非标准设备驱动程序与微机DOS的接口

阐述了一种与ＤＯＳ接口的非标准设备驱动程序的编程方法，它增加了非标准设备驱动程序的适用性．     

冀东褐土区花生施用石膏研究初报

在冀东褐土区花生田间施用石膏，对花生经济性状和植株各部位钙、镁含量有明显影响，并显著提高花生产量。石膏经济最佳施用量和最高产量施用量分别为３５８．９ｋｇ／ｈｍ２和３８６．０ｋｇ／ｈｍ２，经济合理施用量为３３１．５８～３４５．３５ｋｇ／ｈｍ２，在此范围内，花生增产１９．０６％～１９．２３％。     

残留碳化物在等温球化处理中的作用

本文研究了5种钢在等温球化处理中残留碳化物的分布形态（数量、有效尺寸、弥散度、形状）的作用，结果表明，残留碳化物的有效尺寸越小，数目越多，形状为圆形时，效果较为理想。经过电子显微镜、金相显微镜以及理论上的分析，证实了点状残留碳化物起的作用为：使碳化物以短棒状和颗粒状析出，为以后碳化物长大做好准备，同时，本文还制定了GCr15和T12最佳的等温球化工艺。     

用图解解析法进行运动平面三个有限近位置的机构综合

本文用图解解析方法．建立了极点、镜像点和等角反向规律的数学模型；解决了运动平面三个有限接近位置机构综合的计算机辅助设计问题，并附有计算程序框图和工程设计实例．     

邻氨基噻唑偶氮类试剂质子化机理的研究

邻氨基噻唑偶氮类试剂［１～３］在不同酸度下呈现不同的颜色,关于其质子化发生的位置以及先后次序至今尚未见文献报道．本文通过量子化学计算,结合分光光度法对这类试剂质子化行为进行了研究．１实验方法１．１吸收光谱测定移取１．０ｍＬ１．０×１０－３ｍｏｌ／ＬＴ...     

Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome

Protein-protein interaction analyses have uncovered a ciliary and basal body protein network that, when disrupted, can result in nephronophthisis (NPHP), Leber congenital amaurosis, Senior-L?ken syndrome (SLSN) or Joubert syndrome (JBTS). However, details of the molecular mechanisms underlying these disorders remain poorly understood. RPGRIP1-like protein (RPGRIP1L) is a homolog of RPGRIP1 (RPGR-interacting protein 1), a ciliary protein defective in Leber congenital amaurosis. We show that RPGRIP1L interacts with nephrocystin-4 and that mutations in the gene encoding nephrocystin-4 (NPHP4) that are known to cause SLSN disrupt this interaction. RPGRIP1L is ubiquitously expressed, and its protein product localizes to basal bodies. Therefore, we analyzed RPGRIP1L as a candidate gene for JBTS and identified loss-of-function mutations in three families with typical JBTS, including the characteristic mid-hindbrain malformation. This work identifies RPGRIP1L as a gene responsible for JBTS and establishes a central role for cilia and basal bodies in the pathophysiology of this disorder.     

含余割核奇异积分的求积公式

首先讨论了Hermite三角插值的收敛性问题,然后利用Hermite反三角插值公式建立了反周期函数正常积分的求积公式,最后通过分离奇点的方法建立了含余割核奇异积分的求积公式.     

MetaOJ: A Massive Distributed Online Judge System

Online Judge(OJ) systems are a basic and important component of computer education. Here, we present MetaOJ, an OJ system that can be used for holding massive programming tests online. MetaOJ is designed to create a distributed, fault-tolerant, and easy-to-scale OJ system from an existing ordinary OJ system by adding several interfaces into it and creating multiple instances of it. Our case on modifying the TUOJ system shows that the modification adds no more than 3% lines of code and the performance loss on a single OJ instance is no more than 12%. We also introduce mechanisms to integrate the system with cloud infrastructure to automate the deployment process. MetaOJ provides a solution for those OJ systems that are designed for a specific programming contest and are now facing performance bottlenecks.     

一类奇摄动初值问题解的渐近展开

用边界函数法研究了一类奇摄动初值问题解的渐近展开问题,证明了解的存在惟一性,并给出该解的渐近分析.