论《间谍》的双重解读

Joseph Conrad是英国杰出的小说家,他的海洋小说和丛林小说颇为人关注,但人们对他的社会小说却感到陌生。《间谍》是Conrad重要的政治小说,被认为是作者艺术创作最完美成熟的作品之一,然而学者们对其故事内容和主题评论存在不同的理解:一种观点坚持认为无政府主义是小说的中心,另一种则相信道德关怀才是小说的主旨。笔者赞同后者的观点,认为小说的主题是道德沦丧。本文就此问题对《间谍》进行解读,剖析作者巧妙利用无政府主义和家庭生活之间的关系,展示出人性和道德的社会伦理问题。     

J-TEXT托卡马克上的可见光CCD成像系统

在中型聚变实验装置J-TEXT托卡马克上成功地研制了一套可见光CCD(12harge Coupled Device)成像系统.该系统可沿切向实时观察整个等离子体横截面的可见光辐射图形.该系统的核心器件CCD相机分辨率为659×494,最高帧率110f/s,可按选择捕捉彩色或黑白图片.详细地描述了该成像系统的组成、CCD相机的控制流程以及实际应用的结果.该系统能直观地展现等离子体放电过程,是J-TEXT装置放电运行中必备的重要诊断手段.     

Radiation hybrid map of the mouse genome.

Radiation hybrid (RH) maps are a useful tool for genome analysis, providing a direct method for localizing genes and anchoring physical maps and genomic sequence along chromosomes. The construction of a comprehensive RH map for the human genome has resulted in gene maps reflecting the location of more than 30,000 human genes. Here we report the first comprehensive RH map of the mouse genome. The map contains 2,486 loci screened against an RH panel of 93 cell lines. Most loci (93%) are simple sequence length polymorphisms (SSLPs) taken from the mouse genetic map, thereby providing direct integration between these two key maps. We performed RH mapping by a new and efficient approach in which we replaced traditional gel- or hybridization-based assays by a homogeneous 5'-nuclease assays involving a single common probe for all genetic markers. The map provides essentially complete connectivity and coverage across the genome, and good resolution for ordering loci, with 1 centiRay (cR) corresponding to an average of approximately 100 kb. The RH map, together with an accompanying World-Wide Web server, makes it possible for any investigator to rapidly localize sequences in the mouse genome. Together with the previously constructed genetic map and a YAC-based physical map reported in a companion paper, the fundamental maps required for mouse genomics are now available.     

ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS or SACS) is an early onset neurodegenerative disease with high prevalence (carrier frequency 1/22) in the Charlevoix-Saguenay-Lac-Saint-Jean (CSLSJ) region of Quebec. We previously mapped the gene responsible for ARSACS to chromosome 13q11 and identified two ancestral haplotypes. Here we report the cloning of this gene, SACS, which encodes the protein sacsin. The ORF of SACS is 11,487 bp and is encoded by a single gigantic exon spanning 12,794 bp. This exon is the largest to be identified in any vertebrate organism. The ORF is conserved in human and mouse. The putative protein contains three large segments with sequence similarity to each other and to the predicted protein of an Arabidopsis thaliana ORF. The presence of heat-shock domains suggests a function for sacsin in chaperone-mediated protein folding. SACS is expressed in a variety of tissues, including the central nervous system. We identified two SACSmutations in ARSACS families that lead to protein truncation, consistent with haplotype analysis.     

L_n（S_1×S_2×…×S_k）设计的数学模型及其统计分析

给出Ｌｎ（Ｓ１×Ｓ２×…×Ｓｋ）正交设计的数学模型，并在线性模型一般理论的基础上，对正交设计模型中的估计问题进行了统计分析．     

基于α-Stable自相似随机过程的通信网业务量建模

针对现代通信网业务量在幅度和时间尺度上的突发特性，提出了一种综合稳定分布和高斯自相似分布的模型，即基于α-Stable自相似过程的模型来同时反映业务量的两种突发特性，并通过仿真证明了它非常适合于现代通信网的业务量，该模型可以根据不同的性能需要来产生相应的模拟业务量，从而对网络业务量性能相关的研究有一定的实用价值。     

Study of Treating HAPE with HBO in Situ at the Altitude of 4636 m

Study Objective ： To evaluate the treatment effect of HAPE with HBO in situ at an extreme altitude of 4636 m. To investigate the relationship between pulmonary hypertension （PH） and HAPE. To emphasize the importance of the treatment in situ. Methods： The 32 patients from the plateau of 4636 - 5130 m （the barometric pressure： 57.41 - 53.28 kPa/431.6 - 400.6 mmHg（1 mmHg = 133.3224 Pa）, the partial pressure of oxygen： 12.0 - 11.6 kPa/90.0 - 87.0 mmHg） were treated in situ of 4636 m altitude with HBO. Before and after the treatment, the clinical symptoms / signs, radiographic evidence, SaO2, and MPAP were compared. Results： The clinical symptoms/signs, and all the targets of the patients were improved dramatically （p 〈 0.001）. Conclusions： Treating HAPE with HBO is the most effective method among various therapies in situ at an extreme altitude. The pulmonary -artery pressure was significantly decreased. All eases showed improved immediately. Among the subjects, 11 eases （34.3 %） were cured at once. The therapy made it possible for patients to get further treatment at a lower altitude area with prospective good results. We suggested that treating HAPE with HBO should be the first choice in situ. There must be PH in the patients of HAPE, but the reverse is not the true. The PH is a mechanism of normal compensation of the body exposing in the hypoxie environment. It is very necessary for us to explore the threshold of PH when a HAPE happens.     

Biosynthesis of selenosubtilisin: A novel way to target selenium into the active site of subtilisin

Glutathione peroxidase （GPx, EC1.11.1.9）, an important anti-oxidative selenoenzyme, can catalyze the reduction of harmful hydroperoxides with concomitant glutathione, thereby protecting cells and other biological issues against oxidative damage. It captures considerable interest in redesign of its function for either the mechanism study or the pharmacological development as an antioxidant. In order to develop a general strategy for specifically targeting and operating selenium in active sites of enzymes, the catalytically essential residue selenocysteine （Sec） was first successfully bioincorporated into the catalytic center of subtilisin by using an auxotrophic expression system. The studies of the catalytic activity and the steady-state kinetics demonstrated that selenosubtilisin is an excellent GPx-like biocatalyst. In comparison with the chemically modified method, biosynthesis exhibits obvious advantages： Sec could be site-directly incorporated into active sites of enzymes to overcome the non-specificity generated by chemical modification. This study provides an important strategy for specifically targeting and operating selenium in the active site of an enzyme.     

抗松针褐斑病湿地松组培再生植株生长性状观察

对移栽至南京林业大学南大山苗圃的湿地松组培再生植株进行了苗高、地径、干形的比较。结果表明,各家系及无性系的生长状态存在差异。组培苗与实生苗间苗高差异较大,组培苗在早期生长速度不及实生苗,且抗病的家系不及普通的家系,抗病的8#和32#家系苗高差异不显著;实生苗、组培苗斜生现象严重;继代次数对组培苗的苗高、地径生长影响不大;组培苗年龄越大,苗高生长势越好,地径差异小;8#家系组培苗各无性系间苗高差异显著,地径差异不显著。     

Controllability and Observability of Stochastic Singular Systems in Banach Spaces

Journal of Systems Science and Complexity - Exact (approximate) controllability and exact (approximate) observability of stochastic singular systems in Banach spaces are discussed. Firstly, the...