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771.
将求解k(k≥2)阶线性递归方程组问题转化为求矩阵序列部分积问题,在SIMD共享存储模型上提出了求解k阶线性递归方程组的一种新的有效并行算法.研究表明,本算法的加速和效率比现有算法均有较大的改善. 相似文献
772.
证明了当n>3时,使过半数投票表决的结果具有传递性的个人偏好序的最大数目大于2 ̄(n-),从而否定了Craven猜想。文中给出了最大偏好序的递推公式以及确定相应约束集的三条规则。 相似文献
773.
应用扩展的Monod模型关联了醋酸菌IAM1802和M23的比生长速率,IAM1802的比生长速率关联式为μ=0.487(1-CP/23.8)^0.248CA/CM+CA;M23的关联式为μ=0.568(1-CP/61.0)^0.306CA/CM+CA除临界生长抑制剂浓度附近外,模型良好地表达了两种醋力的比生长速率。 相似文献
774.
本文阐述了水轮机变结构变参数调速控制的基本问题,提出了相应的控制策略,并论证该控制策略的稳定性、最优性。仿真结果表明本文提出的策略控制效果优良。 相似文献
775.
本文研究了控制量变化率受限时的MRAS控制。在文献[1~3]的启发下,本文提出了控制量变化率受限时的MRAS鲁棒变结构控制问题;给出了控制器结构、控制律、自适应律,分析了系统的稳定性和渐近收敛性。 相似文献
776.
本文提出了智能化自完善控制策略,通过采用“知识库”存贮最佳的知识与经验,根据受控对象当前运行条件及状态,运用相应的分析逻辑及推理功能,实时地调整控制器结构及参数,以实现逐步改善控制系统性能的目的.文中将所论述的控制策略用于水轮机调速器开发研究. 相似文献
777.
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II 总被引:122,自引:0,他引:122
Ribosomal protein S6 is a component of the eukaryotic 40S ribosomal subunit that becomes phosphorylated on multiple serine residues in response to a variety of mitogens, including insulin, growth factors, and transforming proteins of many oncogenic viruses. Recently, an activated S6 kinase (S6 K II) has been purified to homogeneity from Xenopus eggs, and characterized immunologically and at the molecular level. Purified S6 K II can be deactivated in vitro by incubation with either protein phosphatase 1 or protein phosphatase 2A. Reactivation and phosphorylation of S6 K II occurs in vitro with an insulin-stimulated microtubule-associated protein-2 (MAP-2) protein kinase which is itself a phosphoprotein that can be deactivated by protein phosphatase 2A. These studies suggest that a step in insulin signalling involves sequential activation by phosphorylation of at least two serine/threonine protein kinases. 相似文献
778.
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity 总被引:98,自引:0,他引:98
Alzheimer's disease is characterized by cerebral deposits of amyloid beta-protein (AP) as senile plaque core and vascular amyloid, and a complementary DNA encoding a precursor of this protein (APP) has been cloned from human brain. From a cDNA library of a human glioblastoma cell line, we have isolated a cDNA identical to that previously reported, together with a new cDNA which contains a 225-nucleotide insert. The sequence of the 56 amino acids at the N-terminal of the protein deduced from this insert is highly homologous to the basic trypsin inhibitor family, and the lysate from COS-1 cells transfected with the longer APP cDNA showed an increased inhibition of trypsin activity. Partial sequencing of the genomic DNA encoding APP showed that the 225 nucleotides are located in two exons. At least three messenger RNA species, apparently transcribed from a single APP gene by alternative splicing, were found in human brain. We suggest that protease inhibition by the longer APP(s) could be related to aberrant APP catabolism. 相似文献
779.
780.
An H+-ATPase in opposite plasma membrane domains in kidney epithelial cell subpopulations 总被引:20,自引:0,他引:20
Vectorial solute transport by epithelia requires the polarized insertion of transport proteins into apical or basolateral plasmalemmal domains. In the specialized intercalated cells of the kidney collecting duct, the selective placement of an apical plasma membrane proton-pumping ATPase (H+-ATPase) and of a basolateral membrane anion-exchange protein results in transepithelial proton secretion. It is currently believed that amino-acid sequences of membrane proteins contain critical signalling regions involved in sorting these proteins to specific membrane domains. Recently, it was proposed that intercalated cells can reverse their direction of proton secretion under different acid-base conditions by redirecting proton pumps from apical to basolateral membranes, and anion exchangers from basolateral to apical membranes. But others have found that antibodies raised against the red cell anion-exchange protein (Band 3) only labelled intercalated cells at the basolateral plasma membrane, providing evidence against the model of polarity reversal. In this report, we have examined directly the distribution of proton pumps in kidney intercalated cells using specific polyclonal antibodies against subunits of a bovine kidney medullary H+-ATPase. We find that some cortical collecting duct intercalated cells have apical plasma membrane proton pumps, whereas others have basolateral pumps. This is the first direct demonstration of neighbouring epithelial cells maintaining opposite polarities of a transport protein. Thus, either subtle structural differences exist between proton pumps located at opposite poles of the cell, or factors other than protein sequence determine the polarity of H+-ATPase insertion. 相似文献