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211.
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To eliminate the load weight limit of carrier rockets and reduce the burden on support struc-tures,in-orbit assembly is a key technology to make design of scattering a large diameter telescope into submirror modules, which requires smooth operation of assembly robots, and flexible force con-trol technology is necessary.A ground demonstration system is presented for in-orbit assembly focu-sing on flexible force control.A six-dimensional force/torque sensor and its data acquisition system are used to compensate for gravity.For translation and rotation, an algorithm for flexible control is proposed.A ground transportation demonstration verifies accuracy and smoothness of flexible force control, and the transportation and assembly task is completed automatically.The proposed system is suitable for the development of in-orbit assembly robots. 相似文献
213.
Mengyang Liu Yuanli Chen Xiaoxiao Yang Ling Zhang Tao Zhao Buchang Zhao Lifu Jia Yan Zhu Xiumei Gao Boli Zhang Xiaoju Li Rong Xiang Jihong Han Yajun Duan 《科学通报(英文版)》2014,59(13):1366-1373
Clinical observations indicate that DanHong Injection (DHI) can increase blood flow and reduce various syndromes in patients with cardiovascular disease. How- ever, it still needs to define the function of DHI and the involved mechanisms in details, such as the protective effect on the development of primary abdominal aortic aneurysms (AAAs). In this study, we determined whether DHI is able to inhibit AAA in apoE knockout (apoE-/-) mice. Thirty apoE-/- male mice on high-fat diet (0.5 % cholesterol, 21% fat) were randomly divided into two groups and received i.p. injection of saline (100 μL/day) and DHI (100 μL/day), respectively, for 16 weeks. At the end of experiment, we determined the development of atherosclerosis in en face aorta and aneurysms,pathological morphology of arterial wall, and serum lipid levels. We also determined the expression of monocyte chemoattractant protein-1 (MCP-1), MMP-2, and MMP-9 mRNA in aortic wall using real-time RT-PCR. Our results indicated that high-fat diet induced the development of AAAs in apoE-/- mice, but the induction was totally blocked by DHI (P 〈 0.01). The result of staining of abdominal aortic cross sections showed that DHI main- tained the collagen content in arterial wall, thereby pre- venting the animals from the development of AAA. Although DHI had little effect on serum total- and LDL- cholesterol levels, it reduced the expression of MCP-1, MMP-2, and MMP-9 mRNA in aortic wall (P 〈 0.01). Taken together, our study suggests that DHI can inhibit the high-fat diet-induced AAA formation. The inhibitory effects may be related to the maintenance of the collagen content and inhibition of expression of AAA-related genes. Our study may suggest a new application of DHI in clinics. 相似文献
214.
Molla R. Islam Yongfeng Gao Xue Li Qiang Matthew Zhang Menglian Wei Michael J. Serpe 《科学通报(英文版)》2014,59(32):4237-4255
Stimuli-responsive polymers have the extraor- dinary ability to change their physical and/or chemical state after they "detect" a change in their environment; their response depends dramatically on their chemical compo- sition. This property has been used for a plethora of applications; this review highlights their utility for human health. Specifically, this review will highlight efforts in the areas of sensing and biosensing, antimicrobial/antifouling coatings, tissue engineering and regenerative medicine, and drug delivery. Specific examples are given in each of these areas, with some focus on our work engineering poly(N- isopropylacrylamide)-based microgels and other respon- sive systems. 相似文献
215.
高霞 《曲靖师范学院学报》2016,(4):65-70
清莱府以其优越的地理位置和历史文化积淀,促使汉语教学成为泰国发展较快的地区之一。采用问卷调查法和访谈法,以泰国清莱府13所中小学汉语实习教师为调查对象,分别从师资、教材、课时等情况调查汉语教学基本现状,分析该地区中小学汉语教学中存在的诸多问题,并提出相应建议和解决对策。 相似文献
216.
碘化N-正丁基氟哌啶醇(N-n-butyl haloperidol iodide,F2)为本研究室改造合成的新化合物。前期研究发现F2作为L-型钙通道拮抗剂,能剂量依赖地拮抗缺血再灌注所导致的大鼠心脏损伤。研究F2对缺氧复氧(hypoxia/reoxygenation,H/R)大鼠心肌细胞钠钙交换体电流的作用并探讨其保护机制。采用Langendorff灌流系统灌流SD大鼠心脏,标准酶解法消化分离得到单个心室肌细胞。正常台式液灌流5min,立即灌流充90%N2-10%CO2的缺氧液,建立体外心肌细胞H/R模型,采用全细胞膜片钳技术记录对照、模型以及不同浓度F2(0.1、1、10μmol/L)对心肌细胞钠钙交换体电流,观察H/R状态F2对心肌细胞钠钙交换体电流的影响。结果显示:缺氧抑制钠钙交换体电流主要是抑制外向电流;H/R引起钠钙交换体电流增大,尤其是外向电流的增大。F2呈浓度依赖地抑制钠钙交换体电流,钠钙交换体电流I-V曲线上移。以上表明:F2能抑制钠钙交换体电流,尤其是外向电流,防止H/R时心肌细胞的钙超载,保护心肌细胞。 相似文献
217.
随着自动化集装箱码头成为当今码头的发展趋势,AGV(automated guided vehicle) 作为自动化码头中使用最为广泛的水平运输工具,合理制定其充电策略至关重要。针对当前自动化集装箱码头中AGV充电策略的不足,提出一种以离线充电为主在线充电为辅的充电策略,并且针对在线充电站点位置选择问题提出一种利用热区图选择有效在线充电站点的快捷方法。在使用该种充电策略情况下,通过大量仿真实验得出在码头工作任务量不变的前提下可减少AGV数量配置的结果,说明自动化集装箱码头水平搬运效率得到提高,证明该充电策略具有有效性。 相似文献
218.
This paper proposes five new simple moment estimators of the effective spread based on the covariance estimator of Roll(1984) and the High-Low estimator recently developed by Corwin and Schultz(2012). And then the authors theoretically investigate the statistical properties of six simple High-Low spread estimators including Corwin and Schultz's estimator. The biases and mean squared errors(MSE) of these six estimators have been derived and compared with each other asymptotically,which, together with the subsequent simulation study, reveal explicitly the superior performance of newly developed High-Low estimators over Corwin and Schultz's estimator in both ideal and nonideal conditions. Moreover, this paper also develops GMM estimators constructed by three or more moment conditions and compares with the six simple High-Low estimators. Finally, several example applications on the U.S. and Chinese financial markets are conducted to demonstrate the superior performance of the new High-Low estimators. The results provide alternative choices for identifying the liquidity proxies that well capture different structure of markets. 相似文献
219.
220.
This paper is devoted to a study of the null controllability problems for one-dimensional linear degenerate wave equations through a boundary controller. First, the well-posedness of linear degenerate wave equations is discussed. Then the null controllability of some degenerate wave equations is established, when a control acts on the non-degenerate boundary. Different from the known controllability results in the case that a control acts on the degenerate boundary, any initial value in state space is controllable in this case. Also, an explicit expression for the controllability time is given. Furthermore, a counterexample on the controllability is given for some other degenerate wave equations. 相似文献