Points of View Beyond Models: Towards a Formal Approach to Points of View as Access to the World

According to Vázquez and Liz (Found Sci 16(4): 383–391, 2011), Points of View (PoV) can be considered in two different ways. On the one hand, they can be explained following the model of propositional attitudes. This model assumes that the internal structure of a PoV is constituted by a subject, a set of contents, and a set of relations between the subject and those contents. On the other hand, we can analyze points of view taking as a model the notions of location and access. If we choose to follow the second approach, instead of the first one, the internal structure of a PoV is not directly addressed, and the emphasized features of PoV are related to the function that PoV are intended to have. That is, PoV are directly identified by their role and they can solely be understood as ways of accessing the world that bring some kind of perspective about it. Having this in mind, we would like to propose a notation that explains how to understand such access as a sort of models (that can allow the creation of concepts), independently of whether the precise PoV under consideration is impersonal or non-impersonal, its kind of content, and its subjective or objective character. First, we will present an account of some previous approaches to the study of points of view. Then, we will analyze what kind of structure the world is assumed to posses and how the access to it is possible. Third, we will develop a notation that explains PoV as qualitative dimensions by means of which it is possible to valuate objects and states of the world.     

Improving moving average trading rules with boosting and statistical learning methods

We present a system for combining the different types of predictions given by a wide category of mechanical trading rules through statistical learning methods (boosting, and several model averaging methods like Bayesian or simple averaging methods). Statistical learning methods supply better out‐of‐sample results than most of the single moving average rules in the NYSE Composite Index from January 1993 to December 2002. Moreover, using a filter to reduce trading frequency, the filtered boosting model produces a technical strategy which, although it is not able to overcome the returns of the buy‐and‐hold (B&H) strategy during rising periods, it does overcome the B&H during falling periods and is able to absorb a considerable part of falls in the market. Copyright © 2008 John Wiley & Sons, Ltd.     

幂权Beurling代数上的次线性算子

建立了Ｂｅｕｒｌｉｎｇ代数的分解特征．这个特征被用来对一大类次线性算子建立它们在幂权Ｂｅｕｒｌｉｎｇ代数上的有界性质，而对于无权情形此结论却不成立．     

A complexity architecture for information technologies: A three-year didactic experiment

One medium-term strategy for helping in the management of complexity is the introduction of a conceptual complexity component in the very centre of university curricula. In very few areas is the growth of complexity as evident as in the information technologies (ITs), the focus of the work presented in the current paper. We have therefore developed an integrated way of tackling the specific field of information technologies by means of an approach to complexity. The content of this paper describes the guidelines of our research effort, placing an emphasis on informatics. Concepts of complexity based on the system metaphor have been substantially drawn upon in this exercise and are thus presented in some detail. Also described is a didactic experiment conducted by the author and designed to provide a new and integrating approach to University curricula for future professionals. The students' discovery of complexity is the focal point of the experiment. The findings of this effort are encouraging and call for the continuation and expansion of this experiment.     

Cluster Differences Unfolding for Two-Way Two-Mode Preference Rating Data

Classification and spatial methods can be used in conjunction to represent the individual information of similar preferences by means of groups. In the context of latent class models and using Simulated Annealing, the cluster-unfolding model for two-way two-mode preference rating data has been shown to be superior to a two-step approach of first deriving the clusters and then unfolding the classes. However, the high computational cost makes the procedure only suitable for small or medium-sized data sets, and the hypothesis of independent and normally distributed preference data may also be too restrictive in many practical situations. Therefore, an alternating least squares procedure is proposed, in which the individuals and the objects are partitioned into clusters, while at the same time the cluster centers are represented by unfolding. An enhanced Simulated Annealing algorithm in the least squares framework is also proposed in order to address the local optimum problem. Real and artificial data sets are analyzed to illustrate the performance of the model.     

Supramolecular self-assembled molecules as organic directing agent for synthesis of zeolites

Solid materials with uniform micropores, such as zeolites, can act as selective catalysts and adsorbents for molecular mixtures by separating those molecules small enough to enter their pores while leaving the larger molecules behind. Zeolite A is a microporous material with a high void volume. Despite its widespread industrial use in, for example, molecular separations and in detergency, its capability as a petroleum-refining material is limited owing to its poor acid-catalytic activity and hydrothermal stability, and its low hydrophobicity. These characteristics are ultimately a consequence of the low framework Si/Al ratio (normally around one) and the resulting high cationic fraction within the pores and cavities. Researchers have modified the properties of type-A zeolites by increasing the Si/Al compositions up to a ratio of three. Here we describe the synthesis of zeolite A structures exhibiting high Si/Al ratios up to infinity (pure silica). We synthesize these materials, named ITQ-29, using a supramolecular organic structure-directing agent obtained by the self-assembly, through pi-pi type interactions, of two identical organic cationic moieties. The highly hydrophobic pure-silica zeolite A can be used for hydrocarbon separations that avoid oligomerization reactions, whereas materials with high Si/Al ratios give excellent shape-selective cracking additives for increasing propylene yield in fluid catalytic cracking operations. We have also extended the use of our supramolecular structure-directing agents to the synthesis of a range of other zeolites.     

Two new Andean species of Anolis lizard (Iguanidae: Dactyloinae) from southern Ecuador

ABSTRACT

We describe two new species of Anolis lizard that are sympatric on the Amazonian slopes of the Andes of southern Ecuador at elevations between 1440 and 1970 m. The new species may be distinguished from other Anolis by external anatomy, mitochondrial divergence and dewlap colour. We estimate the phylogenetic positions of the new species using Bayesian analysis of DNA sequence data including all species of Dactyloa-clade Anolis for which DNA data are available. Anolis hyacintogularis sp. nov. is sister to Anolis calimae, whereas Anolis lososi sp. nov. is sister to Anolis williamsmittermeierorum, herein reported for Ecuador for the first time. Individuals of both new species were collected within a protected area in southern Ecuador, Podocarpus National Park, which suggests that at least some populations of these species are well protected.

www.zoobank.org/urn:lsid:zoobank.org:pub:E55FA804-E3FD-4412-8FEB-5234E29E272D     

Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer’s disease patients

Statins may exert beneficial effects on Alzheimer’s disease (AD) patients. Based on the antineoplastic and apoptotic effects of statins in a number of cell types, we hypothesized that statins may be able to protect neurons by controlling the regulation of cell cycle and/or apoptosis. A growing body of evidence indicates that neurodegeneration involves the cell-cycle activation in postmitotic neurons. Failure of cell-cycle control is not restricted to neurons in AD patients, but occurs in peripheral cells as well. For these reasons, we studied the role of simvastatin (SIM) on cell survival/death in lymphoblasts from AD patients. We report here that SIM induces apoptosis in AD lymphoblasts deprived of serum. SIM interacts with PI3K/Akt and ERK1/2 signaling pathways thereby decreasing the serum withdrawal-enhanced levels of the CDK inhibitor p21^Cip1 (p21) and restoring the vulnerability of AD cells to trophic factor deprivation.