全文获取类型
收费全文 | 28982篇 |
免费 | 159篇 |
国内免费 | 114篇 |
专业分类
系统科学 | 239篇 |
丛书文集 | 293篇 |
教育与普及 | 48篇 |
理论与方法论 | 125篇 |
现状及发展 | 13477篇 |
研究方法 | 1103篇 |
综合类 | 13675篇 |
自然研究 | 295篇 |
出版年
2012年 | 480篇 |
2011年 | 746篇 |
2010年 | 140篇 |
2009年 | 137篇 |
2008年 | 385篇 |
2007年 | 449篇 |
2006年 | 474篇 |
2005年 | 650篇 |
2004年 | 1010篇 |
2003年 | 874篇 |
2002年 | 592篇 |
2001年 | 841篇 |
2000年 | 903篇 |
1999年 | 584篇 |
1992年 | 494篇 |
1991年 | 384篇 |
1990年 | 425篇 |
1989年 | 398篇 |
1988年 | 392篇 |
1987年 | 417篇 |
1986年 | 442篇 |
1985年 | 568篇 |
1984年 | 440篇 |
1983年 | 377篇 |
1982年 | 364篇 |
1981年 | 373篇 |
1980年 | 382篇 |
1979年 | 945篇 |
1978年 | 792篇 |
1977年 | 678篇 |
1976年 | 605篇 |
1975年 | 645篇 |
1974年 | 830篇 |
1973年 | 665篇 |
1972年 | 724篇 |
1971年 | 857篇 |
1970年 | 1060篇 |
1969年 | 815篇 |
1968年 | 830篇 |
1967年 | 816篇 |
1966年 | 677篇 |
1965年 | 553篇 |
1964年 | 212篇 |
1959年 | 269篇 |
1958年 | 477篇 |
1957年 | 333篇 |
1956年 | 270篇 |
1955年 | 264篇 |
1954年 | 258篇 |
1948年 | 182篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Evolution and ecological correlates of uniparental reproduction in freshwater snails 总被引:1,自引:0,他引:1
S. G. Johnson C. M. Lively S. J. Schrag 《Cellular and molecular life sciences : CMLS》1995,51(5):498-509
We review the spatial and temporal correlates of uniparental reproduction in freshwater snails as they pertain to the ecological hypotheses for the maintenance of biparental sex. The biogeographic evidence from two species (Potamopyrgus antipodarum andBulinus truncatus) presently supports the Red Queen hypothesis that biparental reproduction is selected as a way to reduce the risk to progeny of parasite attack. Uniparental reproduction in these species is associated with low levels of infection by parasites (castrating digenetic trematodes), suggesting that parthenogenesis or self-fertilization can replace cross-fertilization when the risk of infection is low. In addition, inB. truncatus, the opportunity for cross-fertilization coincides with the season in which parasite attack is highest. In a third species (Campeloma decisum), parthenogenetic reproduction is correlated with latitude and the presence of a non-castrating trematode that may prevent cross-fertilization; these patterns suggest that parthenogenesis has been selected as a mechanism to assure reproduction. Finally, we discuss the spotty taxonomic distribution of parthenogenetic species. 相似文献
992.
In several rat models, including those with circular and semicircular rectal aganglionosis, the rectosphincteric reflex was examined. The reflex was confirmed to be essentially an intramural one and its route is considered to run mainly in the longitudinal and partly in the oblique directions. 相似文献
993.
Comparative distribution of vasoactive intestinal polypeptide (VIP), substance P and PHI in the enteric sphincters of the cat 总被引:2,自引:0,他引:2
G P McGregor A E Bishop M A Blank N D Christofides Y Yiangou J M Polak S R Bloom 《Experientia》1984,40(5):469-471
In the feline gastrointestinal tract, the neuropeptides, substance P, VIP and PHI were investigated by specific radioimmunoassays and immunocytochemistry. The concentrations of all 3 peptides and the level of peptidergic innervation were significantly less in the anal sphincter than elsewhere, whereas no significant differences were seen between other sphincter and non-sphincter regions. 相似文献
994.
Summary Viscero-somatic reflexes have been studied by recording monosynaptic reflexes following distension of the urinary bladder in intact, decerebrate and spinal animals. It was observed that the viscero-somatic responses following bladder distension are inhibitory in nature and this inhibition was highest in decerebrates and least in spinal animals. The site of viscero-somatic interaction probably lies in the bulbar area (supraspinal) and spinal cord.Acknowledgment. The work was carried out with the financial assistance of the Indian Council of Medical Research, Govt of India. We are thankful to A. T. Pradhan, Abott Laboratories (India) Pvt. Ltd. for a generous supply of Nembutal. 相似文献
995.
G. P. Rao A. K. S. Baghel R. K. Singh K. S. Chatterji 《Cellular and molecular life sciences : CMLS》1984,40(11):1257-1258
Summary Crude coralloid root extract ofCycas revoluta showed significant antiviral activity against viruses of the tomato plant (PVX, PVY, TMV, TAV and TRSV) when applied 24 h before virus inoculation, or when mixed with different virus inocula before virus inocultion, in hypersensitive and systemic hosts. No such inhibition was observed when extract was applied 24 h after virus inoculation. TAV did not show any inhibitory response in a systemic host.Authors are thankful to Dr S. N. Gupta and Dr (Smt.) K. Shukla for their valuable guidance and providing laboratory facilities and U.G.C. for financial assistance. 相似文献
996.
Summary The freshwater catfishClarias batrachus (L.), exposed to 50 ppm of cadmium (Cd) chloride for a period of 135 days exhibited marked inhibition of brain monoamine oxidase (MAO) (p<0.001). The retarded gonadal growth observed in the present study suggests that Cd may be capable of creating imbalance in the aminergic activity of the hypothalamus, which modulates the secretion and release of gonadotropins.Acknowledgment. Financial assistance from the Council of Scientific and Industrial Research of India made this work possible. 相似文献
997.
998.
Summary The eggs of a sea hare,Aplysia kurodai, contained antibacterial factors which probably play a role in the defense of eggs against bacterial infection. The active factors were composed of several heat-labile proteins, unrelated to lysozyme, and were produced in the albumen gland. 相似文献
999.
J. A. Ruth M. J. Gershten J. K. Disbrow 《Cellular and molecular life sciences : CMLS》1984,40(7):692-694
Summary The accumulation of3H-dopamine by synaptic vesicles from rat striatum was significantly stabilized in a membrane impermeant medium. The characteristics of dopamine accumulation by striatal vesicles were quite similar to those reported for dopamine accumulation by a whole brain vesicle preparation in the same medium, and were siginificantly different from the characteristics previously reported for vesicular accumulation of norepinephrine.Acknowledgments. This work was supported by grant NS 18752 (NIH) of the United States Public Health Service. Reprint requests to J. A. R. 相似文献
1000.
Optically active benzo[c]phenanthrene diol epoxides bind extensively to adenine in DNA 总被引:2,自引:0,他引:2
Reactions of diol epoxide metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA are thought to initiate the carcinogenic process. Although formation of a benzo[a]pyrene (BaP) diol epoxide-deoxyguanosine adduct has been held responsible for biological activity, the more potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) binds extensively to deoxyadenosine residues in DNA, suggesting that hydrocarbon carcinogen-deoxyadenosine adducts may be instrumental in tumour initiation. Because the bay region diol epoxides of benzo[c]phenanthrene (BcPh) are very active tumour initiators, and the relative activities of the four configurationally isomeric 3,4-diol 1,2-epoxides (Fig. 1) are known, we examined their reactions with DNA. Each BcPh diol epoxide isomer exhibits a remarkable preference for covalent binding to DNA over hydrolysis, each yields a unique distribution of products with the nucleosides of DNA and each reacts extensively with deoxyadenosine residues in DNA. The relative tumour initiating activities of these stereoisomers is best reflected by the relative yields of one of the deoxyadenosine adducts formed. 相似文献