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411.
The origin and evolution of planetary rings is one of the prominent unsolved problems of planetary sciences, with direct implications for planet-forming processes in pre-planetary disks. The recent detection of four propeller-shaped features in Saturn's A ring proved the presence of large boulder-sized moonlets in the rings. Their existence favours ring creation in a catastrophic disruption of an icy satellite rather than a co-genetic origin with Saturn, because bodies of this size are unlikely to have accreted inside the rings. Here we report the detection of eight new propeller features in an image sequence that covers the complete A ring, indicating embedded moonlets with radii between 30 m and 70 m. We show that the moonlets found are concentrated in a narrow 3,000-km-wide annulus 130,000 km from Saturn. Compared to the main population of ring particles (radius s < 10 m), such embedded moonlets have a short lifetime with respect to meteoroid impacts. Therefore, they are probably the remnants of a shattered ring-moon of Pan size or larger, locally contributing new material to the older ring. This supports the theory of catastrophic ring creation in a collisional cascade. 相似文献
412.
Lande R Gregorio J Facchinetti V Chatterjee B Wang YH Homey B Cao W Wang YH Su B Nestle FO Zal T Mellman I Schröder JM Liu YJ Gilliet M 《Nature》2007,449(7162):564-569
Plasmacytoid dendritic cells (pDCs) sense viral and microbial DNA through endosomal Toll-like receptors to produce type 1 interferons. pDCs do not normally respond to self-DNA, but this restriction seems to break down in human autoimmune disease by an as yet poorly understood mechanism. Here we identify the antimicrobial peptide LL37 (also known as CAMP) as the key factor that mediates pDC activation in psoriasis, a common autoimmune disease of the skin. LL37 converts inert self-DNA into a potent trigger of interferon production by binding the DNA to form aggregated and condensed structures that are delivered to and retained within early endocytic compartments in pDCs to trigger Toll-like receptor 9. Thus, our data uncover a fundamental role of an endogenous antimicrobial peptide in breaking innate tolerance to self-DNA and suggest that this pathway may drive autoimmunity in psoriasis. 相似文献
413.
Magnani F Mencuccini M Borghetti M Berbigier P Berninger F Delzon S Grelle A Hari P Jarvis PG Kolari P Kowalski AS Lankreijer H Law BE Lindroth A Loustau D Manca G Moncrieff JB Rayment M Tedeschi V Valentini R Grace J 《Nature》2007,447(7146):848-850
Temperate and boreal forests in the Northern Hemisphere cover an area of about 2 x 10(7) square kilometres and act as a substantial carbon sink (0.6-0.7 petagrams of carbon per year). Although forest expansion following agricultural abandonment is certainly responsible for an important fraction of this carbon sink activity, the additional effects on the carbon balance of established forests of increased atmospheric carbon dioxide, increasing temperatures, changes in management practices and nitrogen deposition are difficult to disentangle, despite an extensive network of measurement stations. The relevance of this measurement effort has also been questioned, because spot measurements fail to take into account the role of disturbances, either natural (fire, pests, windstorms) or anthropogenic (forest harvesting). Here we show that the temporal dynamics following stand-replacing disturbances do indeed account for a very large fraction of the overall variability in forest carbon sequestration. After the confounding effects of disturbance have been factored out, however, forest net carbon sequestration is found to be overwhelmingly driven by nitrogen deposition, largely the result of anthropogenic activities. The effect is always positive over the range of nitrogen deposition covered by currently available data sets, casting doubts on the risk of widespread ecosystem nitrogen saturation under natural conditions. The results demonstrate that mankind is ultimately controlling the carbon balance of temperate and boreal forests, either directly (through forest management) or indirectly (through nitrogen deposition). 相似文献
414.
Biskup C Kusch J Schulz E Nache V Schwede F Lehmann F Hagen V Benndorf K 《Nature》2007,446(7134):440-443
Cyclic nucleotide-gated (CNG) ion channels mediate sensory signal transduction in photoreceptors and olfactory cells. Structurally, CNG channels are heterotetramers composed of either two or three homologue subunits. Although it is well established that activation is a cooperative process of these subunits, it remains unknown whether the cooperativity is generated by the ligand binding, the gating, or both, and how the subunits interact. In this study, the action of homotetrameric olfactory-type CNGA2 channels was studied in inside-out membrane patches by simultaneously determining channel activation and ligand binding, using the fluorescent cGMP analogue 8-DY547-cGMP as the ligand. At concentrations of 8-DY547-cGMP < 1 microM, steady-state binding was larger than steady-state activation, whereas at higher concentrations it was smaller, generating a crossover of the steady-state relationships. Global analysis of these relationships together with multiple activation time courses following cGMP jumps showed that four ligands bind to the channels and that there is significant interaction between the binding sites. Among the binding steps, the second is most critical for channel opening: its association constant is three orders of magnitude smaller than the others and it triggers a switch from a mostly closed to a maximally open state. These results contribute to unravelling the role of the subunits in the cooperative mechanism of CNGA2 channel activation and could be of general relevance for the action of other ion channels and receptors. 相似文献
415.
Marine ecology: Spring algal bloom and larval fish survival 总被引:2,自引:0,他引:2
416.
秸秆炭低温燃烧可抑制灰中的钾、钠、氯等的逸出,减少结渣、沾污和气相颗粒物的排放.为明确低温下炭氧化过程主要特性,采用同步热分析仪对玉米秸炭进行了实验.根据热流及失重速率曲线,确定了玉米秸炭低温燃烧温度范围,分析了燃烧温度、空气流量、堆积尺寸对CO/CO2值的影响,计算了动力学参数、堆积燃烧速率(燃尽时间).结果表明:玉米秸炭低温燃烧可采用500~680℃;CO/CO2值随温度的升高先增加后减小,增大空气流量、减小堆积尺寸均会降低CO/CO2值;秸秆炭动力燃烧时,在500、550、600、650℃下转化90%时所需时间分别为6.8、2.2、0.8、0.3 min.堆积燃烧时,500~680℃内,200 mL/min空气流量下,3、5、8 mg炭燃尽时间分别为15、18、25 min.以上结论可为玉米秸炭低温燃烧设备的设计提供依据. 相似文献