黄金果金满堂

说到山东省邹城,很多人都知道那是孔孟之乡.如今,这个以孔孟而闻名的地方又因368元一个的黄金果,再一次引起了人们的关注.     

网络安全防范技术探讨

第四代网络的典型代表是Internet网.2005年全球互联网用户人数达到10.8亿,但由于Internet的开放性和超越组织与国界等特点,以及在安全性上存在的一些隐患,使得计算机网络安全问题越来越凸现.计算机网络安全,是指网络系统的硬件、软件及其系统中的数据受到保护,不受到破坏、更改、泄露,系统能够连续、正常、可靠地运行,网络服务不中断,它指的是计算机网络信息系统中实体安全、运行安全、信息安全的统一.在本文中将对网络安全防范技术作以简单的探讨.     

水钙芒硝的实验研究

水钙芒硝(Hydroglauberite)是1969年发现定名的新矿物,在我国青海、西藏等地盐湖中也多次发现。关于水钙芒硝的实验研究资料甚少,未看到人工合成该矿物的资料,对其化学式尚有不同意见,对其形成的物理化学条件以及它与钙芒硝(Na_2SO_4·CaSO_4)     

锚喷厚度的测定

作者采用超声波作波源,用水泥、沙、石头等原料制成的混凝土灌制在岩石上,作为被测对象,测出混凝土的厚度。实验使用的仪器是SYC-2型声波岩石参数测定仪,该仪器由接收机和发射机组成。发射仪器产生宽度可调的负方波,通过小电缆线加在压电晶体换能器(发射探头)上,产生超声波。超声波通过被测物质传播,被接收换能器(接收探头)转换成电信号,通过电缆线送入接收机放大,显示在示波器上。在厚度测试试验中,发射探头和接收探头均放在混凝土块表面,故反射波的走时方程为:。其中Δ为两探头间的距离,H为混凝土厚度,v为波速,t为反射波到时。其中Δ可直接量出,v也可测出。故只要把反射波的初至到时t读出,就可通过上述方程式解出在实际情况中,反射波初至的拐点是不好辨认的,接收探头接收的波形中,由于有很多震相的迭加而有很多的拐点,但在这     

粗细明暗等高线法的设计

“粗细明暗等高线法”是明暗等高线法的一种表现形式,是在明暗等高线法的基础上设计出来的。明暗等高线法是地貌的一种立体显示法,这种方法既保持了等高线的基本效能,具有明确的数量概念,又具有立体感,所以它是行之有效的方法之一,而且也有许多成功之例。     

Brevetoxicosis: red tides and marine mammal mortalities

Potent marine neurotoxins known as brevetoxins are produced by the 'red tide' dinoflagellate Karenia brevis. They kill large numbers of fish and cause illness in humans who ingest toxic filter-feeding shellfish or inhale toxic aerosols. The toxins are also suspected of having been involved in events in which many manatees and dolphins died, but this has usually not been verified owing to limited confirmation of toxin exposure, unexplained intoxication mechanisms and complicating pathologies. Here we show that fish and seagrass can accumulate high concentrations of brevetoxins and that these have acted as toxin vectors during recent deaths of dolphins and manatees, respectively. Our results challenge claims that the deleterious effects of a brevetoxin on fish (ichthyotoxicity) preclude its accumulation in live fish, and they reveal a new vector mechanism for brevetoxin spread through food webs that poses a threat to upper trophic levels.     

Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway

Enhanced cell migration is one of the underlying mechanisms in cancer invasion and metastasis. Therefore, inhibition of cell migration is considered to be an effective strategy for prevention of cancer metastasis. We found that emodin (3-methyl-1,6,8-trihydroxyanthraquinone), an active component from the rhizome of Rheum palmatum, significantly inhibited epidermal growth factor (EGF)- induced migration in various human cancer cell lines. In the search for the underlying molecular mechanisms, we demonstrated that phosphatidylinositol 3-kinase (PI3K) serves as the molecular target for emodin. In addition, emodin markedly suppressed EGF-induced activation of Cdc42 and Rac1 and the corresponding cytoskeleton changes. Moreover, emodin, but not LY294002, was able to block cell migration in cells transfected with constitutively active (CA)-Cdc42 and CA-Rac1 by interference with the formation of Cdc42/Rac1 and the p21-activated kinase complex. Taken together, data from this study suggest that emodin inhibits human cancer cell migration by suppressing the PI3K-Cdc42/Rac1 signaling pathway.Received 7 February 2005; received after revision 11 March 2005; accepted 18 March 2005