A high-resolution map of human chromosome 12

Our sequence-tagged site-content map of chromosome 12 is now integrated with the whole-genome fingerprinting effort. It provides accurate and nearly complete bacterial clone coverage of chromosome 12. We propose that this integrated mapping protocol serves as a model for constructing physical maps for entire genomes.     

Induced recovery of defective membrane expression of a CC chemokine receptor 5 mutant by phytohemagglutinin

CC chemokine receptor 5 (CCR5) is a member of the G-protein-coupled receptor superfamily. It plays an important role in macrophage tropic human immunodeficiency virus-1 entry and in some inflammatory reactions. CCR5-893(–) is a single-nucleotide deletion that results in complete truncation of the C tail of the gene product. We detected CCR5-893(–) in a sample of patients infected with non-tuberculosis mycobacteria and found that it was maintained heterozygously with a frequency of 2%. There is no association between this mutation and any immunodeficiency. Membrane expression of CCR5-893(–) was substantially reduced compared to the wild type, but this defective surface presentation recovered greatly recovered in the presence of 2 mg l-1 phytohemagglutinin (PHA). However, PHA inducement did not affect the total intracellular expression of CCR5-893(–) or wild-type CCR5. Thus we suggest there exist some PHA-induced factor(s) that could mediate the presentation of truncated CCR5.Received 23 July 2003; accepted 18 August 2003     

Rotational actuators based on carbon nanotubes

Nanostructures are of great interest not only for their basic scientific richness, but also because they have the potential to revolutionize critical technologies. The miniaturization of electronic devices over the past century has profoundly affected human communication, computation, manufacturing and transportation systems. True molecular-scale electronic devices are now emerging that set the stage for future integrated nanoelectronics. Recently, there have been dramatic parallel advances in the miniaturization of mechanical and electromechanical devices. Commercial microelectromechanical systems now reach the submillimetre to micrometre size scale, and there is intense interest in the creation of next-generation synthetic nanometre-scale electromechanical systems. We report on the construction and successful operation of a fully synthetic nanoscale electromechanical actuator incorporating a rotatable metal plate, with a multi-walled carbon nanotube serving as the key motion-enabling element.     

Experimental investigation of parallel optical data storage using pyrrylfulgide photochromic material

The optical storage characteristics of a new kind of organic photochromic material棗pyrrylfulgide were experimentally investigated in the established parallel optical data storage system. Using the pyrrylfulgide/PMMA film as a photon-mode recording medium, micro-images and encoded binary digital data were recorded, readout and erased in this parallel system. The storage density currently reaches 3?107 bit/cm2. The recorded information on the film can be kept for years in darkness at room temperature.     

Climate as the dominant control on C<Subscript>3</Subscript> and C<Subscript>4</Subscript> plant abundance in the Loess Plateau: Organic carbon isotope evidence from the last glacial-interglacial loess-soil sequences

Two modes of photosynthesis predominate in terres-REPORTS trial plants: the C3 and C4 modes[1]. The C3 mode is used by all of trees, bushes, and cold season grasses. The C4 mode is used by the most of tropical and warm season grasses. They are disadvantaged relative to C3 plants at high CO2/O2 ratios because of the additional energy ex-pense needed to concentrate CO2 in the bundle-sheath cells. At low CO2/O2, however, C4 plants can achieve a relatively high quantum yield by suppressin…     

超稳Y-沸石催化合成乙酰乙酸乙酯缩酮

用脱铝超稳Ｙ－沸石作催化剂合成了乙酰乙酸乙酯与乙二醇缩酮和丙二醇缩酮,其产率可达到８０％和９６％,考察了催化剂组成和反应时间对反应的影响规律,发现产物比反应物更易在催化剂表面吸附,对反应机理作了讨论。     

The mean free path for electron conduction in metallic fullerenes

The electrical resistivity, p, of a metal is usually interpreted in terms of the mean free path (the average distance, l, an electron travels before it is scattered). As the temperature is raised, the resistivity increases and the apparent mean free path is correspondingly reduced. In this semi-classical picture, the mean free path cannot be much shorter than the distance, d, between two atoms. This has been confirmed for many systems and was considered to be a universal behaviour. Recently, some apparent exceptions were found, including alkali-doped fullerenes and high-temperature superconductors. However, there remains the possibility that these systems are in exotic states, with only a small fraction of the conduction electrons contributing to the conductivity; the mean free path would then have to be correspondingly larger to explain the observed resistivity. Here we report a model calculation of electron conduction in alkali-doped fullerenes, in which the electrons are scattered by intramolecular vibrations. The resistivity at large temperatures implies l < d, demonstrating that there is no fundamental principle requiring l > or = d. At high temperatures, the semi-classical picture breaks down, and the electrons cannot be described as quasiparticles.     

木果楝挥发油成分的GC-MS分析

采用气相色谱-质谱联用技术,首次对木果楝叶子和果实挥发油进行了成分分析,从木果楝叶子和果实分别鉴定出了33和36种化合物,分别占挥发油的99.11%和97.63%.两个部位中挥发油化学组成各有异同,但其主要成分均是倍半萜类化合物b-桉叶烯和γ-桉叶烯.本研究结果可为木果楝的综合开发利用提供理论依据.     

一种多路聚合型CICOQ交换结构

提出了一种多路聚合型联合输入/交叉节点/输出排队(CICOQ)交换结构,并从理论上证明了当聚合路数等于2时,多路聚合型CICOQ交换结构无需加速即可通过分布式调度算法实现模拟采用任意调度算法的输出排队交换结构。最后从实现的角度给出了多路聚合型CICOQ交换结构的工程设计方案,并通过仿真对该方案的性能进行了验证。