水分对头孢唑林钠药效的影响初探

用平衡湿度法测定了头孢唑林钠的临界相对湿度，在２０℃时约为６７％。同时，通过破坏性实验考察了水分对其药效的影响，初步结果表明，水分每增加１％，效价降低约０．５％。据此，提出了分装操作的若干注意事项。     

γ-Al_2O_3上CO和CO_2吸附表面体的原位红外光谱研究

本文运用原位红外光谱研究了在γ—Al_2O_3上CO、CO_2的吸附及其与H_2或H_2O的共吸附。观测到不同情况下HCOO~-的生成规律及其随温度变化的行为。在(CO+H_2)的共吸附中观察到HCO_3~-向HCOO~-表面体的转变。在(CO+H_2O)共吸附中,HCOO~-不经HCO_3~-的中间步骤而直接生成。在CO_2的吸附中,检测到两种热稳定性不同的表面HCO_3~-体。而(CO_2+H_2)共吸附中也观察到了HCOO~-的形成。研究了表面甲酸体在真空中热分解以及它同H_2或H_2O的反应,证实了表面甲酸体更易于同H_2O反应。这三种情况下甲酸体显著反应温度分别约为400℃、300℃、100℃。     

Agreement between NSFC and DFG Signed in Beijing

On Apr. 11, Prof. Chen Yiyu, on behalf of NSFC, signed the "Agreement between NSFC and DFG onsupport of Sino-German joint interdisciplinary research programs (SG-JIRP)"with visiting Prof. Winnacker,President of DFG. . The agreement aims to encourage scientists from both countries to undertake ambitious long-term research at an international level, promote interdisciplinary research and foster young researchers. It willserve as a platform for joint interdisciplinary research. Groups…     

Structure of human follicle-stimulating hormone in complex with its receptor

Follicle-stimulating hormone (FSH) is central to reproduction in mammals. It acts through a G-protein-coupled receptor on the surface of target cells to stimulate testicular and ovarian functions. We present here the 2.9-A-resolution structure of a partially deglycosylated complex of human FSH bound to the extracellular hormone-binding domain of its receptor (FSHR(HB)). The hormone is bound in a hand-clasp fashion to an elongated, curved receptor. The buried interface of the complex is large (2,600 A2) and has a high charge density. Our analysis suggests that all glycoprotein hormones bind to their receptors in this mode and that binding specificity is mediated by key interaction sites involving both the common alpha- and hormone-specific beta-subunits. On binding, FSH undergoes a concerted conformational change that affects protruding loops implicated in receptor activation. The FSH-FSHR(HB) complexes form dimers in the crystal and at high concentrations in solution. Such dimers may participate in transmembrane signal transduction.     

速滑运动员基础体温的研究——兼谈不同负荷强度时体温变化的特点

在长期跟队观察和测量的基础上,对30名优秀速滑运动员(男15名x 22.5岁,女15名x19.11岁,其中运动键将27名占90%)的基础体温及其他条件下的体温,心率和血乳酸进行初步研究。结果证明:我国速滑运动员的基础体温低于我国正常成人和其他项目运动员的均值,并表现出波动性,阶段性和专项性特点。在比赛中速滑运动员体温急剧下降,下降的幅度与滑跑速度和气温有密切的关系。速滑运动员体温的测量与评定,对评价运动员的身体机能状况和训练水平具有一定的实用价值和参考依据。     

几何对称性在变压器温度场有限元法计算中的研究

变压器铁心温度场计算模型因边界条件不具有对称性而造成计算区域为电磁场计算区域的一倍.针对这一实际问题,本文分析了利用几何对称性从已有的属于一半区域的模块运行结果直接得到全区域的相应模块的运行结果的可能性,提出了实施方案和相应程序,从理论上解决了变压器电磁场计算与温度场计算之间的良好衔接问题,并且由于大量减少CPU时间而具有实际意义。     

基于云计算的动漫产业协作模型

云计算作为一种计算模式可以通过志愿技术将用户的计算资源整合起来,动态组成虚拟化的资源提供给用户使用.云计算可以将动漫企业的软硬件资源进行集中化与标准化,提高资源的利用效率.首先分析动漫产业的发展现状和动漫产业在规模、投入及资源共享方面存在的问题,然后基于云计算的特点研究云计算可以为动漫企业带来的优势,建立一种基于云计算的动漫产业协作模型,通过动漫企业之间的协作实现资源共享和利益共享.对动漫产业建立云计算平台的途径提出对策和建议,主要集中在解决动漫产业的企业规模偏小、资金比较紧张、资源共享及资源有效利用率低等问题.     

KPb2Cl5晶体中掺杂Er3+和Eu3+离子占据格位倾向性的原子模拟研究

本文采用经验势原子方法模拟研究了稀土Er3+和Eu3+离子掺入KPb2Cl5晶体的格位占据情况,其中经验势参数通过拟合KPb2Cl5、PbCl2、ErCl3、EuCl3晶体结构得到.在此基础上,研究了KPb2Cl5晶体的本征缺陷和替代缺陷,而且通过溶解反应能计算发现,掺杂Er3+/Eu3+离子更倾向于占据Pb2格位,并由最近邻的K空位缺陷提供电荷补偿.这一结论与文献报道的KPb2Cl5:Eu3+光谱分析结果一致,为Er3+掺杂KPb2Cl5占据格位实验假设提供理论支持.     

一类奇异半正三阶三点边值问题解的存在性

笔者研究了一类三阶三点边值问题解的存在性,在非线性项半正且奇异的情况下,利用Guo—Kmsnoselskii不动点定理证明了解的存在性．     

Terahertz-field-induced insulator-to-metal transition in vanadium dioxide metamaterial

Electron-electron interactions can render an otherwise conducting material insulating, with the insulator-metal phase transition in correlated-electron materials being the canonical macroscopic manifestation of the competition between charge-carrier itinerancy and localization. The transition can arise from underlying microscopic interactions among the charge, lattice, orbital and spin degrees of freedom, the complexity of which leads to multiple phase-transition pathways. For example, in many transition metal oxides, the insulator-metal transition has been achieved with external stimuli, including temperature, light, electric field, mechanical strain or magnetic field. Vanadium dioxide is particularly intriguing because both the lattice and on-site Coulomb repulsion contribute to the insulator-to-metal transition at 340?K (ref. 8). Thus, although the precise microscopic origin of the phase transition remains elusive, vanadium dioxide serves as a testbed for correlated-electron phase-transition dynamics. Here we report the observation of an insulator-metal transition in vanadium dioxide induced by a terahertz electric field. This is achieved using metamaterial-enhanced picosecond, high-field terahertz pulses to reduce the Coulomb-induced potential barrier for carrier transport. A nonlinear metamaterial response is observed through the phase transition, demonstrating that high-field terahertz pulses provide alternative pathways to induce collective electronic and structural rearrangements. The metamaterial resonators play a dual role, providing sub-wavelength field enhancement that locally drives the nonlinear response, and global sensitivity to the local changes, thereby enabling macroscopic observation of the dynamics. This methodology provides a powerful platform to investigate low-energy dynamics in condensed matter and, further, demonstrates that integration of metamaterials with complex matter is a viable pathway to realize functional nonlinear electromagnetic composites.