全文获取类型
收费全文 | 419篇 |
免费 | 1篇 |
国内免费 | 2篇 |
专业分类
系统科学 | 13篇 |
丛书文集 | 1篇 |
理论与方法论 | 15篇 |
现状及发展 | 70篇 |
研究方法 | 56篇 |
综合类 | 247篇 |
自然研究 | 20篇 |
出版年
2022年 | 1篇 |
2021年 | 2篇 |
2020年 | 1篇 |
2019年 | 1篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 6篇 |
2015年 | 5篇 |
2014年 | 3篇 |
2013年 | 8篇 |
2012年 | 32篇 |
2011年 | 48篇 |
2010年 | 17篇 |
2009年 | 4篇 |
2008年 | 37篇 |
2007年 | 42篇 |
2006年 | 30篇 |
2005年 | 25篇 |
2004年 | 22篇 |
2003年 | 33篇 |
2002年 | 22篇 |
2001年 | 4篇 |
2000年 | 6篇 |
1999年 | 2篇 |
1997年 | 1篇 |
1996年 | 2篇 |
1994年 | 3篇 |
1992年 | 1篇 |
1991年 | 4篇 |
1990年 | 4篇 |
1989年 | 7篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1979年 | 1篇 |
1978年 | 2篇 |
1977年 | 5篇 |
1976年 | 2篇 |
1975年 | 5篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1971年 | 2篇 |
1970年 | 2篇 |
1968年 | 1篇 |
1967年 | 3篇 |
1966年 | 1篇 |
1962年 | 2篇 |
1961年 | 1篇 |
1960年 | 1篇 |
排序方式: 共有422条查询结果,搜索用时 15 毫秒
91.
92.
93.
鉴于目前没有一种方法能独立解决溢油鉴别的所有问题[1],本文提出近红外光谱技术结合主成分聚类分析鉴别溢油种类的方法.通过有机溶剂萃取出自行配制的汽油、柴油和润滑油模拟样品中的溢油后记录其近红外光谱,对5 800~6 200 cm-1区段范围内的近红外谱图经过多元散射校正(MSC),Norris一阶导数平滑预处理处理后求其主成分,并在主成分的基础上引入Ward聚类分析法(离差平方和法)对样品分类. 相似文献
94.
95.
Business organisations have always existed in a constantly changing environment. To survive it is necessary for them to adapt and adjust to the changes. When analysing complex entities, such as organisations, researchers have frequently adopted the methods of action research. But with the advent of greater use of information and communication technology businesses are changing in their composition and one practical manifestation of this is the rise of virtual teams. Virtual teams reflect the trend for an organisation to comprise ‘satellites’ or clusters of expertise in different parts of the globe. Such a transformation of what we can now take as an organisation creates new challenges for managers and for those inquiring into organisational problems. In this paper we attempt to address the question whether action research is any longer a valid way of organisational intervention for the researcher and consultant alike. In this paper we describe field research in which a soft method of Action Research was used during the analysis phase of IS development as a means of understanding the problem domain, identifying information requirements, evaluating technologies and reducing conflicts. The research was conducted between two institutions that were separated by several thousand miles and all participants connected from individual locations using virtual synchronous ICT. The study provided insight into the use of AR in virtual settings and as a means of conflict resolution in virtual teams. The findings have implications for IS development (which is increasingly conducted in virtual teams), education and management among others. 相似文献
96.
97.
Identification of ten loci associated with height highlights new biological pathways in human growth 总被引:1,自引:0,他引:1
Lettre G Jackson AU Gieger C Schumacher FR Berndt SI Sanna S Eyheramendy S Voight BF Butler JL Guiducci C Illig T Hackett R Heid IM Jacobs KB Lyssenko V Uda M;Diabetes Genetics Initiative;FUSION;KORA;Prostate Lung Colorectal Ovarian Cancer Screening Trial;Nurses' Health Study;SardiNIA Boehnke M Chanock SJ Groop LC Hu FB Isomaa B Kraft P Peltonen L Salomaa V Schlessinger D Hunter DJ Hayes RB Abecasis GR Wichmann HE Mohlke KL Hirschhorn JN 《Nature genetics》2008,40(5):584-591
Height is a classic polygenic trait, reflecting the combined influence of multiple as-yet-undiscovered genetic factors. We carried out a meta-analysis of genome-wide association study data of height from 15,821 individuals at 2.2 million SNPs, and followed up the strongest findings in >10,000 subjects. Ten newly identified and two previously reported loci were strongly associated with variation in height (P values from 4 x 10(-7) to 8 x 10(-22)). Together, these 12 loci account for approximately 2% of the population variation in height. Individuals with < or =8 height-increasing alleles and > or =16 height-increasing alleles differ in height by approximately 3.5 cm. The newly identified loci, along with several additional loci with strongly suggestive associations, encompass both strong biological candidates and unexpected genes, and highlight several pathways (let-7 targets, chromatin remodeling proteins and Hedgehog signaling) as important regulators of human stature. These results expand the picture of the biological regulation of human height and of the genetic architecture of this classical complex trait. 相似文献
98.
99.
Thiamine is an essential cofactor that is required for processes of general metabolism amongst all organisms, and it is likely to have played a role in the earliest stages of the evolution of life. Here, we review from a structural perspective the enzymatic mechanisms that involve this cofactor. We explore asymmetry within homodimeric thiamine diphosphate (ThDP)-dependent enzyme structures and discuss how this may be correlated with the kinetic properties of half-of-the-sites reactivity, and negative cooperativity. It is likely these structural and kinetic hallmarks may arise through reciprocal coupling of active sites. This mode of communication between distant active sites is not unique to ThDP-dependent enzymes, but is widespread in other classes of oligomeric enzyme. Thus, it appears likely to be a general phenomenon reflecting a powerful mechanism of accelerating the rate of a chemical pathway. Finally, we speculate on the early evolutionary history of the cofactor and its ancient association with protein and RNA. 相似文献
100.