局域网网络安全管理技术分析

安全问题始终是制约局域网进一步推广的关键因素,文章分析现今局域网网络安全威胁的因素,以及相关的安全管理技术.     

精神因素导致不孕不育临床调查及治疗

近年来不孕不育患者发病率逐年升高,不孕妇女的沮丧情绪一般会在不孕的第二到第三年之间达到顶点。但是,由于她本身和家人都把注意力放到了解决不孕这个问题上,从而忽视了精神层面。而且,大夫也反对准备怀孕的妇女服用抗抑郁症药物,因为这一类药物会导致不孕,所以精神安慰治疗以心理开导干预的手段介入不孕妇女的精神问题。当然,女性在不孕的第一年就应该考虑到自己是否该减压了,越早接受治疗效果越好。     

矿务局网络规划

局域网是一个覆盖单位所有建筑和机构的综合网络。网络建设总体目标是采用先进实用的网络通信技术和计算机技术,文章从组网图、组网设备分析、网络结构分析等方面对校园网的规划做一介绍。     

An integrated semiconductor device enabling non-optical genome sequencing

The seminal importance of DNA sequencing to the life sciences, biotechnology and medicine has driven the search for more scalable and lower-cost solutions. Here we describe a DNA sequencing technology in which scalable, low-cost semiconductor manufacturing techniques are used to make an integrated circuit able to directly perform non-optical DNA sequencing of genomes. Sequence data are obtained by directly sensing the ions produced by template-directed DNA polymerase synthesis using all-natural nucleotides on this massively parallel semiconductor-sensing device or ion chip. The ion chip contains ion-sensitive, field-effect transistor-based sensors in perfect register with 1.2 million wells, which provide confinement and allow parallel, simultaneous detection of independent sequencing reactions. Use of the most widely used technology for constructing integrated circuits, the complementary metal-oxide semiconductor (CMOS) process, allows for low-cost, large-scale production and scaling of the device to higher densities and larger array sizes. We show the performance of the system by sequencing three bacterial genomes, its robustness and scalability by producing ion chips with up to 10 times as many sensors and sequencing a human genome.     

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

Autism spectrum disorders (ASDs) comprise a range of disorders that share a core of neurobehavioural deficits characterized by widespread abnormalities in social interactions, deficits in communication as well as restricted interests and repetitive behaviours. The neurological basis and circuitry mechanisms underlying these abnormal behaviours are poorly understood. SHANK3 is a postsynaptic protein, whose disruption at the genetic level is thought to be responsible for the development of 22q13 deletion syndrome (Phelan-McDermid syndrome) and other non-syndromic ASDs. Here we show that mice with Shank3 gene deletions exhibit self-injurious repetitive grooming and deficits in social interaction. Cellular, electrophysiological and biochemical analyses uncovered defects at striatal synapses and cortico-striatal circuits in Shank3 mutant mice. Our findings demonstrate a critical role for SHANK3 in the normal development of neuronal connectivity and establish causality between a disruption in the Shank3 gene and the genesis of autistic-like behaviours in mice.     

Characterization and Preparation of Bimetallic Nanoparticles

1 Results Bimetallic particles in the nanometer size range are of substantial interest due to their vast applications in catalysis[1].The synthesis of bimetallic nanoparticles with definite size with a well-control over their nanostructure remains a challenging problem.Thus there exists a great demand for both synthesis and atomic level characterization of nanostructure of bimetallic nanoparticles (NPs).With the recent advent of high-intensity tunable sources of X-rays,now available at synchrotron radia...     

粮食产量影响因素的灰色关联分析及其贡献率比较

运用灰色关联分析的方法,通过对省域(河南省)、市域(安阳市)、县域(滑县)三级粮食产量影响因素(播种面积、有效灌溉面积、农村用电、农用化肥、农用柴油、农药)的灰色关联分析及其贡献率比较,结果表明:有效灌溉面积对市域、省域两级粮食产量的影响均居第一位,农用化肥施用量对县域、市域两级粮食产量的影响均居第二位,农药与其它5个因素相比,对省、市、县三级粮食产量的影响相同,都是最小.农用柴油、农村用电、农用化肥、农药对县、市两级粮食产量的贡献率均居第一、第二、第三、第四位,化肥和农药对省、市、县三级粮食产量的贡献率都据第三和第四位.在此基础上,为不同区域尺度的粮食生产提供了决策依据.表5.参11.     

Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL

Resequencing genes provides the opportunity to assess the full spectrum of variants that influence complex traits. Here we report the first application of resequencing to a large population (n = 3,551) to examine the role of the adipokine ANGPTL4 in lipid metabolism. Nonsynonymous variants in ANGPTL4 were more prevalent in individuals with triglyceride levels in the lowest quartile than in individuals with levels in the highest quartile (P = 0.016). One variant (E40K), present in approximately 3% of European Americans, was associated with significantly lower plasma levels of triglyceride and higher levels of high-density lipoprotein cholesterol in European Americans from the Atherosclerosis Risk in Communities Study and in Danes from the Copenhagen City Heart Study. The ratio of nonsynonymous to synonymous variants was higher in European Americans than in African Americans (4:1 versus 1.3:1), suggesting population-specific relaxation of purifying selection. Thus, resequencing of ANGPTL4 in a multiethnic population allowed analysis of the phenotypic effects of both rare and common variants while taking advantage of genetic variation arising from ethnic differences in population history.     

Ciliary proteins Fap43 and Fap44 interact with each other and are essential for proper cilia and flagella beating

Cilia beating is powered by the inner and outer dynein arms (IDAs and ODAs). These multi-subunit macrocomplexes are arranged in two rows on each outer doublet along the entire cilium length, except its distal end. To generate cilia beating, the activity of ODAs and IDAs must be strictly regulated locally by interactions with the dynein arm-associated structures within each ciliary unit and coordinated globally in time and space between doublets and along the axoneme. Here, we provide evidence of a novel ciliary complex composed of two conserved WD-repeat proteins, Fap43p and Fap44p. This complex is adjacent to another WD-repeat protein, Fap57p, and most likely the two-headed inner dynein arm, IDA I1. Loss of either protein results in altered waveform, beat stroke and reduced swimming speed. The ciliary localization of Fap43p and Fap44p is interdependent in the ciliate Tetrahymena thermophila.     

基于DEA模型的电子商务网站综合评价与质量诊断

在网络经济时代,电子商务网站运行效率直接关系到企业的生存和发展.电子商务网站评价作为比较网站优劣、指导网站建设的重要方法和手段,受到电子商务领域学术界和企业界的共同关注.本文提出基于DEA的电子商务综合评价与质量诊断方法.该方法避免了各种指标权重确定方法的主观性和不确定性,并在评价基础上对弱DEA有效和非DEA有效商务网站进行质量诊断,指明改进和提高效率的方法与途径.实例分析证实了该方法的有效性和科学性.本文的研究丰富了电子商务评价理论,为当前电子商务网站评价提供了切实可行的技术经济分析方法.