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31.
32.
Mumby PJ Edwards AJ Arias-González JE Lindeman KC Blackwell PG Gall A Gorczynska MI Harborne AR Pescod CL Renken H Wabnitz CC Llewellyn G 《Nature》2004,427(6974):533-536
Mangrove forests are one of the world's most threatened tropical ecosystems with global loss exceeding 35% (ref. 1). Juvenile coral reef fish often inhabit mangroves, but the importance of these nurseries to reef fish population dynamics has not been quantified. Indeed, mangroves might be expected to have negligible influence on reef fish communities: juvenile fish can inhabit alternative habitats and fish populations may be regulated by other limiting factors such as larval supply or fishing. Here we show that mangroves are unexpectedly important, serving as an intermediate nursery habitat that may increase the survivorship of young fish. Mangroves in the Caribbean strongly influence the community structure of fish on neighbouring coral reefs. In addition, the biomass of several commercially important species is more than doubled when adult habitat is connected to mangroves. The largest herbivorous fish in the Atlantic, Scarus guacamaia, has a functional dependency on mangroves and has suffered local extinction after mangrove removal. Current rates of mangrove deforestation are likely to have severe deleterious consequences for the ecosystem function, fisheries productivity and resilience of reefs. Conservation efforts should protect connected corridors of mangroves, seagrass beds and coral reefs. 相似文献
33.
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive 总被引:1,自引:0,他引:1
Guccione E Bassi C Casadio F Martinato F Cesaroni M Schuchlautz H Lüscher B Amati B 《Nature》2007,449(7164):933-937
34.
Walter F Decarli R Carilli C Bertoldi F Cox P Da Cunha E Daddi E Dickinson M Downes D Elbaz D Ellis R Hodge J Neri R Riechers DA Weiss A Bell E Dannerbauer H Krips M Krumholz M Lentati L Maiolino R Menten K Rix HW Robertson B Spinrad H Stark DP Stern D 《Nature》2012,486(7402):233-236
The Hubble Deep Field provides one of the deepest multiwavelength views of the distant Universe and has led to the detection of thousands of galaxies seen throughout cosmic time. An early map of the Hubble Deep Field at a wavelength of 850?micrometres, which is sensitive to dust emission powered by star formation, revealed the brightest source in the field, dubbed HDF?850.1 (ref. 2). For more than a decade, and despite significant efforts, no counterpart was found at shorter wavelengths, and it was not possible to determine its redshift, size or mass. Here we report a redshift of z = 5.183 for HDF?850.1, from a millimetre-wave molecular line scan. This places HDF?850.1 in a galaxy overdensity at z?≈?5.2, corresponding to a cosmic age of only 1.1?billion years after the Big Bang. This redshift is significantly higher than earlier estimates and higher than those of most of the hundreds of submillimetre-bright galaxies identified so far. The source has a star-formation rate of 850 solar masses per year and is spatially resolved on scales of 5 kiloparsecs, with an implied dynamical mass of about 1.3?×?10(11) solar masses, a significant fraction of which is present in the form of molecular gas. Despite our accurate determination of redshift and position, a counterpart emitting starlight remains elusive. 相似文献
35.
Raúl Ernesto Campos 《Journal of Natural History》2016,50(15-16):923-941
This study aimed to determine the susceptibility of stumps and internodes of bamboos to colonization by different types of macroinvertebrates and the formation of communities of different complexity. Semi-controlled field studies were carried out in a subtropical area of Argentina to analyse community structure, species richness of the aquatic macroinvertebrate communities and co-occurrences of predators and prey to delineate the food webs. Water-filled bamboos were sampled every season during a year by removing, without replacing, all water and macroinvertebrates. This study shows that the variation in the morphology of the container provides different resources, leading to segregation of species per container type, and allowing each of them to establish aquatic communities with differences in diversity. The Diptera was best represented in the communities of bamboos, where Culicidae showed the highest species richness and Ceratopogonidae were the most abundant numerically. Eleven taxa were present in both phytotelmata, 12 were unique in internodes and 13 in stumps. The community in internodes was composed of 21 taxa where mosquitoes were represented by Sabethini and Toxorhynchitini. By contrast, stumps were colonized by 24 taxa and Ceratopogonidae were numerically dominant. Regarding food webs established in stumps and internodes, no differences in length were found, except for the species that played equivalent roles in each of the studied phytotelmata. 相似文献
36.
Ernesto Lleras 《Systemic Practice and Action Research》1996,9(4):333-338
The purpose of this writing is to explore ways of changing the relationship of workers with technology from one of oppression to one of liberation. By studying some of the most common aspects of those relationships, and Heidegger's reflections on the topic, a new way to relate to technology is proposed. This way is basically related with the way we conceive work and thought, and how these conceptions are oppressive by being constricted to exaction of productivity and not to the whole of human interests. 相似文献
37.
Caitlin Collin Frank Hauser Ernesto Gonzalez de Valdivia Shizhong Li Julia Reisenberger Eva M. M. Carlsen Zaid Khan Niels Ø. Hansen Florian Puhm Leif Søndergaard Justyna Niemiec Magdalena Heninger Guilin R. Ren Cornelis J. P. Grimmelikhuijzen 《Cellular and molecular life sciences : CMLS》2013,70(21):4197-4197
38.
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites 总被引:54,自引:0,他引:54
Kwong PD Doyle ML Casper DJ Cicala C Leavitt SA Majeed S Steenbeke TD Venturi M Chaiken I Fung M Katinger H Parren PW Robinson J Van Ryk D Wang L Burton DR Freire E Wyatt R Sodroski J Hendrickson WA Arthos J 《Nature》2002,420(6916):678-682
The ability of human immunodeficiency virus (HIV-1) to persist and cause AIDS is dependent on its avoidance of antibody-mediated neutralization. The virus elicits abundant, envelope-directed antibodies that have little neutralization capacity. This lack of neutralization is paradoxical, given the functional conservation and exposure of receptor-binding sites on the gp120 envelope glycoprotein, which are larger than the typical antibody footprint and should therefore be accessible for antibody binding. Because gp120-receptor interactions involve conformational reorganization, we measured the entropies of binding for 20 gp120-reactive antibodies. Here we show that recognition by receptor-binding-site antibodies induces conformational change. Correlation with neutralization potency and analysis of receptor-antibody thermodynamic cycles suggested a receptor-binding-site 'conformational masking' mechanism of neutralization escape. To understand how such an escape mechanism would be compatible with virus-receptor interactions, we tested a soluble dodecameric receptor molecule and found that it neutralized primary HIV-1 isolates with great potency, showing that simultaneous binding of viral envelope glycoproteins by multiple receptors creates sufficient avidity to compensate for such masking. Because this solution is available for cell-surface receptors but not for most antibodies, conformational masking enables HIV-1 to maintain receptor binding and simultaneously to resist neutralization. 相似文献
39.
Neuronal polarization occurs shortly after mitosis. In neurons differentiating in vitro, axon formation follows the segregation of growth-promoting activities to only one of the multiple neurites that form after mitosis. It is unresolved whether such spatial restriction makes use of an intrinsic program, like during C. elegans embryo polarization, or is extrinsic and cue-mediated, as in migratory cells. Here we show that in hippocampal neurons in vitro, the axon consistently arises from the neurite that develops first after mitosis. Centrosomes, the Golgi apparatus and endosomes cluster together close to the area where the first neurite will form, which is in turn opposite from the plane of the last mitotic division. We show that the polarized activities of these organelles are necessary and sufficient for neuronal polarization: (1) polarized microtubule polymerization and membrane transport precedes first neurite formation, (2) neurons with more than one centrosome sprout more than one axon and (3) suppression of centrosome-mediated functions precludes polarization. We conclude that asymmetric centrosome-mediated dynamics in the early post-mitotic stage instruct neuronal polarity, implying that pre-mitotic mechanisms with a role in division orientation may in turn participate in this event. 相似文献
40.
Yasuda S Oceguera-Yanez F Kato T Okamoto M Yonemura S Terada Y Ishizaki T Narumiya S 《Nature》2004,428(6984):767-771
During mitosis, the mitotic spindle, a bipolar structure composed of microtubules (MTs) and associated motor proteins, segregates sister chromatids to daughter cells. Initially some MTs emanating from one centrosome attach to the kinetochore at the centromere of one of the duplicated chromosomes. This attachment allows rapid poleward movement of the bound chromosome. Subsequent attachment of the sister kinetochore to MTs growing from the other centrosome results in the bi-orientation of the chromosome, in which interactions between kinetochores and the plus ends of MTs are formed and stabilized. These processes ensure alignment of chromosomes during metaphase and their correct segregation during anaphase. Although many proteins constituting the kinetochore have been identified and extensively studied, the signalling responsible for MT capture and stabilization is unclear. Small GTPases of the Rho family regulate cell morphogenesis by organizing the actin cytoskeleton and regulating MT alignment and stabilization. We now show that one member of this family, Cdc42, and its effector, mDia3, regulate MT attachment to kinetochores. 相似文献