模板支撑体系在建筑工程施工中的应用

文章详细阐述了建筑模板施工技术中的材料选用、扣件式钢管高支撑架设计、验算、施工及构造措施、安装拆除要求等,为保证工程施工的顺利进行了相关探讨.     

基于XML的Web搜索技术研究

文章系统介绍利用XML实现Web信息搜索技术,通过对Web信息的集成、用户兴趣模型的建立和更新、XML数据的查询处理方法,提高网络信息搜索的效率。     

关于电厂在线化学仪表检修维护工作的探讨

文章对牡丹江第二发电厂水汽及制水系统在线化学仪表的运行及检修维护情况进行了全面分析,对仪表的日常管理及维护情况进行了探讨.     

技术哲学视野下中国高铁技术发展探析——论高铁技术与人的“协作与奴役”

中国高铁技术发展迅猛,目前学界对高铁的研究限于技术层面,鉴于高铁运行之后引发的广泛社会争论,本文从技术哲学的视角对高铁技术的来源、运作和影响三个方面的问题,进行哲学探析。认为我国高铁技术应该实现从集成创新转向到原创性创新,以自主创新打破技术的黑箱桎梏;从单一技术到多元技术,以摆脱巨机器奴役;从单纯重视交通经济利益到经济利益与社会效益和环境效益相统一,以保持人、社会、自然三者之间的和谐发展。     

Oxysterols direct immune cell migration via EBI2

Epstein-Barr virus-induced gene 2 (EBI2, also known as GPR183) is a G-protein-coupled receptor that is required for humoral immune responses; polymorphisms in the receptor have been associated with inflammatory autoimmune diseases. The natural ligand for EBI2 has been unknown. Here we describe the identification of 7α,25-dihydroxycholesterol (also called 7α,25-OHC or 5-cholesten-3β,7α,25-triol) as a potent and selective agonist of EBI2. Functional activation of human EBI2 by 7α,25-OHC and closely related oxysterols was verified by monitoring second messenger readouts and saturable, high-affinity radioligand binding. Furthermore, we find that 7α,25-OHC and closely related oxysterols act as chemoattractants for immune cells expressing EBI2 by directing cell migration in vitro and in vivo. A critical enzyme required for the generation of 7α,25-OHC is cholesterol 25-hydroxylase (CH25H). Similar to EBI2 receptor knockout mice, mice deficient in CH25H fail to position activated B cells within the spleen to the outer follicle and mount a reduced plasma cell response after an immune challenge. This demonstrates that CH25H generates EBI2 biological activity in vivo and indicates that the EBI2-oxysterol signalling pathway has an important role in the adaptive immune response.     

短基线定位算法的设计与实现

以用于水池内的短基线定位系统,对船模进行精确定位为研究对象,建立了解算的定位数学模型,仿真和水池实验结果证明了理论的准确性和工程的可行性.并且从理论上分析了产生误差的原因,进行了仿真分析.     

V2O5/ACO催化过氧化氢氧化苯乙烯的研究

以氧化改性活性炭为载体,用微波辐射法制备了系列钒氧化物/活性炭催化剂( V2O5/ACO).采用FT-IR、XRD对催化剂进行了光谱表征.考察了V2O5/ACO在苯乙烯过氧化氢选择氧化中的催化性能.其中,V2O5-30/ACO性能较佳.以丙酮为反应介质,当n(苯乙烯)∶n(H2O2) =1∶2.5,45℃反应5h,苯乙...     

3-正则Halin图的边可区别数

根据3-正则Halin图的Hamilton性,结合其边的相邻关系,通过适当地选取边进行着色后证明了4和6阶以上3-正则Halin图G的边可区别数分别为3和2.     

Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice

Although the question of to whom a male directs his mating attempts is a critical one in social interactions, little is known about the molecular and cellular mechanisms controlling mammalian sexual preference. Here we report that the neurotransmitter 5-hydroxytryptamine (5-HT) is required for male sexual preference. Wild-type male mice preferred females over males, but males lacking central serotonergic neurons lost sexual preference although they were not generally defective in olfaction or in pheromone sensing. A role for 5-HT was demonstrated by the phenotype of mice lacking tryptophan hydroxylase 2 (Tph2), which is required for the first step of 5-HT synthesis in the brain. Thirty-five minutes after the injection of the intermediate 5-hydroxytryptophan (5-HTP), which circumvented Tph2 to restore 5-HT to the wild-type level, adult Tph2 knockout mice also preferred females over males. These results indicate that 5-HT and serotonergic neurons in the adult brain regulate mammalian sexual preference.