Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

We have cloned and sequenced the complete complementary DNA of the oestrogen receptor (ER) present in the breast cancer cell line MCF-7. The expression of the ER cDNA in HeLa cells produces a protein that has the same relative molecular mass and binds oestradiol with the same affinity as the MCF-7 ER. There is extensive homology between the ER and the erb-A protein of the oncogenic avian erythroblastosis virus.     

A Generalized Rand-Index Method for Consensus Clustering of Separate Partitions of the Same Data Base

T clusters, based on J distinct, contributory partitions (or, equivalently, J polytomous attributes). We describe a new model/algorithm for implementing this objective. The method's objective function incorporates a modified Rand measure, both in initial cluster selection and in subsequent refinement of the starting partition. The method is applied to both synthetic and real data. The performance of the proposed model is compared to latent class analysis of the same data set.     

Use of radio transmitter implants in wild canids

Twelve adult and five juvenile coyotes and 20 adult kit foxes were implanted with radio transmitters using relatively simple surgical procedures. Four foxes were successfully implanted in the field. None of the animals implanted exhibited noticeable behavioral effects, and no deaths were confirmed to result from implantation. Implants were attached to the peritoneum in adult coyotes and kit foxes and were left free - floating within the abdominal cavity of the coyote pups. Both procedures produced satisfactory results. Radio signals transmitted from implants had less range than those from traditional neck collar transmitters. Implants offered benefits unavailable with traditional collar transmitters: no external packaging to influence behavior, ability to radio monitor small or juvenile animals, and ability to acquire various physiological data on free - ranging individuals.