Terahertz-field-induced insulator-to-metal transition in vanadium dioxide metamaterial

Electron-electron interactions can render an otherwise conducting material insulating, with the insulator-metal phase transition in correlated-electron materials being the canonical macroscopic manifestation of the competition between charge-carrier itinerancy and localization. The transition can arise from underlying microscopic interactions among the charge, lattice, orbital and spin degrees of freedom, the complexity of which leads to multiple phase-transition pathways. For example, in many transition metal oxides, the insulator-metal transition has been achieved with external stimuli, including temperature, light, electric field, mechanical strain or magnetic field. Vanadium dioxide is particularly intriguing because both the lattice and on-site Coulomb repulsion contribute to the insulator-to-metal transition at 340?K (ref. 8). Thus, although the precise microscopic origin of the phase transition remains elusive, vanadium dioxide serves as a testbed for correlated-electron phase-transition dynamics. Here we report the observation of an insulator-metal transition in vanadium dioxide induced by a terahertz electric field. This is achieved using metamaterial-enhanced picosecond, high-field terahertz pulses to reduce the Coulomb-induced potential barrier for carrier transport. A nonlinear metamaterial response is observed through the phase transition, demonstrating that high-field terahertz pulses provide alternative pathways to induce collective electronic and structural rearrangements. The metamaterial resonators play a dual role, providing sub-wavelength field enhancement that locally drives the nonlinear response, and global sensitivity to the local changes, thereby enabling macroscopic observation of the dynamics. This methodology provides a powerful platform to investigate low-energy dynamics in condensed matter and, further, demonstrates that integration of metamaterials with complex matter is a viable pathway to realize functional nonlinear electromagnetic composites.     

三维各向异性材料数值模型的计算方法

各向异性材料模型的一般计算方法需要编辑偏轴坐标系中的弹性矩阵,其推导过程十分复杂.针对这一问题,提出了一种基于FEM软件中两个坐标系(基本坐标系与辅助坐标系)的新方法.FEM软件自动转换两个坐标系的关系,因此该方法没必要编辑偏轴坐标系中的弹性矩阵,可简化各向异性模型的计算过程.计算结果很好地反映了各向异性材料的方向变化对巷道围岩应力分布的影响.     

Non-invasive measurement and validation of tissue oxygen saturation covered with overlying tissues

In this paper, the biological tissue oxygen saturation （rSO2） is obtained non-invasively and in real time based on near infrared spectroscopy （NIRS） using two emitting wavelengths and two detectors, where the tissue is covered with overlying tissues. Our group developed an NIRS oximeter based on the above principle independently, and validated it using liquid tissue model calibrations and animal experiments. The results indicate that （1） in the normal range of tissue oxygen saturation （40-70%）, the rSO2 measured by NIRS is accurate enough and little influenced by the background absorptions （such as the absorption of water） and overlying tissues （such as fat）; （2） during cerebral hypoxia and recovery of three piglets, there is excellent correlation （p 〈 0.001） between cerebral rSO2 and jugular venous oxygen saturation （SjO2）, meaning that the rSO2 can be indicated by the SjO2 to a large extent; during the death of the three piglets induced by heart beat stopping, cerebral rSO2 decreases continuously to significantly low levels （〈25%） because cerebral blood supply does not exist any more. All the above results are of explicit physiological importance.     

Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors

Flowering plants possess a unique reproductive strategy, involving double fertilization by twin sperm cells. Unlike animal germ lines, the male germ cell lineage in plants only forms after meiosis and involves asymmetric division of haploid microspores, to produce a large, non-germline vegetative cell and a germ cell that undergoes one further division to produce the twin sperm cells. Although this switch in cell cycle control is critical for sperm cell production and delivery, the underlying molecular mechanisms are unknown. Here we identify a novel F-box protein of Arabidopsis thaliana, designated FBL17 (F-box-like 17), that enables this switch by targeting the degradation of cyclin-dependent kinase A;1 inhibitors specifically in male germ cells. We show that FBL17 is transiently expressed in the male germ line after asymmetric division and forms an SKP1-Cullin1-F-box protein (SCF) E3 ubiquitin ligase complex (SCF(FBL17)) that targets the cyclin-dependent kinase inhibitors KRP6 and KRP7 for proteasome-dependent degradation. Accordingly, the loss of FBL17 function leads to the stabilization of KRP6 and inhibition of germ cell cycle progression. Our results identify SCF(FBL17) as an essential male germ cell proliferation complex that promotes twin sperm cell production and double fertilization in flowering plants.     

Mimicking unfolding motion of a beetle hind wing

This paper presents an experimental research aiming to realize an artificial hind wing that can mimic the wing unfolding motion of AIIomyrina dichotoma, an insect in coleopteran order. Based on the understanding of working principles of beetle wing folding/unfolding mechanisms, the hind wing unfolding motion is mimicked by a combination of creative ideas and state-of-art artificial muscle actuator. In this work, we devise two types of artificial wings and the successfully demonstrate that they can be unfolded by actuation of shape memory alloy wires to provide actuation force at the wing base and along the leading edge vein. The folding/unfolding mechanisms may provide an insight for portable nano/micro air vehicles with morphing wings.     

PPARδ inhibits IL-1β-stimulated proliferation and migration of vascular smooth muscle cells via up-regulation of IL-1Ra

Activation of peroxisome proliferator-activated receptor (PPAR) δ by GW501516, a specific PPARδ ligand, significantly inhibited interleukin (IL)-1β-induced proliferation and migration of vascular smooth muscle cells (VSMCs). This effect of GW501516 was dependent on transforming growth factor-β, and was mediated through the up-regulation of IL-1 receptor antagonist. The inhibitory effect of GW501516 on VSMC proliferation was associated with cell cycle arrest at the G1 to S phase transition, which was accompanied by the induction of p21 and p53 along with decreased cyclin-dependent kinase 4 expression. Inhibition of cell migration by GW501516 was associated with the down-regulation of matrix metalloproteinase (MMP)-2 and MMP-9 in IL-1β-treated VSMCs. Inhibition of extracellular signal-regulated kinase significantly reduced the GW501516-mediated inhibition of IL-1β-stimulated VSMC proliferation. These results suggest that PPARδ plays an important role in the pathophysiology of diseases associated with the proliferation and migration of VSMCs.     

Toward Fostering Systems Learning in Organizational Contexts

This article explores the ways in which the process of systems learning can be nurtured in organizational contexts. I posit that in order to mobilize systems learning at the individual, group, and organizational levels, an integrated, holistic approach must be pursued. It is suggested that the challenge of not only teaching the systems thinking concepts but also using their actual applications in practice is more than just an issue of pedagogical improvement. The cultural and material issues integral to the use of systems thinking must be taken into consideration as well. I argue that our efforts to improve our pedagogical practices to foster systems learning in organizational contexts can benefit from the social constructivist perspective, which represents a system of ideas about learning. The qualities of systems pedagogy resided in social constructivism are proposed as a framework to think with in designing the meaningful systems learning activities. This article also discusses how to create the cultural and material environments in which the process of systems learning can be nurtured.