多个查询时选择区域更新策略的参数设定

提出了在位置相关连续查询(LDCQ)中选择区域更新策略在多个查询存在的情况下的优化参数值的理论分析结果.通过给予不同区域内固定大小的偏差限来减少移动对象的更新次数和对计算容量的占用;同时通过延迟广播来减少广播信息数量,从而优化了系统结构,减轻了系统负荷.研究结果表明,在多个查询同时存在的情况下,SAU的优化参数选择的理论分析和结果与实际仿真结果是基本符合的.     

基于三维参数化斜Haar变换彩色图像压缩编码

提出基于三维参数化斜Haar变换的静止彩色图像压缩编码方法,采用计算复杂度低、变换效果好且变换矩阵可随参数灵活变化的新型参数化斜Haar变换,并将彩色图像的R,G,B 3个分量看作一个整体同时进行变换,不仅有效地去除了各分量内像素的相关性,还去除了各分量间的相关性.理论分析和实验结果表明:参数化斜Haar变换的重建图像质量接近于准最优的DCT变换,同时,提高了压缩比.该方法计算量较小,尤其适合于编码效率更高的16×16分块方法,可推广应用于画面质量要求不太高的实时视频编码中.     

住达三期工程沉降观测技术探讨

在住宅建设施工测绘中,使用瑞士莱卡NA2补尝式自动安平水准仪进行外业数据采集,结合威远图沉降数据处理软件进行沉降观测的技术方法,降低了施工成本,大大提高了工作效率.     

新生大鼠大脑皮层和海马神经元体外培养方法及改进

探索用24 h内新生SD大鼠进行神经元体外培养的方法.取新生SD大鼠的大脑皮层和海马,胰酶消化5～10 min后,放入含100 g/L血清的DMEM/F12培养基中培养.24 h后,更换含B27无血清培养基.以后每隔1d,半换液.结果显示绝大部分神经元于第2天长出突起,第3天神经元间形成复杂的联系,第7天神经元发育基本成熟.经神经元特异性烯醇酶(NSE)鉴定,培养细胞均为神经元,纯度可达90%以上,可以用于实验.     

基于可视化Bean和JMF的Web实时监控系统的研究

通过研究可视化Bean和JMF在Web监控领域中的应用,提出了一种利用JMF控制监控设备并捕获视频信息,以用于Web实时监控的新方法.不仅解决了从实时视频流中抽取单帧图像的关键问题,而且给出了协调监控设备与Web网页同步工作的有效方法,为实现基于Web的大规模网络实时监控提供了一种新途径.     

An Adaptive Multiscale Ensemble Learning Paradigm for Nonstationary and Nonlinear Energy Price Time Series Forecasting

For forecasting nonstationary and nonlinear energy prices time series, a novel adaptive multiscale ensemble learning paradigm incorporating ensemble empirical mode decomposition (EEMD), particle swarm optimization (PSO) and least square support vector machines (LSSVM) with kernel function prototype is developed. Firstly, the extrema symmetry expansion EEMD, which can effectively restrain the mode mixing and end effects, is used to decompose the energy price into simple modes. Secondly, by using the fine‐to‐coarse reconstruction algorithm, the high‐frequency, low‐frequency and trend components are identified. Furthermore, autoregressive integrated moving average is applicable to predicting the high‐frequency components. LSSVM is suitable for forecasting the low‐frequency and trend components. At the same time, a universal kernel function prototype is introduced for making up the drawbacks of single kernel function, which can adaptively select the optimal kernel function type and model parameters according to the specific data using the PSO algorithm. Finally, the prediction results of all the components are aggregated into the forecasting values of energy price time series. The empirical results show that, compared with the popular prediction methods, the proposed method can significantly improve the prediction accuracy of energy prices, with high accuracy both in the level and directional predictions. Copyright © 2016 John Wiley & Sons, Ltd.     

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

Epimutations in the germline, such as methylation of the MLH1 gene, may contribute to hereditary cancer syndrome in human, but their transmission to offspring has never been documented. Here we report a family with inheritance, in three successive generations, of germline allele-specific and mosaic hypermethylation of the MSH2 gene, without evidence of DNA mismatch repair gene mutation. Three siblings carrying the germline methylation developed early-onset colorectal or endometrial cancers, all with microsatellite instability and MSH2 protein loss. Clonal bisulfite sequencing and pyrosequencing showed different methylation levels in different somatic tissues, with the highest level recorded in rectal mucosa and colon cancer tissue, and the lowest in blood leukocytes. This mosaic state of germline methylation with different tissue distribution could act as the first hit and provide a mechanism for genetic disease inheritance that may deviate from the mendelian pattern and be overlooked in conventional leukocyte-based genetic diagnosis strategy.     

检测血浆纤维蛋白原含量对临床诊疗冠心病的指导意义

目的探讨血浆纤维蛋白原含量变化与冠状动脉病变严重程度的关系。方法选择AMI患者20例（AMI组）,48小时内劳力型心绞痛加剧和出现自发性心绞痛患者24例（UAP）,典型心绞痛发作,其性质在1～3个月内无法改变的SAP患者18例（SAP组）．健康对照20例,采用美国库尔特公司的ACL-9000全自动血凝分析仪,测定其血浆,进行比较分析。结果AMI组和UAP组患者的血浆纤维蛋白原含量均高于SAP组和健康对照组（P〈0.05）。但AMI组与UAP组患者之间血浆纤维蛋白原含量无显著性差异（P〉0．05）。结论血浆纤维蛋白原含量与冠状动脉病变严重程度相关,急性冠状动脉综合征时体内处于高凝状态,抗凝和溶栓治疗有助于降低冠状动脉实践的危险性。