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421.
对—氯片呐酮与1,2,4—三唑缩合为1—(1,2,4—三唑基—1) —片呐酮时的分子比、溶剂、缚酸剂、反应时间等条件进行了研究,得到一种适合放大应用于工业生产的以乙醇为溶剂的最佳缩合条件。 相似文献
422.
Dr. Kye-Chang Ko R. R. Paradise Dae-Sup Han 《Cellular and molecular life sciences : CMLS》1972,28(12):1466-1468
Zusammenfassung Die nach Halothan eingetretene Verminderung der Kontraktilität des Myokards kann durch Pyruvat verhindert werden. Dieses Ergebnis stützt die Hypothese. Halothan behindere die Aufnahme oder die Verwertung von Glycose. 相似文献
423.
424.
Evidence for dynamically organized modularity in the yeast protein-protein interaction network 总被引:1,自引:0,他引:1
Han JD Bertin N Hao T Goldberg DS Berriz GF Zhang LV Dupuy D Walhout AJ Cusick ME Roth FP Vidal M 《Nature》2004,430(6995):88-93
In apparently scale-free protein-protein interaction networks, or 'interactome' networks, most proteins interact with few partners, whereas a small but significant proportion of proteins, the 'hubs', interact with many partners. Both biological and non-biological scale-free networks are particularly resistant to random node removal but are extremely sensitive to the targeted removal of hubs. A link between the potential scale-free topology of interactome networks and genetic robustness seems to exist, because knockouts of yeast genes encoding hubs are approximately threefold more likely to confer lethality than those of non-hubs. Here we investigate how hubs might contribute to robustness and other cellular properties for protein-protein interactions dynamically regulated both in time and in space. We uncovered two types of hub: 'party' hubs, which interact with most of their partners simultaneously, and 'date' hubs, which bind their different partners at different times or locations. Both in silico studies of network connectivity and genetic interactions described in vivo support a model of organized modularity in which date hubs organize the proteome, connecting biological processes--or modules--to each other, whereas party hubs function inside modules. 相似文献
425.
ZHUDa MAZhongyuan MEIJiaxin HANPeigao HUANGXinfan CHENKenji 《科学通报(英文版)》2004,49(18):1906-1910
A series of hydrogen-containing a-Si:H/SiO2 multilayers with different a-Si:H sublayer thickness were fabricated by layer-by-layer deposition and in situ plasma oxidation in a plasma-enhanced chemical vapor deposition system (PECVD). Optical induced blue emission from the samples was observed by the naked eye at room temperature, which has never been reported in the luminescence study of Si/SiO2 multilayers up to now. Both the photoluminescence (PL) peak and the absorption edge show a blue shift as the a-Si:H sublayer thickness decreases. The origin of the blue emission and the effect of hydrogen are discussed. 相似文献
426.
Vissers LE van Ravenswaaij CM Admiraal R Hurst JA de Vries BB Janssen IM van der Vliet WA Huys EH de Jong PJ Hamel BC Schoenmakers EF Brunner HG Veltman JA van Kessel AG 《Nature genetics》2004,36(9):955-957
CHARGE syndrome is a common cause of congenital anomalies affecting several tissues in a nonrandom fashion. We report a 2.3-Mb de novo overlapping microdeletion on chromosome 8q12 identified by array comparative genomic hybridization in two individuals with CHARGE syndrome. Sequence analysis of genes located in this region detected mutations in the gene CHD7 in 10 of 17 individuals with CHARGE syndrome without microdeletions, accounting for the disease in most affected individuals. 相似文献
427.
428.
Han Xiao-fang Zheng Lian-shuang Xie Yi-min . Department of Chemical Engineering Wuhan University of Technology Wuhan Hubei China . College of Chemical Environmental Engineering Jianghan University Wuhan Hubei China . The State Key Laboratory of Pulp Paper Engineering South China University of Technology Guangzhou Guangdong China 《武汉大学学报:自然科学英文版》2004,9(1):125-128
Xylanisthemajorcomponentofplantcellwallsandthemostabundantpentosaninnature.Xylancontainsβ 1,4 linkedd xylosebackboneswitharabinose,4 O methyl d glucuronicacid,andaceticacidsubstituents[1 ] .Thexylan degradingen zymesincludeendoxylanase(1,4 β d xylanxylanohydrolase;EC3.2 .1.8)and β xylosidase (1,4 β d xylanxylanohydrolase;EC 3.2 .1.37) .xylanasedegradesthexylanbackboneintoxylo bioseandxylooligosaccharides,whileβ xylosidasereleasesxylosylresiduesfromthenonreducingendsofxylooligosaccha… 相似文献
429.
HANLu ZHOUMan-li TIANJing KURTRothermel 《武汉大学学报:自然科学英文版》2004,9(6):931-934
A new algorithm called spatially aware routing algorithm with enhanced learning (SAREL) is proposed to guarantee the rationality of route selecting in inter-vehicle communication scenario. Firstly, the traffic model is discussed and set up by using Poisson distribution. Then we analyze the process of traffic evaluation with enhanced learning, and exploit movement estimation to assist state memorization. The improvement of algorithm is provided at last compared with our previous work. Simulation results show that SAREL algorithm could achieve better performance in packet delivery ratio, especially when network connection ratio is average. 相似文献
430.