Bregman右投影算子的D-太阳集及其性质

在欧氏空间引进D-太阳集的概念,研究它的性质,并给出了在逼近问题中的应用.     

Analysis of the Structural Reinforcement of the Housing Building Design and Construction Technology

建筑物由于长期使用及风吹日晒,加之地震等自然灾害的侵蚀,会不同程度地出现毁损、裂缝、脱落等问题.文章结合实际施工经验,浅析房屋建筑结构的加固设计及具体施工技术的应用.     

在极低温下照射种子的生物学效应——Ⅳ.对辐射细胞学效应的观察

以微核测定法,对极低温(-196℃)和常温下照射材料的细胞学研究结果表明:极低温有保护效应,能减轻M_1代的生理损伤:辐射种子萌动芽尖间期细胞的微核率与M_2代某些性状突变率具有一定的相关性;极低温单因子处理种子亦可导致染色体畸变。该实验为阐明极低温对种子照射效应的影响提供了微观依据。     

从现代竞走技术发展谈我省竞走裁判队伍的建设

随着竞走技术水平的不断发展和提高,竞走比赛愈加紧张激烈,这就增加了裁判员工作的难度.现代竞走运动对裁判员的能力提出了更高的要求,因为运动员在比赛中能否正常发挥附合规则的技术,这和裁判员的工作有直接关系,所以,建设一支高水平的裁判员队伍,是加速我省竞走运动发展的关键所在。     

几种常见回转曲面短程线的几何分析及其计算机绘制

本文在微分几何理论基础上，通过非线性方程求根与数值积发相结合的方法给出了回转抛物面、回转椭球面、单叶回转双曲面、圆环面等常见回转曲面上短程线的计算方法及其计算机绘制。计算机绘制短程线，在工程实际及数学、物理、力学理论中都是很重要的。     

概率度量空间的致紧性和连通性

本文对概率度量空间上的概率致紧性及概率致紧集的连通性作了数量刻丽,给出了 Menger 空间的点集为概率致紧集的一个充要条件及概率致紧为连通集的充要条件。     

BE—8347—14固定液对水中痕量酚的分离性能的研究

本文用BE—8341—14固定液对松花江水中痕量酚的测定,并对其在气相色谱中的分离性能以模式水样进行了研究。其结果表明,该固定液为实际水样中痕量酚的测定提供了新的参考方法。     

Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons

Many have hypothesized that cell death in Parkinsons disease is via apoptosis and, specifically, by the mitochondrial-mediated apoptotic pathway. We tested this hypothesis using a mouse dopaminergic cell line of mesencephalic origin, MN9D, challenged with the Parkinsonism-causing neurotoxin MPP⁺ (1-methyl-4-phenylpyridinium ion). Apoptosis was the main mode of cell death when the cells were subjected to MPP⁺ treatment under serum-free conditions for 24 h. Caspase-3 and caspase-9, however, were not activated, thus indicating the existence of alternate or compensatory cell death pathway(s) in dopaminergic neuronal cells. Using caspase inhibitors, we demonstrated that these pathways involve caspase-2, –8, –6 and –7. A time-course study indicated that activation of caspase-2 and –8 occurred upstream of caspase-6 and caspase-7. Upon MPP⁺ challenge, the apoptosis-inducing factor was translocated from the mitochondria into the MN9D cytosol and nucleus. These results suggest the existence of alternative apoptotic pathways in dopaminergic neurons.Received 20 September 2004; received after revision 5 November 2004; accepted 22 November 2004     

Dysregulation of the TSC-mTOR pathway in human disease

The mammalian target of rapamycin (mTOR) has a central role in the regulation of cell growth. mTOR receives input from multiple signaling pathways, including growth factors and nutrients, to stimulate protein synthesis by phosphorylating key translation regulators such as ribosomal S6 kinase and eukaryote initiation factor 4E binding protein 1. High levels of dysregulated mTOR activity are associated with several hamartoma syndromes, including tuberous sclerosis complex, the PTEN-related hamartoma syndromes and Peutz-Jeghers syndrome. These disorders are all caused by mutations in tumor-suppressor genes that negatively regulate mTOR. Here we discuss the emerging evidence for a functional relationship between the mTOR signaling pathway and several genetic diseases, and we present evidence supporting a model in which dysregulation of mTOR may be a common molecular basis, not only for hamartoma syndromes, but also for other cellular hypertrophic disorders.     

战术导弹仿真技术的发展与展望

本文论述了仿真技术在战术导弹研制中的重要地位和作用。概述了国外仿真技术在战术导弹上的应用情况以及有关的仿真设备。文中结合我国的实际,提出了当前战术导弹仿真技术面临的几个问题,并就它们的解决途径提出了一些看法和建议。