学位和研究生教育质量评估支持系统的实现

本文首先分析了学位和研究生教育质量评估支持系统开发的必要性和可能性, 然后介绍了一个用于这方面的计算机支持系统, 阐明了该系统的设计和实现, 并给出了部分评估案例。     

Electrophoretic mobilities of malate dehydrogenases from barley seedlings

Zusammenfassung Malatdehydrogenase aus der Mitochondrienfraktion von Gerstenkeimlingen verhält sich elektrophoretisch verschieden von der Malatdehydrogenase aus der Cytoplasmafraktion.

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This work is supported by a research grant from the University of Hong Kong.     

Clarifying the glass-transition behaviour of water by comparison with hyperquenched inorganic glasses

The formation of glasses is normal for substances that remain liquid over a wide temperature range (the 'good glassformers') and can be induced for most liquids if cooling is fast enough to bypass crystallization. During reheating but still below the melting point, good glassformers exhibit glass transitions as they abruptly transform into supercooled liquids, whereas other substances transform directly from the glassy to the crystalline state. Whether water exhibits a glass transition before crystallization has been much debated over five decades. For the last 20 years, the existence of a glass transition at 136 K (ref. 3) has been widely accepted, but the transition exhibits qualities difficult to reconcile with our current knowledge of glass transitions. Here we report detailed calorimetric characterizations of hyperquenched inorganic glasses that, when heated, do not crystallize before reaching their glass transition temperatures. We compare our results to the behaviour of glassy water and find that small endothermic effects, such as the one attributed to the glass transition of water, are only a 'shadow' of the real glass transition occurring at higher temperatures, thus substantiating the conclusion that the glass transition of water cannot be probed directly.     

Persistent organic pollutants PCNs and PBDEs in sediments from coastal waters of Qingdao,Shandong Peninsula

Thirty-one congeners of polychlorinated naphthalenes (PCNs) and 21 congeners of polybrominated diphenylethers(PBDEs)in surface sediments at 5 stations and one mussel sample from Qingdao coastal waters were analyzed. The maximum contents occur at the station near the Haibo River mouth. The total PCNs contents are in the range of 212-1209 pg/g dw, dominated by tri-Cl CN. The total PBDEs contents are in the range of 117-5510 pg/g dw,dominated by tri- to hexa-BrBDEs. The local sources of PCNs are likely from combustion processes such as incinerations and coal burnings. The sources of PBDEs are molecular diffusion from the materials containing them. Except for the area near the river mouth where is affected by the sewage sludges, an important source of PCNs and PBDEs in this area is believed to be the atmospheric deposition. Mussels enrich PCNs and PBDEs relative to the sediments. The total TEQs of PCNs in mussels are lower than the total TEQs of PCBs.     

A mouse model of human L1 retrotransposition

The L1 retrotransposon has had an immense impact on the size and structure of the human genome through a variety of mechanisms, including insertional mutagenesis. To study retrotransposition in a living organism, we created a mouse model of human L1 retrotransposition. Here we show that L1 elements can retrotranspose in male germ cells, and that expression of a human L1 element under the control of its endogenous promoter is restricted to testis and ovary. In the mouse line with the highest level of L1 expression, we found two de novo L1 insertions in 135 offspring. Both insertions were structurally indistinguishable from natural endogenous insertions. This suggests that an individual L1 element can have substantial mutagenic potential. In addition to providing a valuable in vivo model of retrotransposition in mammals, these mice are an important step in the development of a new random mutagenesis system.     

基于MATLAB的信号与系统软件实验平台

基于MATLAB软件的信号与系统实验平台,弥补了教学中的不足,通过实验,加强学生对信号与系统课程的理解和掌握。     

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3

Programmed destruction of regulatory proteins through the ubiquitin-proteasome system is a widely used mechanism for controlling signalling pathways. Cullins are proteins that function as scaffolds for modular ubiquitin ligases typified by the SCF (Skp1-Cul1-F-box) complex. The substrate selectivity of these E3 ligases is dictated by a specificity module that binds cullins. In the SCF complex, this module is composed of Skp1, which binds directly to Cul1, and a member of the F-box family of proteins. F-box proteins bind Skp1 through the F-box motif, and substrates by means of carboxy-terminal protein interaction domains. Similarly, Cul2 and Cul5 interact with BC-box-containing specificity factors through the Skp1-like protein elongin C. Cul3 is required for embryonic development in mammals and Caenorhabditis elegans but its specificity module is unknown. Here we report the identification of a large family of BTB-domain proteins as substrate-specific adaptors for C. elegans CUL-3. Biochemical studies using the BTB protein MEL-26 and its genetic target MEI-1 (refs 12, 13) indicate that BTB proteins merge the functional properties of Skp1 and F-box proteins into a single polypeptide.     

蚂蚁觅食模型及其行为

提出一个描述蚂蚁觅食行为的计算机模拟模型,并对此模型展示的倍周期分岔行为进行解释,即由于觅食行为中个体之间信息传递和收到信息之后采取行动需要时间而引起的“信息滞后”,这是一种新观点,可以称为“信息滞后打破均衡”。     

控制与诱导结合中带时窗限制的动态配流模型

交通控制与诱导的集成一体化代表了现代交通管理的发展方向,而动态交通分配及其相关问题的研究是控制与诱导集成的重要理论基础.在现有研究成果的基础上,综合考虑了道路最大通行能力对交通配流策略的影响,从用户到达的时间要求和控制约束两方面考察了交通流到达目的地的时间限制,以系统最优的思想,建立了一种控制诱导相结合的有到达时间限制的动态配流模型,并且利用遗传算法对离散化后的模型进行了求解.模型中的时窗限制是作为已知条件来考虑的,通过对交通流的控制和诱导从而使系统达到最优.最后给出了一个具体交通网络实例,从而验证所提出的模型及算法的有效性和可行性.     

单向单交叉并行链优先约束的可靠性系统测试优化

针对具有单向单交叉并行链优先约束的可靠性系统的最优测试序列问题,提出了一种最优测试原则,该测试原则的约束条件更接近复杂的实际情况。通过证明三个相关的定理,分别解决了单向单交叉并行链优先约束的问题转化形式,相交单元在最优测试序列中测试的先后顺序,以及反“Y”形优先约束问题的最优测试序列。利用这一测试原则,可使此类系统获得总期望测试成本最小。通过一系列证明,给出了该原则的求证过程及具体步骤。