among AMP-binding sites. These altered properties were not reversed by dialysis, but were prevented when treatment with penicillin G was performed in the presence of substrate.This work was in part supported by grant RR-8006 from the General Research Branch, Division of Research Resources, NIH (USA) and in part by Faculty Research Grant from Southern School of Pharmacy, Mercer University, Atlanta (Georgia, USA).     

弹性钻柱两个特殊点的意义及计算方法

通过分析钻柱的应力和应变状态,对钻柱的中性点和零轴向力点给出了新的定义和计算方法,并阐述了稳定力和屈曲力(通称为虚轴向力)的概念。导出了处在垂直井眼中的复合钻柱的有关计算公式。文中还与原有的研究结论进行了对比分析,并提出了不同意见。本文以钻柱为研究对象,所得的结果可以推广应用到套管柱及油管柱上。     

Cellular responses to mild heat stress

Since its discovery in 1962 by Ritossa, the heat shock response has been extensively studied by a number of investigators to understand the molecular mechanism underlying the cellular response to heat stress. The most well characterized heat shock response is induction of the heat shock proteins that function as molecular chaperones and exert cell cycle regulatory and anti-apoptotic activities. While most investigators have focused their studies on the toxic effects of heat stress in organisms such as severe heat stress-induced cell cycle arrest and apoptosis, the cellular response to fever-ranged mild heat stress has been rather underestimated. However, the cellular response to mild heat stress is likely to be more important in a physiological sense than that to severe heat stress because the body temperature of homeothermic animals increases by only 1–2°C during febrile diseases. Here we provide information that mild heat stress does have some beneficial role in organisms via positively regulating cell proliferation and differentiation, and immune response in mammalian cells.Received 14 May 2004; received after revision 2 August 2004; accepted 16 August 2004     

Culinary archaeology: Millet noodles in Late Neolithic China

Noodles have been a popular staple food in many parts of the world for at least 2,000 years, although it is debatable whether the Chinese, the Italians or the Arabs invented them first. Here we analyse a prehistoric sample of noodles contained in a well preserved, sealed earthenware bowl discovered in the Late Neolithic archaeological site of Lajia in northwestern China. We identify millet as the source of the abundant seed-husk phytoliths and starch grains present in the vessel. This shows that the conversion of ground millet flour into dough that could be repeatedly stretched into long, thin strands for the preparation of boiled noodles was already established in this region 4,000 years ago.     

Strategies of delayed self-pollination in <Emphasis Type="Italic">Kosteletzkya virginica</Emphasis>

Though in the face of selection against self-pollination, mixed pollination systems are maintained in many plants. The transition from outcrossing to self-fertilization is one of the most common evolutionary trends in angiosperms . Floral morphological characters and behavior influence plant pollination mode and reproductive success,     

《诗词鉴赏与习作》课教学琐谈

在高校开设传统诗词鉴赏与习作课程不仅能陶冶学生情操,拓展学生知识视野,同时也能提高学生的学习兴趣与创造能力。本文从三方面探讨了高校诗词课教学的几个问题。     

风险投资能筛选并培育优质企业吗?——基于中国创业板的模糊断点回归分析

风险投资（venture capital，简称VC）能否筛选出优质企业进行投资并促进被投企业的业绩改善，是判断新兴市场国家风险投资行业是否成熟的一个重要标志.对于这一问题，针对国内市场的研究匮乏.本文以中国创业板上市企业为研究样本，研究VC能否筛选出优质企业以及能否为被投企业带来业绩改善，并进一步探讨其作用机制.研究发现：1）基于逻辑回归，VC未必能筛选出优质的企业，表现为企业业绩变量回归系数不显著；2）基于模糊断点回归进行内生性调整后，VC能够促进被投企业的发展，对被投企业的业绩改善有正向作用；3）从经营效益和创新角度研究VC影响企业业绩的潜在机制发现：一方面，VC降低了被投企业的销售成本率，提高了企业的经营效益；另一方面，VC的进入为被投企业带来行业经验和资源等，促进被投企业技术或商业模式的创新，从而有助于改善企业的经营业绩.本文实证结果表明国内VC具有"增值"作用，能够创造经济价值，但不具有"筛选"作用，揭示了VC对被投企业业绩的影响及潜在作用机制，为VC能促进被投企业的发展提供了新的实证参考.研究结果对于企业、风险投资机构和政策制定者具有借鉴意义和参考价值.     

金属薄膜与萃取复型电镜照片上测量球状第二相误差分析

本文通过理论和实验数据分析表明:在萃取复型和金属薄膜电镜照片上定量测量球状第二相的加权平均直径时,存在较大误差。文章同时给出了两种误差的大小和它们之间的关系。     

水压爆破装药量的新探索

通过对不同材质的容器，用不同数量炸药进行水压爆破实验，观测容器材质对装药量的影响，探索水压爆破所需药量与材料的物理力学性质──密度ρ和抗拉强度Ｒ拉之间的关系，从而确定在一定水压爆破条件下新药量公式中的爆破强度系数Ｋ２。