论桥梁抗震模型建立分析的目的

文章论述了桥梁抗震评估的建立模型和分析手段,其目的是用结构位移、构件受力及变形对桥梁地震反应进行定量化分析.     

吉林铁通波分复用设备的应用

文章介绍了一种新的传输技术——密集波分复用技术。主要介绍了吉林铁通ZXWM M900干线DWDM系统及ZXMP M800城域DWDM系统。WDM技术目前已形成覆盖全省的骨干网络。铁通公司以大容量光网络设备ZXWM M900在北京、天津、辽宁、黑龙江及吉林省成功建成环型组网。     

公路建设项目合同管理现状及对策措施

根据目前公路建设合同管理的现状,作者在分析公路建设合同管理工作中的不足及成因的基础上,提出了加强公路建设合同管理的对策和措施。     

基于累积运动能量图像的人体动作识别

指出了动作识别中的最大困难是难以提取有效的特征来准确描述人体的动作,动作模板是众多方法中的一种简单有效的方法,用来描述动作特征的经典动作模板是运动历史图像.由于受噪声的干扰,用运动历史图像描述复杂环境下的人体动作并不十分理想.为了得到比运动历史图像更加有效的动作模板,提出了将视频序列中的运动能量信息用一张图描述出来,称之为累积运动能量图像,提取其直方图特征来表征人体动作.经You Tube数据集上的实验表明:该累积运动能量图像的识别率比同类方法高.     

A second generation human haplotype map of over 3.1 million SNPs

We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common SNP variation in the populations surveyed. The map is estimated to capture untyped common variation with an average maximum r2 of between 0.9 and 0.96 depending on population. We demonstrate that the current generation of commercial genome-wide genotyping products captures common Phase II SNPs with an average maximum r2 of up to 0.8 in African and up to 0.95 in non-African populations, and that potential gains in power in association studies can be obtained through imputation. These data also reveal novel aspects of the structure of linkage disequilibrium. We show that 10-30% of pairs of individuals within a population share at least one region of extended genetic identity arising from recent ancestry and that up to 1% of all common variants are untaggable, primarily because they lie within recombination hotspots. We show that recombination rates vary systematically around genes and between genes of different function. Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations.     

Genome-wide detection and characterization of positive selection in human populations

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.     

基于DiffServ的UMTS端到端QoS保证机制研究

3G多媒体业务的发展给UMTS的QoS保证机制提出更高的要求.从QoS需求出发,描述了无线接入网的网络结构以及3G核心网的承载业务类型,分析了网络组件、业务类型与协议栈之间的对应关系,讨论了UMTS QoS管理机制在各组件中的功能实现,引入因特网的区分服务模型在核心网中构建基于DiffServ的网络模型为不同业务提供QoS保证,最后指出UMTS端到端QoS机制有待发展的研究方向.     

实时定量PCR检测B细胞恶性肿瘤中BCL11A基因的表达水平

目的:建立B细胞淋巴瘤/白血病BCL11A基因的定量检测方法,并分析其在B细胞恶性肿瘤中的表达水平。方法:利用实时定量RT-PCR分析B细胞淋巴瘤(18例)、B细胞性慢性淋巴细胞白血病(B-CLL,8例)、T细胞性急性淋巴细胞白血病(T-ALL,8例)和正常对照(15例)外周血单个核细胞(PBMC)中BCL11A基因的表达水平,以甘油醛-3-磷酸脱氢酶(GAPDH)基因作为内对照。结果:B-CLL组和B细胞淋巴瘤组患者PBMC中BCL11A表达水平均明显高于正常对照(P=0.000)和T-ALL组(P=0.000);T-ALL组和正常对照组BCL11A表达水平无显著差别(P=0.084);B-CLL组和B细胞淋巴瘤组BCL11A表达水平无显著差别(P=0.776)。在B细胞淋巴瘤不同的病例中,BCL11A表达水平有较大差异,其中最小值为0.04,最大值为9.70,中位值为1.00。结论:成功建立BCL11A基因的定量检测方法。     

高速铁路运行引发的低频振动的隔振分析

针对传统隔振方法对低频振动无法取得较好效果的问题,分析了波阻块( WIB)和蜂窝形波阻块( HWIB)对高速铁路引发的低频振动的隔振效果.首先建立了列车-路基的数值计算模型,将列车荷载简化为沿路基向前的移动荷载列,并采用基于拉格朗日算法的有限差分软件计算了埋设WIB和HWIB前后场地土的振动情况,最后与空沟的隔振效果进...     

全分集协作系统C-HARQ方案的设计及性能

为了进一步提高全分集协作(FDC)系统的可靠性和有效性,提出了两种协作混合自动请求重传(C-HARQ)方案.定长帧协作混合重传(FFC-HARQ)方案在不改变全分集协作系统原有帧结构的基础上,使用一定的检错重传策略提高系统吞吐量;变长帧协作混合重传(VFC-HARQ)方案则改变原有帧结构,进一步提高系统吞吐量.利用马尔...