胆汁酸及FXR在细胞增生和分化中的作用研究进展

 胆汁酸具有多种重要的生理功能,不仅与脂类物质的消化吸收密切相关,还可作为激素样信号分子在胆汁酸、脂类与糖类物质代谢及能量代谢等方面发挥重要作用。近年研究发现,胆汁酸及其核受体法尼酯X受体（FXR）在细胞增生、分化、凋亡和肝再生的调控中也发挥重要作用。本文综述了胆汁酸及其核受体FXR在细胞增生、分化、凋亡和肝再生的作用及机制,以及在寄生虫-细粒棘球绦虫成虫发育分化中作用的研究进展。     

Robust H∞ controller design for sampled-data systems with parametric uncertainties

This article investigates the problem of robust H∞ controller design for sampled-data systems with time-varying norm-bounded parameter uncertainties in the state matrices. Attention is focused on the design of a causal sampled-data controller, which guarantees the asymptotical stability of the closed-loop system and reduces the effect of the disturbance input on the controlled output to a prescribed H∞ performance bound for all admissible uncertainties. Sufficient condition for the solvability of the problem is established in terms of linear matrix inequalities (LMIs). It is shown that the desired H∞ controller can be constructed by solving certain LMIs. An illustrative example is given to demonstrate the effectiveness of the proposed method.     

黑龙江省税收占GDP比重的对策研究

黑龙江省税收收入占GDP的比重偏低,已经影响到政府正常履行其基本职能。分析税收收入占GDP比重逐年下降的原因,提出了振兴经济、涵养税源、合理划分税权、规范分税制、强化税收调控职能,积极推行“费改税”,依法治税,以提高税收占GDP比重的对策。     

One Fire Detection Method Using Neural Networks

A neural network fire detection method was developed using detection information for temperature,smoke density,and CO concentration to determine the probability of three representative fire conditions.The method overcomes the shortcomings of domestic fire alarm systems using single sensor information.Test results show that the identification error rates for fires,smoldering fires,and no fire are less than 5%,which greatly reduces leak-check rates and false alarms.This neural network fire alarm system can fu...     

Mixed H2/H∞ Control Using a Fuzzy Singularly Perturbed Model with Multiple Perturbation Parameters for Gust Load Alleviation

This paper presents a mixed H2/H∞ control using fuzzy singularly perturbed model (FSPM) with multiple perturbation parameters. Since FSPM with multiple perturbation parameters is an extension of models with a single perturbation parameter, the theoretical results are applicable to a larger class of systems described by multiple time scale nonlinear models, such as flying aircraft and flexible space robots. The parameter-independent solution of the mixed H2/H∞ controller was obtained in the form of linear matrix inequalities (LMIs). The application of this approach to gust load alleviation of a flying vehicle verifies its effectiveness and flexibility.     

基于正交多项式神经网络的卫星网络QoS路由算法

QoS路由问题作为多目标约束优化问题,是一种非确定多项式完全(NP-complete)问题,目前在地面网络中多使用启发式算法求解。卫星网络的拓扑时变特性要求路由算法快速收敛,而高昂的信息交换代价又要求尽量减少星间控制信息交换,这导致绝大多数探测导向型的启发式路由算法应用在星上时性能不高。该文引入一种基于正交多项式神经网络的卫星网络QoS路由算法,将数据包路由过程类比为在经训练过的神经网络中分类的过程;同时正交多项式的使用提高了训练速率,保证了拓扑周期内训练结果的有效性。仿真结果表明:该路由算法在满足用户QoS需求的同时还降低了链路拥塞、丢包率、呼叫阻塞率等指标。     

基于视觉特性的无参考型遥感图像质量评价方法

影响遥感图像成像质量的主要是模糊和噪声这2种失真因素,二者在空域和频域互相影响互相抑制,因此很难对同时存在这2种失真的遥感图像进行客观图像质量评价。该文利用人类视觉系统对模糊和噪声两种激励的响应特性不同,结合结构相似性度量方法,提出了一种基于视觉特性的无参考型图像质量评价方法。该方法同时考虑了模糊和噪声两方面因素,它不需要参考图像作为图像质量评价依据。实验结果表明:该方法的评价结果与全参考型图像质量评价方法的结果具有较高的相关性,是一种准确可靠的无参考型图像质量评价方法,并且易于实现。     

高锰酸盐预氧化与PAM联用处理微污染水的工程研究

某地表水源取自太湖某支流,具有低浊、有机物含量高等微污染的特点。以此地表水为试验原水,提出了高锰酸盐预氧化与聚丙烯酰胺（PAM）联用强化技术。通过小试试验确定了二者具有对浊度和耗氧量的较好的去除效果,据确定生产性试验参数。生产试验结果表明,两者联用后能明显改善水质,出厂水浊度达标率从联用前的15%提高到了82%;联用后沉后水的耗氧量即低于联用前滤后水的耗氧量水平,沉后水的耗氧量的去除率达到43.00%。     

基于变密度法的山地自行车关键连接结构件拓扑优化设计

针对山地自行车减震器端和车架连接端的关键结构部件的轻量化设计问题,构建等比例三维实体模型,并采用变密度理论的拓扑优化方法,以最大化刚度为优化目标,以设计空间总体积和质量作为约束条件,对山地自行车结构部件进行拓扑优化再设计。优化求解获得一个新型的连接结构件,并对该结构在实际工况下的Mises应力、最大位移和安全系数等进行仿真校核,通过优化前后结构的分析结果综合对比,发现在保证结构部件强度、可靠性的前提下,该结构部件实现减重约50%,极大节省材料消耗。