并行工程环境下过程建模的多视图方法研究

提出了多社图建模方法,且与信息结构方法作了对比,二者都应用于过程管理的信息流建建模,通过对比,分析了多视图建模方法的优点和缺点,说明根据需求而同时采用不同的建模的思想及如何建模,作为实例,给出某典型机械产品开发中设计部分的过程建模的结果。     

关于投资的经济方程稳定性分析

分析了一类经济投资方程的定态解特性,并计算了此类投资方程的定态解稳定性性质,通过计算发现,投资构形的稳定性与人们的投资心理和战略决策辐度有很大的关系,随着参数的变化,投资方程的定态解可能出现稳定焦点、稳定节点、不稳定焦点、不稳定结点以及鞍点等几种情况。     

掺铒硅基纳米发光薄膜的形成过程与性能研究

采用MEVVA离子源强束流离子注入机,将稀土Er离子注入单晶硅、Si和Er离子双注入单晶硅及热氧化硅,Er在硅基薄膜中的掺杂原子分数可达10％,即数密度约10^21cm^-3,注入态样品快速退火后有纳米晶Si形成;77K和室温时用441．6nm光激发有Er^3 较强的1．54μm特征发光发射,探讨了在硅基材料中高浓度Er掺杂薄膜中纳米结构的形成与Er^3 的光致发光性能。     

环状亚砜衍生物α-十二烷-四氢噻吩亚砜的合成

利用四氢噻吩亚砜（TMSO）烷基化合成了环状亚砜衍生物α-十二烷-四氢噻吩亚砜（DTMSO）,讨论了原料的比例、反应温度和反应时间对产率的影响;得到了合成的最佳条件：n(TMSO):n（NaH)：n（C12H25Br）=1:1:1.5;θ1=67℃,t1=1h;θ2=50℃,t2=1h,利用FT-IR,^1H-NMR分析了DTMSO的结构。     

污水生物处理系统中逸出气体的危害与控制

随着人们生活水平和环境意识的提高,污水处理系统逸出气体的问题日益引起人们的关注。笔者从人的意识与环境要求两个方面论述了污水处理设施中逸出气体净化的必要性,并介绍了逸出气体中刺激性成分对人体和构筑物的危害,提出了污水处理中逸出气体控制的主要对象。文中从抑制逸出气体的产生和逸出、气体逸出后所需要的构筑物的密封处理以及密封后气体的净化3个方面对污水处理设施中气体的控制进行了评述,分别简单评价了各种抑制、处理以及净化方法的优缺点,为控制方法的选择提供指导。     

Characterization of PEO-LiClO4-PC Solid Polymer Electrolytes

Plasticized poly (ethylene oxide) based electrolyte membranes of various compositions poly (ethylene oxide) / lithium perchlorate / propylene carbonate were prepared by solution casting. The thermogram, electrical conductivity and vibrational spectra were studied. DSC revealed that the plasticizer propylene carbonate content has influenced on the melting and transition temperature. The infrared spectroscopic study on the effect of PC on the poly (ethylene oxide) / lithium perchlorate / propylene carbonate systems shows that a suitable propylene carbonate content can impede association between lithium ions. Room temperature conductivity changed over 2 order of magnitude, increasing from 6.8 × 10-8 Scm-1 of poly(ethylene oxide) / lithium perchlorate (10/3, w/w) to 8.9 × 10-6 Scm-1 of poly(ethylene oxide) / lithium perchlorate / propylene carbonate (10/3/10, w/w/w). It seems that lithium ions only interact with PEO crystalline phase at the presence of PEO.     

LMI Approach to Observer-based FD Systems Designing

Increasing the robustness to the unknown uncertainty and simultaneously enhancing the sensibility to the faults is one of the important issues considered in the fault detection development. Considering the L2-gain of residual system, this paper deals the observer-based fault detection problem. By using of H∞?control theory, an LMI approach to design fault detection observer is given. A numerical example is used to illustrate the effectiveness of the proposed approach.     

Hybrid particle swarm optimization for multiobjective resource allocation

Resource allocation （RA） is the problem of allocating resources among various artifacts or business units to meet one or more expected goals, such a.s maximizing the profits, minimizing the costs, or achieving the best qualities. A complex multiobjective RA is addressed, and a multiobjective mathematical model is used to find solutions efficiently. Then, all improved particie swarm algorithm （mO_PSO） is proposed combined with a new particle diversity controller policies and dissipation operation. Meanwhile, a modified Pareto methods used in PSO to deal with multiobjectives optimization is presented. The effectiveness of the provided algorithm is validated by its application to some illustrative example dealing with multiobjective RA problems and with the comparative experiment with other algorithm.     

Alcohol dehydrogenase 2 is a major hepatic enzyme for human retinol metabolism

The metabolism of all-trans- and 9-cis-retinol/ retinaldehyde has been investigated with focus on the activities of human, mouse and rat alcohol dehydrogenase 2 (ADH2), an intriguing enzyme with apparently different functions in human and rodents. Kinetic constants were determined with an HPLC method and a structural approach was implemented by in silico substrate dockings. For human ADH2, the determined K_m values ranged from 0.05 to 0.3 μM and k_cat values from 2.3 to 17.6 min⁻¹, while the catalytic efficiency for 9-cis-retinol showed the highest value for any substrate. In contrast, poor activities were detected for the rodent enzymes. A mouse ADH2 mutant (ADH2Pro47His) was studied that resembles the human ADH2 setup. This mutation increased the retinoid activity up to 100-fold. The K_m values of human ADH2 are the lowest among all known human retinol dehydrogenases, which clearly support a role in hepatic retinol oxidation at physiological concentrations. Received 12 October 2006; received after revision 6 December 2006; accepted 8 January 2007     

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the generation of amyloid beta peptide (Abeta) in Alzheimer disease. We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. These variants, which occur in at least two different clusters of intronic sequences within the SORL1 gene (also known as LR11 or SORLA) may regulate tissue-specific expression of SORL1. We also show that SORL1 directs trafficking of APP into recycling pathways and that when SORL1 is underexpressed, APP is sorted into Abeta-generating compartments. These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease.