全文获取类型
收费全文 | 29170篇 |
免费 | 278篇 |
国内免费 | 478篇 |
专业分类
系统科学 | 457篇 |
丛书文集 | 326篇 |
教育与普及 | 394篇 |
理论与方法论 | 122篇 |
现状及发展 | 9200篇 |
研究方法 | 951篇 |
综合类 | 18087篇 |
自然研究 | 389篇 |
出版年
2014年 | 319篇 |
2013年 | 344篇 |
2012年 | 628篇 |
2011年 | 1056篇 |
2010年 | 422篇 |
2009年 | 483篇 |
2008年 | 744篇 |
2007年 | 749篇 |
2006年 | 693篇 |
2005年 | 683篇 |
2004年 | 651篇 |
2003年 | 554篇 |
2002年 | 591篇 |
2001年 | 851篇 |
2000年 | 897篇 |
1999年 | 826篇 |
1998年 | 438篇 |
1997年 | 441篇 |
1996年 | 442篇 |
1995年 | 392篇 |
1994年 | 395篇 |
1993年 | 329篇 |
1992年 | 626篇 |
1991年 | 487篇 |
1990年 | 527篇 |
1989年 | 495篇 |
1988年 | 454篇 |
1987年 | 454篇 |
1986年 | 392篇 |
1985年 | 486篇 |
1984年 | 376篇 |
1983年 | 292篇 |
1981年 | 279篇 |
1980年 | 282篇 |
1979年 | 683篇 |
1978年 | 570篇 |
1977年 | 466篇 |
1976年 | 479篇 |
1975年 | 473篇 |
1974年 | 544篇 |
1973年 | 473篇 |
1972年 | 456篇 |
1971年 | 608篇 |
1970年 | 800篇 |
1969年 | 542篇 |
1968年 | 580篇 |
1967年 | 585篇 |
1966年 | 575篇 |
1965年 | 385篇 |
1958年 | 354篇 |
排序方式: 共有10000条查询结果,搜索用时 421 毫秒
781.
782.
交互电视是利用HFC网络提供包括电视节目在内的交互式数字媒体服务.对交互电视系统的架构和设计方式进行了介绍,并详细分析了机顶盒的点播流程. 相似文献
783.
运用矩阵的ΣKL分解及相关矩阵的特征,研究了广义投影算子(A~2=A~*)和超广义投影算子(A~2=A~■)的性质,得到了一些新的刻画,这些结果推广了Baksalary的相关结果。 相似文献
784.
785.
Gene polymorphism in Netherton and common atopic disease. 总被引:13,自引:0,他引:13
A J Walley S Chavanas M F Moffatt R M Esnouf B Ubhi R Lawrence K Wong G R Abecasis E Y Jones J I Harper A Hovnanian W O Cookson 《Nature genetics》2001,29(2):175-178
Atopic dermatitis (AD) and asthma are characterized by IgE-mediated atopic (allergic) responses to common proteins (allergens), many of which are proteinases. Loci influencing atopy have been localized to a number of chromosomal regions, including the chromosome 5q31 cytokine cluster. Netherton disease is a rare recessive skin disorder in which atopy is a universal accompaniment. The gene underlying Netherton disease (SPINK5) encodes a 15-domain serine proteinase inhibitor (LEKTI) which is expressed in epithelial and mucosal surfaces and in the thymus. We have identified six coding polymorphisms in SPINK5 (Table 1) and found that a Glu420-->Lys variant shows significant association with atopy and AD in two independent panels of families. Our results implicate a previously unrecognized pathway for the development of common allergic illnesses. 相似文献
786.
Frank W. Pfrieger 《Cellular and molecular life sciences : CMLS》2009,66(13):2037-2047
Brain function relies on communication among neurons via highly specialized contacts, the synapses, and synaptic dysfunction lies at the heart of age-, disease-, and injury-induced defects of the nervous system. For these reasons, the formation—and repair—of synaptic connections is a major focus of neuroscience research. In this review, I summarize recent evidence that synapse development is not a cell-autonomous process and that its distinct phases depend on assistance from the so-called glial cells. The results supporting this view concern synapses in the central nervous system as well as neuromuscular junctions and originate from experimental models ranging from cell cultures to living flies, worms, and mice. Peeking at the future, I will highlight recent technical advances that are likely to revolutionize our views on synapse–glia interactions in the developing, adult and diseased brain. 相似文献
787.
群集技术在门户系统中的应用 总被引:1,自引:0,他引:1
对微软服务器群集技术进行了较为深入的探讨,特别对MSCS技术,在兰州石化公司门户数据库服务器中的应用进行了详细介绍和分析,包括工作机理、实施步骤和应用效果。 相似文献
788.
Equilibrating metal-oxide cluster ensembles for oxidation reactions using oxygen in water. 总被引:2,自引:0,他引:2
I A Weinstock E M Barbuzzi M W Wemple J J Cowan R S Reiner D M Sonnen R A Heintz J S Bond C L Hill 《Nature》2001,414(6860):191-195
Although many enzymes can readily and selectively use oxygen in water-the most familiar and attractive of all oxidants and solvents, respectively-the design of synthetic catalysts for selective water-based oxidation processes utilizing molecular oxygen remains a daunting task. Particularly problematic is the fact that oxidation of substrates by O2 involves radical chemistry, which is intrinsically non-selective and difficult to control. In addition, metallo-organic catalysts are inherently susceptible to degradation by oxygen-based radicals, while their transition-metal-ion active sites often react with water to give insoluble, and thus inactive, oxides or hydroxides. Furthermore, pH control is often required to avoid acid or base degradation of organic substrates or products. Unlike metallo-organic catalysts, polyoxometalate anions are oxidatively stable and are reversible oxidants for use with O2 (refs 8,9,10). Here we show how thermodynamically controlled self-assembly of an equilibrated ensemble of polyoxometalates, with the heteropolytungstate anion [AIVVW11O40]6- as its main component, imparts both stability in water and internal pH-management. Designed to operate at near-neutral pH, this system facilitates a two-step O2-based process for the selective delignification of wood (lignocellulose) fibres. By directly monitoring the central Al atom, we show that equilibration reactions typical of polyoxometalate anions keep the pH of the system near 7 during both process steps. 相似文献
789.
Phot1 and phot2 mediate blue light regulation of stomatal opening. 总被引:36,自引:0,他引:36
The stomatal pores of higher plants allow for gaseous exchange into and out of leaves. Situated in the epidermis, they are surrounded by a pair of guard cells which control their opening in response to many environmental stimuli, including blue light. Opening of the pores is mediated by K(+) accumulation in guard cells through a K(+) channel and driven by an inside-negative electrical potential. Blue light causes phosphorylation and activation of the plasma membrane H(+)-ATPase that creates this potential. Thus far, no blue light receptor mediating stomatal opening has been identified, although the carotenoid, zeaxanthin, has been proposed. Arabidopsis mutants deficient in specific blue-light-mediated responses have identified four blue light receptors, cryptochrome 1 (cry1), cryptochrome 2 (cry2), phot1 and phot2. Here we show that in a double mutant of phot1 and phot2 stomata do not respond to blue light although single mutants are phenotypically normal. These results demonstrate that phot1 and phot2 act redundantly as blue light receptors mediating stomatal opening. 相似文献
790.
Gao Qiusheng 《科学之友》2012,(15)
企业的全面预算管理对现代企业成熟与发展起到了重大推动作用,是企业内部管理控制的一种有效方法,是值得我国企业学习和借鉴的管理手段.它有助于现代企业制度的建立,有助于企业合理配置资源,有助于现代财务管理方式的适时预算管理.但是,我国企业在实施全面预算管理中还存在一些问题,其观念落后,内容欠缺,只重编制,使得全面预算整体效果不佳.所以,企业要树立科学的全面预算管理理念,建立健全全面预算管理体系,重视控制和考评环节,使这种科学的管理制度能充分发挥其效能. 相似文献