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111.
MSI and MSII made on ribosome in idling step of protein synthesis 总被引:56,自引:0,他引:56
112.
Androgen effect on genetic and goldthioglucose-induced obesity 总被引:1,自引:0,他引:1
113.
114.
Growth of the bacterial cell 总被引:56,自引:0,他引:56
115.
RNA-DNA hybrids at the cytological level 总被引:37,自引:0,他引:37
116.
Genetics of the alkaline phosphatase polymorphism of the human placenta 总被引:27,自引:0,他引:27
117.
A deficiency of the homeotic complex of the beetle Tribolium 总被引:10,自引:0,他引:10
In Drosophila, the establishment of regional commitments along most of the anterior/posterior axis of the developing embryo depends on two clusters of homeotic genes: the Antennapedia complex (ANT-C) and the bithorax complex (BX-C). The red flour beetle has a single complex (HOM-C) representing the homologues of the ANT-C and BX-C in juxtaposition. Beetles trans-heterozygous for two particular HOM-C mutations spontaneously generate a large deficiency, presumably by an exchange within the common region of two overlapping inversions. Genetic and molecular results indicate that this deficiency spans at least the interval between the Deformed and abdominal-A homologues. In deficiency homozygous embryos, all gnathal, thoracic and abdominal segments develop antennal appendages, suggesting that a gene(s) has been deleted that acts to distinguish trunk from head. There is no evidence that beetles have a homologue of the segmentation gene fushi tarazu of similar genomic location and function. On the basis of the genetic tractability, convenient genome size and organization of Tribolium, and its relatively long phylogenetic divergence from Drosophila (>300 million years), we have integrated developmental genetic and molecular analyses of the HOM-C. We isolated about 70 mutations in the complex representing at least six complementation groups. The homeotic phenotypes of adults and lethal embryos lead us to believe that these beetle genes are homologous with the Drosophila genes indicated in Fig. 1 (see text). 相似文献
118.
119.
Summary The biochemical development of the fetal brain in relation to maternal vitamin A restriction was studied in rats. The vitamin A status of pregnant rats was varied by supplying low, medium and adequate amounts (6, 40, and 100 g retinol/day/kg body weight, respectively) of vitamin A during pregnancy and suckling. The maternal vitamin A restriction caused an altered brain development in terms of tissue weight, DNA, RNA and protein levels, and biosynthesis of DNA and protein from [3H]-thymidine and [3H]-leucine, respectively. A dose-dependent effect of maternal vitamin A restriction on the metabolism of DNA, RNA and protein was noticed in the developing fetal brain of rats. 相似文献
120.
Hypothalamic histamine modulates adaptive behavior of rats at high environmental temperature 总被引:1,自引:0,他引:1
K. Fujimoto T. Sakata K. Ookuma M. Kurokawa A. Yamatodani H. Wada 《Cellular and molecular life sciences : CMLS》1990,46(3):283-285
Summary Histamine content in the rat hypothalamus was lower at 4°C and higher at 31°C compared to that at 21°C. Pretreatment with -fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase, attenuated both the increased level of hypothalamic histamine and rat adaptive behavior at 31°C. Increase of histamine content in the hypothalamus appears to be an important factor contributing to rat adaptive behavior to high environmental temperature. 相似文献