新型桥梁施工挂篮XG—A的研究与应用

根据修建海沙大桥工程的需要,专门研制了一种超轻型滑动斜拉式的新型桥梁施工挂篮XG—A.该挂篮自重轻、效率高是目前国内较先进的桥梁施工设备.     

多参数Wiener过程平方函数积分的重对数律

设Ｗ（ｔ）是ｄ维参数Ｗｉｅｎｅｒ过程，我们在此文中证明     

实现“（dE／dt）~（－1）－E”倒数示波图的模拟电路参数选择和单板机装置

对实现“（ｄＥ／ｄｔ）－１－Ｅ”倒数示波图的实验装置进行了进一步深入研究：改进了以往的模拟电路，考察了电参数的影响；研制了一台单板机装置．     

日式经营管理在邃变

８０年代引人注目的日式经营管理，９０年代来其许多本质性特征却发生了意味深长的变化。注视并研究这些变化意义甚大。本文重在概括日式经营管理现正经历的变化。     

水稻花粉悬浮培养及其在育种上的应用

评估了２０个水稻品种离体花粉悬浮培养产生愈伤组织和再分化植株的能力，并进行了花粉悬浮培养试验，结果表明；品种之间反应差异很大。来源于日本的“黎明”（粳稻）最敏感。“黎明”植株再分化的频率达８４．１％。在愈伤组织的形成和植株再分化过程中，除其它一些因子外，基因型的差异有一定制约作用。通过水稻花粉悬浮培养诱导出的新品系“Ｎ１０”，其特征有：早熟，穗大，株高（９０～１００ｃｍ），产量高和抗稻瘟病等。     

师资预测一类纵横统计推进模型

提出了一个新的人才预测模型,其主要优点是可对残缺原始数据进行加工,且可修正预测值的随机误差影响,预测精度较高.本文还给出了用该模型对某校师资进行预测的实例,得到满意结果.     

Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.

The inherited osteolyses or 'vanishing bone' syndromes are a group of rare disorders of unknown etiology characterized by destruction and resorption of affected bones. The multicentric osteolyses are notable for interphalangeal joint erosions that mimic severe juvenile rheumatoid arthritis (OMIMs 166300, 259600, 259610 and 277950). We recently described an autosomal recessive form of multicentric osteolysis with carpal and tarsal resorption, crippling arthritic changes, marked osteoporosis, palmar and plantar subcutaneous nodules and distinctive facies in a number of consanguineous Saudi Arabian families. We localized the disease gene to 16q12-21 by using members of these families for a genome-wide search for homozygous-by-descent microsatellite markers. Haplotype analysis narrowed the critical region to a 1.2-cM region that spans the gene encoding MMP-2 (gelatinase A, collagenase type IV; (ref. 3). We detected no MMP2 enzymatic activity in the serum or fibroblasts of affected family members. We identified two family-specific homoallelic MMP2 mutations: R101H and Y244X. The nonsense mutation effects a deletion of the substrate-binding and catalytic sites and the fibronectin type II-like and hemopexin/TIMP2 binding domains. Based on molecular modeling, the missense mutation disrupts hydrogen bond formation within the highly conserved prodomain adjacent to the catalytic zinc ion.